Atrial fibrillation is one of the commonest cardiac arrhythmia in the elderly, the incidence increased with increasing ages. Atrial fibrillation can induce severe cardiac insufficiency and thromboembolism, stroke is also a very important complication with high morbidity and mortality. Thus it is very necessary to pay special attention to the study of atrial fibrillation in the field of geriatric cardiovascular diseases.

Leu 7 monoclonal antibody and immunohistochemical technic were used to study the distribution of NK cells in human lymph node, tonsil, spleen and thymus. The results indicated that the NK cells predominately distributed in B cell area, such as germinal center of secondary follicle, which occured in lymph node and tonsil. A few NK cells were found in the paracortex and medulla of lymph node. In the spleen, the NK cells mainly located in the germinal center of splenic nodules and in the periphery of white pulp. However, the NK cells were never shown in the perarterial lymphatic sheath, some NK cells also scattered in the pulp cord and sinuses of red pulp. In the thymus, the NK cells were restricted in the medulla, and the number of NK cells reduced in the aged thymus. In addition, the Leu 7 antibody was reacted with epithelial cells, which located in the cortical periphery or thymic lobule. The morphology of NK cells in different lymphoid organs was similar. The staining intensity of Leu 7 antibody was identical both in the frozen and paraffin sections.

9 fetal and 7 juvenile thymuses were used to identify the asteroid cells on the frozen sections by immunohistochemical method. The results indicated that the thymic medulla, except B cells, contains a type of larger cells with small cytoplasmic processes, which has in common with B cell antigens, such as 1gM, 1gA, Leu14, BA-1, HLA-DR and light chain-Kappa, but they do not express OKB-2. Moreover, the asteroid cells do not reactive with T cell antibody and follicular dendritic cell antibody, and lack of ANAE activity. The asteroid cells in the fetal thymus are constantly located in the corticomedullary region, while, in the juveniles, the asteroid cells are mainly distributed within medulla or in the vicinity of Hassall's corpuscles. As regards the function of asteroid cells is not clear. Based on their distribution, it is probably associated with T cell maturation. On the morphologic ground, the asteroid cells are similar to interdigitating cells in thymus, the relationship between them has been discussed.

ObjectiveTo evaluate the clinical effect of sulfasalazine capsulae enterosolubilis with Yunnanbaiyao for ulcerative colitis. MethodsSixty patients with ulcerative colitis were randomly divided into two groups,thirty cases in treatment group and thirty cases in control group. Patients in treatment group received sulfasalazine capsulae enterosolubilis with Ytmnanbaiyao orally,patients in control group were given sulfasalazine capsulae enterosolubilis orally only. ResultsThe total effective rate of treatment group was 90. 0％ ,clinical recovery rate was 73.3％ ;The total effective rate of control group was 66.7％ ,clinical recovery rate was 43.3％ ,the differences was statistically significant(P ＜0.05). ConclusionThe clinical effect of sulfasalazine capsulae enterosolubilis with Yunnanbaiyao for ulcerative colitis was good,and should be used furthedy.

The incidence of hypoglycemic events in patients with type 2 diabetes around the period of fasting in Ramadan was compared under the treatment with combined insulin glargine and glimepiride. The results showed that the number of hypoglycemic events in patients with type 2 diabetes before, during and after the period of fasting in Ramadan was not different (P=0.238).

Diagnosis, Differential ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged ; Phytotherapy ; Subarachnoid Hemorrhage ; diagnosis ; drug therapy ; Syndrome ; Vasodilator Agents ; therapeutic use

Chromoblastomycosis, a chronic fungal infection of the skin and subcutaneous tissue, is known to be difficult to treat. Recently itraconazole has proved effective for treatment of this infection, but requires a prolonged treatment course. We experienced a case of chromoblastomycosis caused by Fonsecaea pedrosoi in a 68-year-old Korean man showing a complete resolution with a short course of oral itraconazole, 200 mg daily, for six weeks.
Aged ; Chromoblastomycosis* ; Humans ; Itraconazole* ; Skin ; Subcutaneous Tissue

Aged ; Aged, 80 and over ; Humans ; Male ; Pneumoconiosis ; diagnostic imaging ; Radiography, Thoracic ; Tin ; toxicity

Objective To explore the relationship between the single nucleotide polymorphisms(SNPs) of IVS13-98G/T of human protection of telomeres 1(hPOT1) genes and H.pylori infection.Methods A total of 150 cases of gastric carcinoma and 156 cancer-free controls were genotyped by polymerase chain reaction(PCR) and PCR-restriction fragment length polymorphism(PCR-RFLP) method.H.pylori was identified with PCR and Warthin-Starry methods.Results The frequencies of GG,GT,and TT genotypes of hPOT1IVS13-98 G/T were 22.00%,41.67% and 36.67% in patients and 24.36%,51.92%,and 23.72% in controls,respectively.The OR for any GT and GG genotype was 0.432(95% CI: 0.242-0.772,P=0.005) and 0.540(95% CI: 0.274-1.064,P=0.075) when compared with TT genotype,respectively.There were no differences in genotype distribution and allele frequency of IVS13-98 G/T polymorphism(?2=3.0257,P= 0.0820).hPOT1IVS13-98 G/T polymorphism was not correlated with H.pylori infection in gastric cancer.Conclusion Our results indicated that IVS13-98 G/T SNP of hPOT1 gene might be associated with reduced risk for gastric carcinoma,but not with H.pylori infection.

0.05); When the IAP level reached 20 cm H2O, there was significant elevation (P