Magnetic endoscopic imaging (MEI)is a non-radiographic imaging technique that has been developed in recent years. MEI is capable of displaying real-time three dimensional images of the colonoscope shaft within the abdominal cavity. MEI system has been shown to be beneficial in increasing the cecal intubation rate,helping remove colonoscope insertion tube loops,reducing the duration of looping,assisting training of colonoscopy when compared with traditional colonoscopy. This article reviewed the progress in research on MEI.

Arsenic is known as a toxic metalloid, which mainly exists in inorganic forms such as arsenite and arsenate in the natural environment. A number of microorganisms have evolved different resistant mechanisms for arsenic detoxification to cope with the widespread distribution of the poisonous arsenic. Four distinct microbial arsenic-resistant mechanisms have been described including As(III) oxidation, cytoplasmic As(V) reduction, respiratory As(V) reduction, and As(III) methylation. These mechanisms confer arsenic resistance in microorganisms that play important roles in the transformation and geological cycle of arsenic. This review mainly focuses on the researches on these molecular mechanisms and potential application for environmental arsenic bioremediation using microorganisms.

Video-assisted thoracic surgery (VATS) is high-skilled operation,which is tacit,scene-related,hard to transfer and individualized.The action formation of VATS is implemented by action orientation,imitation,integration,training and automation.The skill acquisition of VATS involves four overlapping steps:studying examples to do analogy,developing abstract rules,slowly moving to the use of production rules and retrieving specific examples.Research on teaching methods of VATS in the view of tacit knowledge helps to learn this skill better and more quickly.

AIM: To explore the treatment methods of severe migraine. METHODS: 51 cases of severe migraine patients were treated with the combination of radix salviae militiorrhizae, diclofenac and sodium aescinate, and another 62 cases of severe migraine patients were treated with diclofenac alone. RESULTS: The efficacy of the combination is better than that of diclofenac alone (P

A sensitive immunocytochemical technique has been used to study the effect of Cordyceps Sinesis on the IgM and IgG antibody-forming cells in mouse spleen. The results indicate that after the mice have been treated for 7 days with Cordyceps Sinesis, their splenic nodules were increasing, the germinal centers became prominent and the marginal zones were thickening. The immunocytochemical results disclosed that a huge amount of IgM and IgG lymphocytes appeared in the splenic nodules, especially in the marginal zones, which were thickening due to the proliferation of the IgM-lymphocytes. In the red pulp, a large amount of IgM- and IgG-plasma cells were peripherally located in the terminal arteries or sinuses, indicating that it may be convenient for the plasma cells to release the antibodies into blood circulation. The results suggest that the Cordyceps Sinesis could stimulate the IgM-and IgG-lymphocytts to proliferate and promote the forming of antibodies.

Objective To evaluate endoscopic ultrasonography (EUS) in preoperative staging of gastric carcinoma,and to study the molecular biologic basis of its ultrasonic manifestation.Methods Sev-enty-four patients with gastric carcinoma were referred to EUS and staged preoperatively.The staging esults of EUS were compared with the histopathological staging and the expression of PTEN.Results The verall accuracy rate of EUS for determination of T staging was 82.4%(61/74),for T1,T2,T3 and T4 were 100.0%,72.7％,85.O％ and 78.9％,respectively.For N staging,EUS had the overall accuracy rate of 74.3%(55/74),with sensitivity and specificity of 80.8％ and 59.1％,respectively.The preoperative EUS for T and N staging of gastric carcinoma was of inverse correlation with the expression of PTEN.Conclusions EUS is an accurate staging modality in determining carcinoma invasive depth and lymph node involved,with a few exceptions of overstaging and understaging.However,EUS criteria to differentiate benign from malignant nodes still need to be further defined by future studies.The preoperative EUS for T and N staging could well display the molecular pathologic basis of gastric carcinoma.

Objective To study the effect of continuous positive airway pressure(CPAP) therapy for 56 clinical cases neonatal a-cute respiration prostration. Methods Based on the traditional treatment,CPAP assistant therapy were taken on 56 cases. The pressure of CAPA were adjusted according to the variations of clinical condition and blood gas value. Results After 6 - hour assistance of CPAP performance, the symptom of all cases had been abated, pa (O2) was increased, the normal CPAP applaying time was 28 hoours. The remarkable difference had been found compared to those in no CPAP practice(P

Objective To study the preventive effect of small-dose fluconazol adiministered in low frequency on nosocomial fungal infectoin.Methods The condition of nosocomial fungal infection among 200 patients in pediatric intensive care unit (PICU)were observed,who were suffered with serious infection or basic diseases and underwent broad-spectrum or ultra-broad spectrum antibiotic and steroid hormones treatment.These patients were divided imto treatment and control group.And the patients in treatment group received fluconazol[5 mg/(kg?time)once every 2 days,total 3 times,after that,twice 1 week till improved] to prevent fungal infection .The control group were treated with fluconazol [6-10 mg/(kg?time),once everyday for 10-14 days] after fungal infection.Results The incidence rate of nosocomial fungal infectoin of control group was 58.3%(56 out of 96 cases,which were 44 cases of mouth,5 cases of respiratory tract ,5 cases of digestive tract and 2 cases of urethra ) and that of treatment group was 1.9%(2 out of 104 cases, which were 2 cases of mouth).In control group,37 cases were cured,17 cases improved and 2 cases were not effective.Mouth fungal infection in treatment group was gently and cured with 1 or 2 times of local treatment .The treatment group didn′t occured liver function damage or aggravation.Conclusion For PICU patients, adiministration of small-dose flucomazol in low frequency is an effective and relatively safety method to prevent against nosocomial fungal infectoin.

Objective To explore the relationship between the serum level of leptin,growth hormone(GH),insulin like growth factor-1(IGF-1),insulin like growth factor binding protein-3(IGFBP-3)and those modulatine effects on fetal growth.Methods One hundred and thirty-five cases of newborns were divided into 4 groups according to the relationship between born weight and gestational age.Group A:premature infants small for gestational age(SGA),n=30.Group B:premature infants appropriate for gestational age(AGA),n=36.Group C:mature infants small for gestational age,n=32.Group D:mature infants appropriate for gestational age,n=37.All infants were measured se-rum leptin,GH,IGF-1 and IGFBP-3 level with radiommunosassay(RIA).Results There were significant difference in the levels of leptin,GH,IGF-1,IGFBP-3 as group C0.05).There were positive correlation between levels of leptin,IGF-1 and IGFBP-3 in group A,B and C,while,there was positive correlation between only level of IGF-1 in group D.Conclusions Leptin,IGF-1 and IGFBP-3 may play an important role in the fetal growth regulation of premature infants and IUGR infants.IGF-1 also regulate intrauterine growth of group D.Another side,in group D,Leptin,GH,IGF-1 and IGFBP-3 don't regulate fetal growth.

Objective Establishing a kind of analysis method about HPLC character spectra of native medicinal materials, Lonicera fulvotomentosa, in Guizhou province for supplying experiment basis to guide processing and quality control of Lonicera fulvotomentosa. Methods Making the Lonicera fulvotomentosa sample liquors with 50% carbinol solvent and vibrating 30 minutes by ultrasonic. Adopting high performance liquid chromatography RP-HPLC method, Luna C18 (2) (5 ?m, 250 mm ? 4.6 mm) chromatographic column, the volume flow 1.0 mL/min, the column temperature 30 ℃, the detection wavelength 238 nm, the mobile phase 0.2% phosphoric acid acetonitrile (A)-0.2% phosphoric acid solution (B), the gradient elution 0～15 min, A∶B=10%∶90%, 15～60 min, A∶B=10%∶90%→40%∶60%. Results Determined 9 common peak in character spectra of the Lonicera fulvotomentosa by detecting 10 group Lonicera fulvotomentosa medicine materials with referring to chlorogenic acid, the precision and stability and reiteration test RSD value all less than 3.0%. The similitude degree between the samples and the character spectras was more than 0.99 by evaluating ten batch of the samples with the similarity assessing soft, proving that the quality of the ten batch of the Lonicera fulvotomentosa medicine materials was stable and homogeneous. Conclusion The character spectra of the Lonicera fulvotomentosa was established to supply experiment basis for effectively controlling process, quality and standard of Lonicera fulvotomentosa.