1.Application value of cataract extraction surgery in the treatment of primary angle-closure glaucoma and cataract
Chinese Journal of Primary Medicine and Pharmacy 2016;23(8):1236-1239
Objective To investigate the application value of cataract extraction surgery in the treatment of primary angle-closure glaucoma and cataract.Methods 132 patients of primary angle-closure glaucoma and cata-ract were randomly selected,these patients were divided into lensectomy treatment group(A group,n=66) and laser peripheral iridotomy treatment group(B group,n=66) according to the treatment method.The visual acuity,intraocu-lar pressure,anterior chamber depth,and complications of the two groups were analyzed statistically.Results In A group,the visual acuity <0.1 was in 0 case,0.1-0.3 in 12 cases,>0.3-0.4 in 20 cases,>0.4 in 34 cases, accounting for 0.00%,18.18%,30.30%,51.52%.In B group,the visual acuity <0.1 was in 5 cases,0.1-0.3 in 14 cases,>0.3-0.4 in 19 cases,>0.4 in 28 cases,accounting for 7.58%,21.21%,28.79%,42.42%.A group of visual acuity <0.1 proportion of patients was significantly lower than B group(χ2 =5.02,P<0.05) ,the propor-tion of patients >0.4 was significantly higher than B group(χ2 =7.38,P<0.05),but the differences of the propor-tion for 0.1-0.3,>0.3-0.4 vision between the two groups were not significant(χ2 =2.71,4.61,all P>0.05). The differences of the intraocular pressure and anterior chamber depth before surgery between the two groups were not significant(t=1.532,1.447,all P>0.05),the anterior chamber depth after surgery in group A was significantly lon-ger than B group(t=2.571,P<0.05),but the difference of IOP between the two groups was not significant(t=1.032,P>0.05).A group had corneal edema in 1 case,a transient high IOP in 4 cases,2 cases in hyphema,the postoperative complication rate was 10.61%.B group had corneal edema in 1 case,a transient high IOP in 4 cases, 2 cases in hyphema,the postoperative complication rate was 10.61%,the incidence rate of postoperative complica-tions in A group was significantly lower than B group(χ2 =9.35,P<0.05).Conclusion The application value of cataract extraction surgery in the treatment of primary angle -closure glaucoma and cataract is higher than laser peripheral iridotomy,which can more effectively improve visual acuity, prolong anterior chamber depth, reduce inci-dence of complications of patients,so it is more safe and effective,and worthy of promotion.
2.Effect of gestational diabetes mellitus on perinatal outcome
Chinese Journal of Primary Medicine and Pharmacy 2014;21(1):21-23
Objective To investigate the women during pregnancy because of various reason caused by the impact of diabetes on perinatal outcome.Methods The delivery 24-28 weeks pregnant or first diagnosed more than 28 weeks after the gynecology clinic diagnosis with diabetes in 125 singleton pregnant women and newborns were selected as the research object of study.Except giving birth to the same period 95 cases of normal of diabetes single fetus of pregnant women and their newborn for the control group.The complications of pregnancy and gestational age,birth and neonatal intrauterine nutrition status,mode of delivery,neonatal asphyxia,hypoglycemia and jaundice,case analysis,comparison.Results The two groups in the average age,average number of pregnancy pregnancy and intrauterine nutrition(group GDM,PI =2.717,control group 2.469) and the rate of neonatal asphyxia were not statistically significant(P > 0.05).GDM group of 71 cases of cesarean section,natural childbirth in 54 cases,31 cases of control group difference and 64 cases,very significant differences between the two groups (x2 =12.678,P < 0.01),group GDM,the incidence of neonatal jaundice neonatal hypoglycemia respectively 18.4%,24%,and 7.4% in the control group,there was significant difference compared with 12.6% (x2 =4.500,5.577,all P <0.05).Conclusion Gestational diabetes is the important reason which caused by adverse perinatal outcome.
3.Value analysis of the application of hemorheology test in diagnosis and treatment of malignant tumor
International Journal of Laboratory Medicine 2015;(11):1589-1590
Objective To explore the value of the application of hemorheology test in diagnosis and treatment of malignant tumor .Methods A total of 100 patients suffered from malignant tumors selected as study group ,and divided as distant metastasis subgroup and no distant metastasis subgroup ,meanwhile 50 healthy persons were selected into control group .Test results of hemo‐rheology were compared .Results The whole blood viscosity ,erythrocyte aggregation index ,fibrinogen levels in the distant metasta‐sis subgroup were significant higher than those of the no distant metastasis group ,and the hematokrit level was significant lower than that of the no distant metastasis group ,the differences were statistical significant(P< 0 .05) .The parameters of hemorheology in the distant metastasis subgroup were significant different with that of the control group(P< 0 .05) .Except for erythrocyte aggre‐gation index ,other parameters of hemorheology were also significant different with those of the control group(P < 0 .05) .After treatment the whole blood viscosity ,packed cell volume and plasma viscosity had improved significantly comparing with before treatment(P< 0 .05) .Conclusion In the process of diagnosis and treatment of malignant tumors ,test indicators in hemorheology are constantly changing with the progress of the disease ,which has important application value .
4.Medical nutrition therapy for diabetes: a revisit
Chinese Journal of Endocrinology and Metabolism 2014;30(7):545-547
Nutritional therapy constitutes the basis for the integrated treatment of diabetes.It is essential for diabetic dietary management to be an individualized and balanced diet pattern based on total calorie control Carbohydrates is the main dietary ingredient to affect postprandial blood glucose levels.Dietary structure,way of eating,and physical exercise all contribute to the control of postprandial blood glucose levels.
5.Progress in immunopathogenesis of Henoch-Schonlein purpura
Chinese Pediatric Emergency Medicine 2015;22(3):190-193
Henoch-Schonlein purpura is a common general small-vessel vasculitis among children.The purpura repeated easily.It's called Henoch-Schonlein purpura nephritis when kidney is involved.The pathogenesis of Henoch-Schonlein purpura is unknown.In many researches,the levels of serum cytokines are abnormal expression,such as IL-6,IL-21,and IL-33.In rencent researches,cytokines' abnormal expression plays a fatal role in pathogenesis of Henoch-Schonlein purpura and Henoch-Schonlein purpura nephritis.
7.The etiology and prevention of neonatal iatrogenic pneumothora
International Journal of Pediatrics 2011;38(4):328-330
The side effects of cesarean with the increasing rate section began to attract the attention of pediatricians in recent years. Previous studies reported that the incidence of neonatal pnermothorax by full-term cesarean section, especially selective cesarean section, was significantly higher than vaginal birth or non-selective cesarean section. In addition, with an extensive establishment of NICUs in China and widely use of mechanical ventilation, the rate of successful neonatal rescue was improved obviously, but the incidence of pneumothorax was increasing. Studies suggested that the incidence of neonatal iatrogenic pneumothorax was highly relevant with selective cesarean section and mechanical ventilation. The indications for cesarean section and mechanical ventilation should be carefully considered.
8.Clinical application of covered stents in treating esophageal malignant stenosis
Chinese Journal of Tissue Engineering Research 2010;14(4):702-705
OBJECTIVE: To explore the materials and selection of esophageal stents, and to discuss the application of covered stants in treating esophageal malignant stenosis.METHODS: CNKI and Medline databases were retrieved by computer for papers published from 1980 to 2009 with search terms of "esophageal carcinoma, esophageal stenosis, esophageal stent, and fabric-covered metallic stent". The language was limited for Chinese and English. A total of 61 iteratures were initial searched by computer, according to inclusive and exclusive criteria, 29 literatures were selected by the first author. Problems including esophageal stent category, material selection, as well as application of covered stents in treating esophageal malignant stenosis were reviewed and summarized.RESULTS: Totally 29 literatures were included in this paper. No concealed allocation or blinding method was described in the literatures. According to preparing materials, the stents could be divided into stainless metal stent, memory metallic stent and polyester plastic stent. As tissue-engineered materials, stents could be assigned into biodegradable polymer matrix stent and non-degradable biodegradable polymers stent. Each material stent possesses distinct advantage and disadvantage. The covered stents could relief esophageal stenosis effectively, interrupt tumor growth, and prevent restenosis. CONCLUSION: As a palliative therapy for treating esophageal malignant stenosis, covered stents can elevate patients' life quality and prolong survival times.
10.Application of Enterprise Master Patient Index in Hospital Clinical Information Integration
Journal of Medical Informatics 2015;(8):60-63
Taking Children's Hospital of Fudan University as an example, the paper establishes a patient identity matching model based on the historical treatment data according to features of pediatric patients.It also sets up a uniform indexing mechanism of the his-torical treatment and hospitalization records of the patients by improving the existing business system, providing support patient identity recognition and laying a foundation for establishment of the clinical data center in future.