3.EFFECTS OF GINSENOSIDES AND PANTOCRINE ON THE FUNCTION OF REPRODUCTIVE ENDOCRINE SYSTEM IN MALE RATS
Chinese Pharmacological Bulletin 1986;0(04):-
In vitro experiment, results showed the that the LH secretion of adenohypophysis incubated with Ginsenosides ( G ) and Pantoc-rine ( P ) was significantly increased, similar to the exciting effect of LRH which stimulats LH secretion. By addition of G or P and Indomethacin (an inhibitor of PGs synthesis) at the same time, however, the LH secretion was significantly decreased. It appears that PGs may be involved in the regulation of the exciting effect of G and P on LH secretion. The experiment in vivo also demonstrated that in healthy young male rats injected with P by S.c.,thetestosterone content in plasma had significant increase, that the binding capacity of testicular tissue to 125I-HCG (receptor function) did not change clearly.
4.A New Method for the Extraction of Tea-Polyphenols
Chinese Traditional and Herbal Drugs 1994;0(03):-
A new method for the extraction of tea-polypbenols (TP ) from tea using AlCl3 as precipitating agents was proposed. Compared with tbe traditional extraction method using organic solvents, it is shown that the new method is simple and can be operated easily. The extraction rate of TP by the new method could reach 10.5% and the content of the effective ingredients of TP could reach over 99.5%
5.Study on inhibition effect of alkaloid monomers from Sophora alopecuroides on in vitro cultured lung cancer cells
Zhuolin LU ; Ge HONG ; Haiying JI
International Journal of Biomedical Engineering 2014;37(6):328-331,后插1
Objective To investigate in vitro anti-tumor activity and the related mechanism of four alkaloid monomers from Sophora alopecuroides,and to evaluate their toxicity on normal cells,thereby to screen the drugs with high efficiency and low toxicity anti-tumor effects.Methods Methyl thiazolyl tetrazolium (MTT) assay was employed to determine the effects of four alkaloid monomers on the proliferation activity of human lung cancer cells and hamster lung cells.Morphology of apoptotic lung cancer cell nucleus was observed by laser scanning confocal microscopy with Hochest33342 staining.Cell apoptosis and necrosis were measured by Annexin Ⅴ-FITC/PI double staining.Results The four alkaloid monomers showed different degree of proliferation inhibition on lung cancer cells with dose dependent manner.Oxysophoridine had the strongest inhibition effect on lung cancer cells and the minimun toxicity on normal lung cells.Hochest33342 staining and flow cytometry analysis demonstrated that oxysophoridine could induce the apoptosis and necrosis of A549 cells.Conclusions All four alkaloid monomers have certain anti-tumor effect on lung cancer cells.Oxysophoridine is the most active one with high efficiency and low toxicity characteristics,which is suitable for use as anti-tumor drug candidate for further development.
6.Effect of preoperative neoadjuvant chemotherapy on cervical carcinoma
Chinese Journal of Primary Medicine and Pharmacy 2010;17(23):3175-3177
Objective To study the value of neoadjuvant chemotherapy in the treatment of cervical carcinoma. MethodsA clinical prospective study was carried out from Jan.1997 to Dec.2003,118 patients with cervical carcinoma were given two cycles of combined chemotherapy before operation(neoadjuvant chemotherapy group,group A).102 patients accepted surgery alone in our hospital from Jan.1997 to Dec.2003 were chosen as the comparison group(group B).Survival rate and complications were observed and analysed. Results5 year survival rate in group A was significantly higher than that in group B(P<0.01),The 5 year survival rate was significantly higher in group A than in group B,despite of different pathological types,with or without radiochemotherapy(P<0.05).The recurrent rate was lower in group A than that in group B,which show significant difference in the 5 year recurrent rate(P<0.05). ConclusionNeoadjuvant chemotherapy is an effective method for the treatment of cervical carcinoma in early stage.Because of satisfactory short-term control rate,excision rate,long-term survival rate and low recurrent and metastatic rate,neoadjuvant chemotherapy is worth popularizing in clinical treatment.
7.Hip stress technical strength training and evaluation:Document comparison and logical analysis
Qi GE ; Tao HONG ; Bingcheng WANG
Chinese Journal of Tissue Engineering Research 2013;(46):8083-8089
BACKGROUND:At the beginning of the 20th century a strength training method in the backward direction appeared:hip stress strength training method. There are many articles focusing on the concept, function, effect and mechanism of this training method. So far, relevant research has formed a unique branch of special strength training research directions.
OBJECTIVE:To conclude the concept, function, effect, features and mechanisms of hip stress technical strength training through the systematic analysis of literature concerning hip stress strength training. METHODS:CNKI (1998/2010) and Wanfang databases were searched by the first author for relevant articles. The keywords were“hip stress, strength training, trajectory control, exercise training, muscle strength, knee, physical fitness, bone”in Chinese and English. The obtained data were summarized using contrast method and logic analysis method.
RESULTS AND CONCLUSION:Total y 90 papers were retrieved, and final y 34 papers were included. The results showed that the hip technical strength training method is the most effective training method currently to cultivate the running, jumping and throwing back pedaling force after hip extension forces. It has a new training idea and special training equipments, which can effectively solve many sports difficulties in strength training and technical training and has the vital significance for the high-level sports training, skil s assessment and sports teaching. Hip stress special technical strength training research has formed a special research branch of special strength trainings, which wil play a more significant research role.
8.Clinical Observation on Comprehensive Treatment of 80 Cases of Chronic Type Ⅲ Prostatitis by Elongated Needle, Microwave and Moritatherapy
Hui LI ; Hong ZHANG ; Jianqiang GE
Journal of Acupuncture and Tuina Science 2005;3(6):8-10
After 160 cases of chronic type Ⅲ prostatitis were divided into the treatment group (n= 80) and control group (n = 80), in the treatment group, first Zhibian (BL 54) was punctured toward Shuidao (ST 28) and then Qihai (CV 6), Guanyuan (CV 4), Shuidao (ST 28)Baihui (GV 20), Fengchi (GB 20), Sishencong (Ex-HN 1), Sanyinjiao (SP 6) and Taichong (LR 3) were punctured, and at the same time, digital computerized microwave apparatus was inserted into the anus for microwave treatment. Afterward, moritatherapy was applied for psychological consultation for the patients. In the control group, compound sinomin and Phenoxybenzamine Hydrochloride Tablets were used orally. The results showed that the therapeutic effects were respectively 92.5% and 68.8% in two groups, with statistic significance (P < 0.01).
10.Analysis and treatment of 13 histiocytic necrotizing lymphadenitis cases.
Hong-jun XU ; Ge GAO ; Li-feng AN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2011;46(7):590-591
Adolescent
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Adult
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Female
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Histiocytic Necrotizing Lymphadenitis
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diagnosis
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therapy
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Humans
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Lymph Nodes
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Male
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Middle Aged
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Neck
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Young Adult