Gastrointestinal motility modulating drugs include all compounds which have pharmacological activity of modulating (stimulating or inhibiting) gastrointestinal motility. They are mainly used for the treatment of functional gastrointestinal diseases. Gastrointestinal motility modulating drugs include 5HT receptor agonists, antagonists, and antidopaminergic agents. Many new gastrointestinal motility modulating drugs are currently under investigation. The aims of this article are to review the mechanism of action, efficacy and side effects of the gastrointestinal motility modulating drugs.
Gastrointestinal Diseases ; Gastrointestinal Motility

No abstract available.
Gastrointestinal Diseases*

No abstract available.
Gastrointestinal Diseases*

No abstract available.
Gastrointestinal Diseases*

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Gastrointestinal Diseases*

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Gastrointestinal Diseases*

No abstract available.
Gastrointestinal Diseases ; Neuropeptides ; Phenotype

Laparoscopic surgery describes the performance of surgical procedure with the assistance of a video camera and several other instruments. It is now being used in all surgical fields and especially operations for gastrointestinal diseases adopting a laparoscopic procedure in a relatively short period of time. Many benefits of minimally invasive surgery had been proved. With improvement in equipments, instrumentations, and surgical skills, it would be growing and be able to be approached for a more complex procedure. This paper briefly reviews the history, current status, and future of laparoscopic surgery.
Gastrointestinal Diseases ; Laparoscopy

We used mainly the Rome diagnostic criteria to diagnose functional gastrointestinal disease (FGID). The revised Rome IV was announced in 2016. Rome IV is the recognition that a considerable overlap exists between some of the FGIDs and that they may exist as part of a spectrum, rather than discrete disorders. Based on this concept, the Rome IV criteria for functional constipation and anorectal disorders are newly revised. We review the background and content of the Rome IV diagnostic criteria and introduce the multidimensional clinical profile using clinical cases. These revised criteria will be helpful for adequately diagnosing and managing these patients in actual clinical practice.
Constipation* ; Gastrointestinal Diseases ; Humans

Functional gastrointestinal disorders (FGIDs) are common and may be serious. As such disorders are identified principally on the basis of their symptoms, symptom-based classifications assume great importance. The Rome diagnostic criteria for FGIDs are widely used in both research and practice. Over time, the criteria have been revised as new data accumulate; the Rome IV criteria were recently released. The changes from the Rome III criteria principally reflect the data of literature reports and committee recommendations based on all available evidence. Here, we offer a historical perspective and discuss the Rome IV changes.
Classification ; Gastrointestinal Diseases