Gastritis cystica polyposa (GCP) is a rare lesion characterized by hyperplastic and cystic dilatation of the gastric mucous glands infiltrating into the underlying submucosa. A cumulative experience suggests that GCP represents a manifestation of a spectrum of reactive inflammatory responses to mucosal injury. The case reported herein is a GCP developed as multiple polypoid lesions with a circular arrangement in the gastric mucosae along the gastrojejunostomy site.
Dilatation ; Gastric Bypass ; Gastric Mucosa ; Gastritis*

No abstract available.
Bulimia* ; Gastric Dilatation* ; Ischemia* ; Portal Vein*

Gastritis cystica profunda (GCP) is a disease characterized by gastric foveolae elongation along with hyperplasia and cystic dilatation of the gastric glands extending into the tisssue beneath the submucosa. It mainly occurs on the site of gastroenterostomy, but can occasionally be found in an unoperated stomach. GCP may present as a submucosal tumor or polyp, and rarely a giant gastric mucosal fold. This lesion has traditonally been regarded as a benign lesion. However, there are many debates over its malignant potential. Further investigations on the relation between GCP and gastric carcinoma may be necessary. To our knowledge, this is the second description of adenocarcinoma arising from GCP in an unoperated stomach.
Adenocarcinoma* ; Dilatation ; Gastric Mucosa ; Gastritis* ; Gastroenterostomy ; Hyperplasia ; Polyps ; Stomach

Enteroenteric anastomotic strictures of UGI tract are common and require treatment if significant obstruction occurs. We performed fluoroscopic guided balloon dilatation in 6 patients who had symptomatic stricture of gastrojejunostomy. The stricture was successfully resolved in 4 patients with benign stricture. But 2 patients with malignant stricture had recurrence of obstructive symptom 2 weeks later, and they required a stent. Asymptomatic balloon rupture was seen in one patient, but other procedural complications did not occur. We found that fluoroscopic guided balloon dilatation is an effective and safe method in the treatment of anastomotic stricture of gastrojejunostomy. We also found transient effect in malignant gastrojejunal anastomotic strictures, which required an interventional procedure, such as placement of a stent.
Constriction, Pathologic* ; Dilatation* ; Gastric Bypass* ; Humans ; Methods ; Recurrence ; Rupture ; Stents

Enteroenteric anastomotic strictures of UGI tract are common and require treatment if significant obstruction occurs. We performed fluoroscopic guided balloon dilatation in 6 patients who had symptomatic stricture of gastrojejunostomy. The stricture was successfully resolved in 4 patients with benign stricture. But 2 patients with malignant stricture had recurrence of obstructive symptom 2 weeks later, and they required a stent. Asymptomatic balloon rupture was seen in one patient, but other procedural complications did not occur. We found that fluoroscopic guided balloon dilatation is an effective and safe method in the treatment of anastomotic stricture of gastrojejunostomy. We also found transient effect in malignant gastrojejunal anastomotic strictures, which required an interventional procedure, such as placement of a stent.
Constriction, Pathologic* ; Dilatation* ; Gastric Bypass* ; Humans ; Methods ; Recurrence ; Rupture ; Stents

We introduce a rare case of gastric emphysema. A 68-year-old man presented with vomiting and dyspnea. Simple abdominal X-ray and CT showed marked dilatation of the stomach and abnormal intramural gas consistent with gastric emphysema. We performed gastric decompression via nasogastric tube drainage and parenteral nutritional support. Nine days after admission, the abnormal intramural gas had disappeared on follow-up CT. The acute gastric dilatation in this patient may have resulted from gastric hypomotility as a result of diabetic gastroparesis in addition to superior mesenteric artery syndrome resulting from malnutrition.
Aged ; Decompression ; Dilatation ; Drainage ; Dyspnea ; Emphysema ; Follow-Up Studies ; Gastric Dilatation ; Gastric Outlet Obstruction ; Gastroparesis ; Humans ; Malnutrition ; Mesenteric Artery, Superior ; Nutritional Support ; Stomach ; Superior Mesenteric Artery Syndrome ; Vomiting

PURPOSE: Paclitaxel is a chemotherapeutic agent with potent microtubule stabilizing activity that arrests cells in G2-M phase. Because G2 and M are the most radiosensitive phase of the cell cycle, paclitaxel has potential role as a cell-cycle specific radiosensitizer. This study was performed to see the effects of paclitaxel on the radiation-induced damage of gastric mucosa of the rat. MATERIALS AND METHODS: The rats were divided into the three groups i.e., paclitaxel alone group, radiation alone group and, a combination of paclitaxel and radiation in combined group. A single intraperitoneal infusion of paclitaxel (10 mg/kg) was done in paclitaxel alone group. In radiation alone group, a single fraction of irradiation (8 Gy, x-ray) to the whole abdomen and, a combination of a single fraction of irradiation (8 Gy, x-ray) to the whole abdomen was given 24 hrs after paclitaxel infusion in combined group of paclitaxel and radiation. The incidence of mitosis and apoptosis as well as histologic changes of the gastric mucosa were evaluated at 6 hrs, 24 hrs, 3 days and 5 days after treatment. RESULTS: The number of the mitosis was not increased by paclitaxel infusion. The incidence of the apoptosis was similar from 6 hrs to 3 days after paclitaxel infusion and was decreased at 5 days. Paclitaxel induced minimal glandular dilatation and cellular atypia of gastric mucosa at 24 hrs and 3 days. In irradiation group, the incidence of apoptosis was 6.0% in 6 hrs and 1.25% in 24 hrs after irradiation and minimal glandular dilatation and cellular atypia were noted throughout the experimental period. The incidence of apoptosis in the combined group of paclitaxel and irradiation (4.5%) was significantly higher than irradiation alone group (1.25%) at 3 days (p<0.05). CONCLUSION: Paclitaxel had no effect on mitotic arrest in gastric mucosa of the rat. Increased number of apoptosis in combined paclitaxel and irradiation group suggested the additive effects of paclitaxel on irradiation.
Abdomen ; Animals ; Apoptosis ; Cell Cycle ; Dilatation ; Gastric Mucosa* ; Incidence ; Infusions, Parenteral ; Microtubules ; Mitosis ; Paclitaxel* ; Rats* ; Stomach

With Duchenne's muscular dystrophy, there are many descriptions from the view of skeletal muscle disorders. However, the functional impairment of smooth muscle can cause fatal problems. A case of a 13-year-old boy, with Duchenne's muscular dystrophy, who present with severe abdominal pain from acute gastric dilatation and acute calculous cholecystitis, is reported. The case is discussed, with a review of the literature.
Abdominal Pain ; Adolescent ; Cholecystitis* ; Gastric Dilatation* ; Humans ; Male ; Muscle, Skeletal ; Muscle, Smooth ; Muscular Dystrophies*

BACKGROUND/AIMS: The causes of gastric outlet obstruction (GOO) have changed from peptic ulcer disease (PUD) to malignant diseases in recent years. The aims of this study are to determine the relative incidence of malignany and other causative diseases, and to consider therapeutic and diagnostic usefulness of endoscopy. METHODS: 95 patients with GOO who diagnosed by radiologic and endoscopic examination or surgery were reviewed by causative diseases, clinical features, endoscopic findings and outcome of treatment. RESULTS: 1) The mean age was 57.5 years (M:F=2.4:1). 2) The causative diseases were gastric or duodenal malignancy (56.8%), complication of PUD (39.2%), and biliary and pancreatic disease (4.2%). 3) Malignancy was diagnosed by upper gastrointestinal (UGI) endoscopy in 95.8%; obstruction by complication of PUD was detected by endoscopy in 100%. 4) The most common endoscopic type of malignancy was Borrman type 3 (84.8%) and the most common benign lesions were duodenal or pyloric ulcer (94.5%). 5) The managements of malignancy were operation (53.5%), endoscopic stenting (18.5%), and conservative treatment (38.8%). The complications of PUD were treated by anti-ulcer medication (85.3%), endoscopic dilatation (4.8%) and operation (13.6%). CONCLUSIONS: The main causes of GOO are changed to malignancy in recent 5 years. Endoscopy is useful to detect the various causes of GOO, and necessary procedure to decide the method of their management.
Dilatation ; Endoscopy* ; Gastric Outlet Obstruction* ; Humans ; Incidence ; Pancreatic Diseases ; Peptic Ulcer ; Stents ; Ulcer

BACKGROUND/AIMS: The causes of gastric outlet obstruction (GOO) have changed from peptic ulcer disease (PUD) to malignant diseases in recent years. The aims of this study are to determine the relative incidence of malignany and other causative diseases, and to consider therapeutic and diagnostic usefulness of endoscopy. METHODS: 95 patients with GOO who diagnosed by radiologic and endoscopic examination or surgery were reviewed by causative diseases, clinical features, endoscopic findings and outcome of treatment. RESULTS: 1) The mean age was 57.5 years (M:F=2.4:1). 2) The causative diseases were gastric or duodenal malignancy (56.8%), complication of PUD (39.2%), and biliary and pancreatic disease (4.2%). 3) Malignancy was diagnosed by upper gastrointestinal (UGI) endoscopy in 95.8%; obstruction by complication of PUD was detected by endoscopy in 100%. 4) The most common endoscopic type of malignancy was Borrman type 3 (84.8%) and the most common benign lesions were duodenal or pyloric ulcer (94.5%). 5) The managements of malignancy were operation (53.5%), endoscopic stenting (18.5%), and conservative treatment (38.8%). The complications of PUD were treated by anti-ulcer medication (85.3%), endoscopic dilatation (4.8%) and operation (13.6%). CONCLUSIONS: The main causes of GOO are changed to malignancy in recent 5 years. Endoscopy is useful to detect the various causes of GOO, and necessary procedure to decide the method of their management.
Dilatation ; Endoscopy* ; Gastric Outlet Obstruction* ; Humans ; Incidence ; Pancreatic Diseases ; Peptic Ulcer ; Stents ; Ulcer