1.24th Seah Cheng Siang Lecture: Seeing better, doing better--evolution and application of gastrointestinal (GI) endoscopy.
Annals of the Academy of Medicine, Singapore 2015;44(1):34-39
Gastrointestinal (GI) endoscopy has evolved tremendously from the early days when candlelight was used to illuminate scopes to the extent that it has now become an integral part of the practice of modern gastroenterology. The first gastroscope was a rigid scope first introduced by Adolf Kussmaul in 1868. However this scope suffered from the 2 drawbacks of poor illumination and high risk of instrumental perforation. Rudolf Schindler improved on this by inventing the semiflexible gastroscope in 1932. But it was Basil Hirschowitz, using the principle of light conduction in fibreoptics, who allowed us to "see well" for the first time when he invented the flexible gastroscopy in 1958. With amazing speed and innovation, instrument companies, chiefly Japanese, had improved on the Hirschowitz gastroscope and invented a flexible colonoscope. Walter McCune introduced the technique of endoscopic retrograde cholangiopancreatography (ERCP) in 1968 which has now evolved into a sophisticated procedure. The advent of the digital age in the 1980s saw the invention of the videoendoscope. Videoendoscopes have allowed us to start seeing the gastrointestinal tract (GIT) "better" with high magnification and resolution and optical/digital enhancements. Fusing confocal and light microscopy with endoscopy has allowed us to perform an "optical biopsy" of the GI mucosa. Development of endoscopic ultrasonography has allowed us to see "beyond" the GIT lumen. Seeing better has allowed us to do better. Endoscopists have ventured into newer procedures such as the resection of mucosal and submucosal tumours and the field of therapeutic GI endoscopy sees no end in sight.
Endoscopes, Gastrointestinal
;
Endoscopy, Gastrointestinal
;
Equipment Design
;
Gastrointestinal Diseases
;
diagnosis
;
surgery
;
Humans
;
Video Recording
2.A Case of an Intraluminal Duodenal Diverticulum Managed with Endoscopic Incision and Ligation using Needle-knife and Detachable Snare.
Young Dae PARK ; Yun Jin CHUNG ; Seong Woo JEON ; Chang Min CHO ; Won Young TAK ; Young Oh KWEON ; Sung Kook KIM ; Yong Hwan CHOI
The Korean Journal of Gastroenterology 2007;49(3):177-182
An intraluminal duodenal diverticulum (IDD) is a rare congenital anomaly consisted of a sac-like mucosal projection within the second portion of the duodenum. Even though most of cases are asymptomatic, patients may develop recurrent abdominal pain, pancreatitis, and gastrointestinal bleeding. We report a case of symptomatic IDD which presented as acute pancreatitis and obscure gastrointestinal bleeding. Diagnosis was made by typical findings of upper GI series and coronal reformatted CT images. Although surgical resection is the treatment of choice, endoscopic incision and ligation with detachable snare was performed which led to a good result.
Acute Disease
;
Adult
;
Diverticulum/radiography/*surgery
;
Duodenal Diseases/radiography/*surgery
;
*Endoscopes, Gastrointestinal
;
Endoscopy, Gastrointestinal
;
Female
;
Gastrointestinal Hemorrhage/diagnosis
;
Humans
;
Pancreatitis/diagnosis
3.Clinical characters of gastrointestinal lesions in intestinal Behcet's disease.
Wei-bin WANG ; Yu-pei ZHAO ; Lin CONG ; Hao JING ; Quan LIAO ; Tai-ping ZHANG
Chinese Medical Sciences Journal 2011;26(3):168-171
OBJECTIVETo investigate the clinical features, diagnosis methods, therapeutic principles of intestinal Behcet's disease.
METHODSking Union Medical College Hospital from August 1998 to April 2010 were retrospectively analyzed.
RESULTSThe clinical courses of patients with intestinal Behcet's disease were from 26 days to 33 years, and the average duration was 6.32 +/- 1.01 years. The appearance of extra-gastrointestinal symptoms was significantly earlier than that of gastrointestinal symptoms (7.35 +/- 1.39 years vs. 3.24 +/- 0.82 years, P<0.05). The predominant gastrointestinal manifestations were right lower quadrant pain (95.56%) and hematochezia or melena (40.00%). Misdiagnosis occurred in 17 cases. In patients without systemic medicine therapy before surgery, the incidence of postoperative infection of incision site and abdominal cavity was significantly higher than that in those undergoing systemic medicine therapy (80.00% vs. 0%, P<0.05).
CONCLUSIONSBecause of the diversity of gastrointestinal manifestations, intestinal Behcet's disease is easily misdiagnosed. The systemic medical therapy before surgery could decrease the incidence of infection of incision and abdominal cavity.
Adolescent ; Adult ; Aged ; Behcet Syndrome ; diagnosis ; pathology ; surgery ; Child ; Female ; Gastrointestinal Diseases ; diagnosis ; pathology ; surgery ; Humans ; Intestinal Diseases ; diagnosis ; pathology ; surgery ; Male ; Middle Aged ; Young Adult
4.Acute Lower Gastrointestinal Bleeding from the Appendix Diagnosed by Colonoscopy.
The Korean Journal of Gastroenterology 2010;56(6):339-340
No abstract available.
Acute Disease
;
Appendectomy
;
*Appendix
;
Cecal Diseases/*diagnosis/surgery
;
Colonoscopy
;
Gastrointestinal Hemorrhage/*diagnosis/surgery
;
Humans
;
Male
;
Middle Aged
5.What Are the Risk Factors for Delayed Post-polypectomy Bleeding?.
The Korean Journal of Gastroenterology 2012;59(6):393-394
No abstract available.
Colonic Diseases/*diagnosis
;
Colonic Polyps/*surgery
;
Female
;
Gastrointestinal Hemorrhage/*etiology
;
Humans
;
Male
6.Clinical Outcomes Associated with Treatment Modalities for Gastrointestinal Bezoars.
So Eun PARK ; Ji Yong AHN ; Hwoon Yong JUNG ; Shin NA ; Se Jeong PARK ; Hyun LIM ; Kwi Sook CHOI ; Jeong Hoon LEE ; Do Hoon KIM ; Kee Don CHOI ; Ho June SONG ; Gin Hyug LEE ; Jin Ho KIM
Gut and Liver 2014;8(4):400-407
BACKGROUND/AIMS: With technical and instrumental advances, the endoscopic removal of bezoars is now more common than conventional surgical removal. We investigated the clinical outcomes in a patient cohort with gastrointestinal bezoars removed using different treatment modalities. METHODS: Between June 1989 and March 2012, 93 patients with gastrointestinal bezoars underwent endoscopic or surgical procedures at the Asan Medical Center. These patients were divided into endoscopic (n=39) and surgical (n=54) treatment groups in accordance with the initial treatment modality. The clinical feature and outcomes of these two groups were analyzed retrospectively. RESULTS: The median follow-up period was 13 months (interquartile range [IQR], 0 to 77 months) in 93 patients with a median age of 60 years (IQR, 50 to 73 years). Among the initial symptoms, abdominal pain was the most common chief complaint (72.1%). The bezoars were commonly located in the stomach (82.1%) in the endoscopic treatment group and in the small bowel (66.7%) in the surgical treatment group. The success rates of endoscopic and surgical treatment were 89.7% and 98.1%, and the complication rates were 12.8% and 33.3%, respectively. CONCLUSIONS: Endoscopic removal of a gastrointestinal bezoar is an effective treatment modality; however, surgical removal is needed in some cases.
Abdominal Pain/etiology
;
Aged
;
Bezoars/diagnosis/*surgery
;
Endoscopy, Gastrointestinal/methods
;
Female
;
Gastrointestinal Diseases/diagnosis/*surgery
;
Humans
;
Lithotripsy/methods
;
Male
;
Middle Aged
;
Retrospective Studies
;
Treatment Outcome
7.Management of Intramural Esophageal Dissection with Gastric Feeding Tube in an Alcoholic-hepatitis Patient.
Ryoung Eun KO ; Won Sik JUNG ; Yoon Chae LEE ; Sung Hoon CHOI ; Seung Young SEO
The Korean Journal of Gastroenterology 2016;67(1):35-38
Intramural esophageal dissection is a rare but clinically important condition in the field of gastroenterology. Classically, intramural esophageal dissection rarely occurs in patients who are anticoagulated or have poor medical condition, and its clinical presentation may include chest pain, dysphagia and hematemesis. Herein, we present a case of intramural esophageal dissection in an alcoholic hepatitis patient that was diagnosed by endoscopy and successfully treated with conservative management.
Deglutition Disorders/diagnosis
;
Enteral Nutrition
;
Esophageal Diseases/*diagnosis/surgery
;
Esophagoscopy
;
Hepatitis, Alcoholic/*pathology
;
Humans
;
Intubation, Gastrointestinal
;
Male
;
Middle Aged
8.Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases.
Li TANG ; Liu-Ye HUANG ; Jun CUI ; Cheng-Rong WU
Chinese Medical Journal 2018;131(11):1321-1326
BackgroundThe diagnosis and treatment of small-bowel diseases is clinically difficult. The purpose of this study was to evaluate the diagnostic and therapeutic value of double-balloon enteroscopy in small-bowel diseases.
MethodsThe history and outcomes of 2806 patients who underwent double-balloon enteroscopy from July 2004 to April 2017 were reviewed, which included 562 patients with obscure digestive tract bleeding, 457 patients with obscure diarrhea, 930 patients with obscure abdominal pain, 795 patients with obscure weight loss, and 62 patients with obscure intestinal obstruction. Examinations were performed through the mouth and/or anus according to the clinical symptoms and abdominal images. If a lesion was not detected through one direction, examination through the other direction was performed as necessary. Eighty-four patients with small-bowel polyps, 26 with intestinal obstruction caused by enterolith, and 18 with bleeding from Dieulafoy's lesions in the small intestine were treated endoscopically.
ResultsA total of 2806 patients underwent double-balloon enteroscopy, and no serious complications occurred. An endoscopic approach through both the mouth and anus was used in 212 patients. Lesions were detected in 1696 patients, with a detection rate of 60.4%; the rates for obscure digestive tract bleeding, diarrhea, abdominal pain, weight loss, and intestinal obstruction were 85.9% (483/562), 73.5% (336/457), 48.2% (448/930), 49.1% (390/795), and 62.9% (39/62), respectively. For patients with small-bowel polyps who underwent endoscopic therapy, no complications such as digestive tract bleeding and perforation occurred. Intestinal obstruction with enteroliths was relieved with endoscopic lithotripsy. Among the 18 patients with bleeding from small-bowel Dieulafoy's lesions, 14 patients were controlled with endoscopic hemostasis.
ConclusionDouble-balloon enteroscopy is useful for diagnosing and treating some small-bowel disease.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Double-Balloon Enteroscopy ; methods ; Female ; Gastrointestinal Hemorrhage ; diagnosis ; surgery ; Humans ; Intestinal Diseases ; diagnosis ; surgery ; Intestinal Obstruction ; Intestine, Small ; diagnostic imaging ; Leiomyosarcoma ; diagnosis ; surgery ; Lymphoma ; diagnosis ; surgery ; Male ; Middle Aged ; Polyps ; diagnosis ; surgery ; Young Adult
9.A Case of Recurrent Intestinal Obstruction Caused by Meckel's Diverticulum.
Eun Yeong KIM ; Jae Myung CHA ; Joung Il LEE ; Jae Won CHOE ; Kwang Ro JOO ; Sung Won JUNG ; Hyun Phil SHIN ; Suk Hwan LEE
The Korean Journal of Gastroenterology 2008;51(6):372-376
Meckel's diverticulum is the most common anomaly of the intestine. It is usually asymptomatic but approximately 4% are symptomatic with complications such as bleeding, intestinal obstruction, and inflammation. Gastrointestinal bleeding is the most common presenting symptoms of Meckel's diverticulum in children, however, intestinal obstruction is the most common complications in adult patients. Reported mechanism of intestinal obstruction in Meckel's diverticulum include intussusception, adhesion, and volvulus. Recently, we experienced a case with Meckel's diverticulum associated with ileal stricture causing recurrent partial intestinal obstruction in a 48-year-old man. In contrast to other published cases of small bowel obstruction in Meckel's diverticulum, this case was caused by ileal stricture associated with Meckel's diverticulum.
Endoscopy, Gastrointestinal
;
Humans
;
Ileal Diseases/*diagnosis/*etiology/surgery
;
Intestinal Obstruction/*diagnosis/etiology/surgery
;
Male
;
Meckel Diverticulum/*complications/pathology/surgery
;
Middle Aged
;
Recurrence
10.Sigmoid Colon Diverticular Bleeding in a 75-year-old Woman.
Jeoung Ho CHOI ; Young Sook PARK ; Chae Young LIM ; Jun Young JUNG ; Seong Hwan KIM ; Won Mi LEE ; Jun Kil HAN ; Yun Young JUNG
The Korean Journal of Gastroenterology 2009;53(2):111-115
Most common cause of brisk hematochezia is diverticular bleeding in Western countries. It occurs in 15% of patients with diverticulosis and one-third of them appear to be massive. Most of diverticulosis in Western countries occur in the left colon but the right colon is more common in Korea. Especially, the reports of diverticular bleeding on left colon are rare in Korea. We report a case presenting with multiple diverticuli complicated by recurrent massive bleeding restricted to the left colon. 75-year-old female was admitted due to hematochezia and dizziness. On past history, two years and two weeks ago respectively, she was treated of diverticular bleeding with and without diverticulitis. Hemoglobin level was 9.8 g/dL. On Colonoscopy, numerous diverticuli were seen at sigmoid colon upto splenic flexure which showed fresh blood clots in the lumen. We diagnosed her as recurrent massive diverticular bleeding on the sigmoid colon. She received elective laparoscopic left hemicolectomy.
Aged
;
Colonoscopy
;
Diagnosis, Differential
;
Diverticulosis, Colonic/complications/*diagnosis/surgery
;
Female
;
Gastrointestinal Hemorrhage/*diagnosis/etiology/therapy
;
Humans
;
Recurrence
;
Sigmoid Diseases/*diagnosis/etiology/therapy
;
Tomography, X-Ray Computed