There are many kinds of diseases in hepatic surgery department including hepatitis,hepatic cirrhosis, liver cancer etl. Most of them are very ditficult to diagnose and treat, so it's necessary to change our traditional clinical practice teaching mode.Role-playing mode increases the interaction between students and teachers, which can achieve the desired effect with entertainment. So role-playing is a new model of clinical teaching as a meaningful innovation.

The hormone ghrelin is secreted mainly by stomach ,and is the only nature ligand that had been found by now for growth hormone releasing hormone receptor. Although the action for stimulating the secretion of growth hormone is very strong, it's only one part of ghrelin's action. It has many other actions in pathology and physiology, some of which are independent of it's stimulation to growth hormone releasing, such as regulating appetite, maintaining the energy equilibrium etc. We can find ghrelin's action in many human disease. This article is a review for the study in these parts.

Objective Serum FIB has been established as a predictor of cardiovascular events. The aim of this study was to investigate the relationship of FIB with acute coronary syndrome (ACS) and severity of the ACS. Methods A total of 692 patients with ACS who underwent a definite diagnosis were selected. Ninety-nine patients without coronary heart disease severed as control group. Detail information were recorded in age, gender, history of alcoholic, smoking, hypertension. All patients were detected in FIB and some other biochemical indicators levels. Use the correlation analysis to find the relationship of FIB with grace scoring. Results With the increase of Grace risk level and coronary artery lesions and myocardial ischemia,the levels of FIB were significantly increased (P < 0.05).The correlation analysis showed that Grace scores had a positive correlation with FIB in ACS patients. The logistic regression analysis showed the FIB was the most prominent predictors for ACS. The areas under the ROC curve of FIB were 0.87 which suggested that FIB had a higher predictive value of ACS. Conclusion The levels of serum FIB is closely related to criticality of ACS. For the ACS patients,higher levels of FIB indicated higher Grace scores. FIB level may have important clinical value in early risk stratification evaluation of prognosis and treatment options.

Taking a national continuing education program with hand in hand mode as an example, the advantages and disadvantages of hand in hand mode and traditional mode are com-pared. Hand in hand mode realizes a door-to-door teaching, and the curriculum is more targeted. Moreover, the time and physical power of trainees are saved, so the training effect is better. The na-tional continuing medical education program withhand in hand is worthy of promotion in the teach-ing practice.

Objective To investigate the toxic effect of nona-ferroso-ferric oxide(Nano-Fe_3O_4),nano-silicon dioxide(Nano- SiO_2)and single walled carbon nanotubes(SWCNTs)on the lung and mechanism in rats.Methods Fourty-nine Wistar rats were randomly divided into 7 groups,the control group,low and high dose groups of three nanomaterials.The rats were exposed by intratracheal instillation once two days for 5 weeks,and then killed by abdominal aorta bloodletting.The pathology of lung,lactate dehydrogenase(LDH),total antioxidant capacity(T-AOC),superoxide dismutase(SOD),malondialdehyde(MDA),interleukin-1(IL- l),interleukin-6(IL-6)and tumor necrosis factor-?(TNF-?)in bronchoalveolar lavage fluid(BALF)were determined.Results The fibrous tubercle and the matrix inflammation of lung tissue was found in the experimental groups.The activities of T-AOC and SOD decreased while IL-6 concentration increased significantly in the experimental groups(P

Objective:To investigate serum nitric oxide(NO) and nitric oxide synthase (NOS) in the process of recurrent aphthous ulcer(RAU).Methods:Serum NO and NOS were measured with specific kits in 243 patients with RAU and 50 healthy controls.Results:Serum NO (?mol/L) in the heathy controls,the patient at stages of attack,healing and intermission was 73.15?12.30,118.50?18.95,82.11?10.00 and 81.26?12.15;NOS(?mol/L) 35.23?6.57,44.77?5.95,37.10?5.05 and 36.12?7.40,respectively.Conclussion:NO and NOS may play role in the development of RAU.

Objective To understand the scientific research competitive power in clinical medicine and the role of F1000 in assessment of scientific research competitive power in the top 10 colleges and universities in China . Methods F1000-covered papers on clinical medicine published by the top 10 colleges and universities in China from 2005 to 2014 were retrieved.A database was established using Excel and analyzed by SPSS 20.0.Results The number of F1000-covered papers increased significantly although the scientific achievements needed to be fur-ther recognized in the world.Conclusion The scientific research competitive power in colleges and universities can be effectively assessed in different aspects.The F1000-covered data are very convincing due to its strict operational mechanisms .

0 01) in the two groups were significantly different Conclusion After CPR in non hemorrhagic CA, quick infusion of polyglucose and sodium chloride solution is beneficial to the recovery of erythrocyte rheological parameters before CPR

Objective To evaluate the protective effects of oral administration of D-methionine tablets on noise-induced hearing loss.Methods A total of 203 volunteers were recruited and randomly divided into two groups:experimental group (n=113)and control group (n=90).The subjects in the experimental group received oral administration of D-methionine tablets(1 500 mg/day)and those in the control group received placebo for 3 days before impulse noise exposure.The routine audiometric evaluation and ABR testing were performed and recor-ded 1 day and 7 days post- noise exposure.The statistical analysis was carried out with SPSS 11.0.ResuIts The changes of hearing in all participators were observed after noise exposure.The results were as follow:The hearing thresh-olds at three time points were 40.5±9.3,51.7±12.3,44.1±11.4 dB nHL in experimental group and 41.5±8.9,62.4± 13.7,47.6±12.5 dB nHL in control group,respectlvely;the ABR I-V IPLs at three time points were 3.72±0.21 ms, 3.99±0.36 ms,3.82±0.25 ms in experimental group,while 3.71±0.22 ms,4.45±0.37 ms,3.85±0.34 ms in control group,respectively.There were statistically significant differences between the two groups.ConcIusion The oral adminis-tration of D-methionine tablets pre noise exposure can protect against noise-induced hearing loss.

Five compounds were isolated from the rhizome and roots of Rhodiola crenulata S.H.Fu.They werc identified as rhodionin (Ⅰ), rhodiosin(Ⅱ), tyrosol(Ⅲ), salidroside(Ⅳ) and gallic acid (Ⅴ), respectively, by UV, MS, 1H and 13CNMR spectroscopic and chemical reactions.