No abstract available.
Blood Flow Velocity* ; Fetus* ; Gases*

BACKGROUND:This study was designed to compare hydroxyethylstarch (HES) to albumin in high-risk surgery patients infused over 72 h peri-operatively; hemodynamic changes, oxygen transport parameters, blood gases, blood coagulation, blood loss, blood use, outcome, and costs were compared. METHODS:High-risk surgical patients undergoing high-risk abdominal, cranial, and orthopaedic surgery were treated with 6% HES (130/0.4; n = 41) or 20% albumin (n = 19).The goal of volume therapy was to maintain a normal cardiac index (CI; 3.0 L/min/m2) over 72 h peri-operatively. RESULTS:The hemodynamic and cardiac effects of 6% HES were superior to 20% albumin.HES reduced disturbances in blood coagulation, blood loss, and blood use as compared to albumin. Volume therapy with HES and albumin improved patient outcomes.Use of HES resulted in a significant cost reduction compared to albumin. CONCLUSIONS:Volume replacement with 6% HES and 20% albumin in surgery over 72 h peri-operatively improved hemodynamic parameters and oxygen transport to normal values.HES provides a cost-effective alternative to albumin in surgery with improved efficacy and safety.
Blood Coagulation ; Gases ; Hemodynamics ; Humans ; Orthopedics ; Oxygen

BACKGROUND:This study was designed to compare hydroxyethylstarch (HES) to albumin in high-risk surgery patients infused over 72 h peri-operatively; hemodynamic changes, oxygen transport parameters, blood gases, blood coagulation, blood loss, blood use, outcome, and costs were compared. METHODS:High-risk surgical patients undergoing high-risk abdominal, cranial, and orthopaedic surgery were treated with 6% HES (130/0.4; n = 41) or 20% albumin (n = 19).The goal of volume therapy was to maintain a normal cardiac index (CI; 3.0 L/min/m2) over 72 h peri-operatively. RESULTS:The hemodynamic and cardiac effects of 6% HES were superior to 20% albumin.HES reduced disturbances in blood coagulation, blood loss, and blood use as compared to albumin. Volume therapy with HES and albumin improved patient outcomes.Use of HES resulted in a significant cost reduction compared to albumin. CONCLUSIONS:Volume replacement with 6% HES and 20% albumin in surgery over 72 h peri-operatively improved hemodynamic parameters and oxygen transport to normal values.HES provides a cost-effective alternative to albumin in surgery with improved efficacy and safety.
Blood Coagulation ; Gases ; Hemodynamics ; Humans ; Orthopedics ; Oxygen

The changes of blood gases, K and glucose levels of ACD banked blood according to the days of storage were observed. The samples were taken from the blood stored in the blood bank of Dong San Medical Center just before transfusing them in to patients. The results were as follows: 1) The pH value of one day stored blood was 6,720+/-0.0035. The PH gradually decreased according to the number of days it was stored which was significant statistically(p<0.05). 2) The O2 tension of one day stored blood was 24.1+/-3.25 torr and there was no significant changes in O2 tension according to the storage time. 3) The K level of one day stored blood was 5.7+/-0.5mg and this increased gradually as the storage time increased which was statistically significant(p<0.001). 4) The CO2 tension of one day stored blood was 133.1+/-6.4 torr and this increased according to the days of storage but it was not significant statistically. 5) The blood glucose level of one day stored blood was 338.5+/-0.5mg% and there was no significant increase or decrease as the storage time increased.
Blood Banks ; Blood Glucose ; Gases ; Glucose* ; Humans ; Hydrogen-Ion Concentration

The most important factor in clinical development of respiratory care has been the clinical availabiTity of blood gas and pH measurement and it is important to get the accurate values of those. There can be an error to get the value of PCO2, PO2 and pH by dilutional effect of liquid-Naheparin that is usally used as an anticoagulant. We compared values of 20 arterial blood gases sampled with 1 cc plastic syringe utilizing liquid-Na-heparin with those ones sampled with 1 cc arterial blood gas kits which were pre-filled with dry-Lithium-heparin. The results were as follows; 1) There are no difference in values of PO2 and pH between two groups. 2) The value of PCO2 sampled with 1 cc plastic syringe utilizing liquid-Na-heparin is 1.62 torr less than the value of that with 1 cc arterial blood gas kits which were pre-filled with dry-Lithium-heparin (p<0.05).
Blood Gas Analysis* ; Gases ; Hydrogen-Ion Concentration ; Plastics ; Syringes*

BACKGROUND: Platelets (PLTs) stored in platelet additive solution (PAS) presents potential benefits in clinical use by reducing the risk of several plasma-associated adverse transfusion reactions and more plasma may be recovered for fractionation. In this study, we compared in vitro characteristics of apheresis PLTs stored in CompoSol PS (Fenwal, Lake Zurich, IL, USA), InterSol (Fenwal, Lake Zurich, IL, USA), SSP+ (MacoPharma, Tourcoing, France), T-PAS+ (Terumo BCT, Lakewood, CO, USA), or plasma to evaluate the effectiveness of PAS. METHODS: PLTs were collected two times by apheresis from 12 healthy volunteers in a study comparing four kinds of PASs with 35% autologous plasma and 100% plasma-stored apheresis PLTs. The parameters of PLTs, including PLT counts, pH, PLT activation markers, blood gases, and metabolic variables were assessed up to 7-day. RESULTS: The results of in vitro assay including PLT concentration, mean PLT volume, pH, and blood gases for PLTs in four kinds of PASs were similar to those in 100% plasma PLTs. All units had Day 5 pH greater than 6.2. In vitro quality rating results, PLTs in T-PAS+ had a rating of 5, 4 for CompoSol PS, 2 for SSP+, 1 for InterSol, and 2 for plasma on Day 5. CONCLUSION: Partial replacement of plasma with CompoSol PS, SSP+, or T-PAS+ in PLTs showed better or equivalent quality and preservability of PLTs compared to PLTs in 100% plasma. The use of PAS for storage of PLTs in clinical practice may have an advantage as PAS-stored PLTs have a reduced volume of plasma.
Blood Component Removal* ; Blood Group Incompatibility ; Blood Platelets* ; Gases ; Healthy Volunteers ; Hydrogen-Ion Concentration ; Lakes ; Plasma

Many studies have undertaken to determine the optimal volume of heparin diluted blood so- lutions to be aspirated from known internal volume of the arterial extension tube before blood sampling, in order to achieve acceptable blood gas values. This study was investigated the optimal volume of heparin diluted blood to be aspirated from various kinds of extension tube which volume is unknown. Blood gases were measured in samples of the radial artery or superior vena cava blood taken from 20 anesthesized patients who were taking elective or emergency surgery with indwelling catheter. Authors used 4 kinds of extension tube. There were 120 cm Cobe extension tube, 140 cm Cobe extension tube, 60 cm extension tube using I.V. set and 120 cm extension tube using I.V. set. Each of tubes was applied to five patients. Five blood gas samples were taken after withdrawing heparin diluted flush solution and blood from each extension tube. The withdrawing blood amounts is serially 0.5, 1.0, 1.5, 2.0, and 2.5 times of volume of each extension tube. And then another blood sample was taken from the 3-way stop-cock at proximal site of Cobe or LV. extension tube. Because this last sample was not diluted with heparin diluted flush solution, author assumed this blood gas values to be control group. Blood gas values of each samples were compared with control group. The difference between sample 3 and 4 was statistically significant(p<0.05) in case of small inner volume of extension tube. The difference between sample 4 and 5 was stastistically significant(p<0.05) in case of large inner volume of extension tube. So, authors concluded that as follows: If the inner volume of extension tube is small(volume <4 ml), blood gas samples should be taken after withdrawing 2.0 times of the inner volume of extension tube, however if the inner volume of extension tube is large(volume>4ml), blood gas samples should be taken after withdrawing 2.5 times of the inner volume of extension tube.
Blood Gas Analysis ; Catheters, Indwelling ; Emergencies ; Gases ; Heparin* ; Humans ; Radial Artery ; Vena Cava, Superior

PURPOSE: We aimed to investigate the cardiopulmonary effects of pressurized cement insertion in elderly patients undergoing cemented hip hemiarthroplasty. MATERIALS AND METHODS: We conducted a randomized prospective study on elderly patients undergoing cemented hip hemiarthroplasty. Patients were divided into pressurized and non-pressurized groups based on the pressure application during cement insertion. We measured mean arterial blood pressure (MAP), systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), arterial blood gases and serotonin concentration in blood. These variables were measured before bone cement insertion, and 3 and 5 minute after insertion. They were also measured immediately and 15 minutes after reduction. RESULTS: In cemented hip hemiarthroplasty, there were no significant change in MAP (P=0.92), SBP (P=0.85), DBP (P=0.98), HR (P=0.97) and serotonin concentration over time. There were no statistically significant difference between the two groups in MAP, SBP, DBP, HR, PO2, PaCO2, SaO2 and serotonin concentration, though three minutes after cement insertion, both groups showed decreases in SBP, DBP and MBP. CONCLUSION: The pressurization method in cemented hip hemiarthroplasty was not found to be related with development of bone cement syndromes in elderly patients.
Aged ; Arterial Pressure ; Blood Pressure ; Gases ; Heart Rate ; Hemiarthroplasty* ; Hip* ; Humans ; Prospective Studies* ; Serotonin

Although heparin solution is widely used as an anticoagulant in blood gas analysis, alterations in blood gas measurements may occur when small sample volumes are diluted by heparin. Cook pressure tubing for infants and children and Gould pressure line for adults were applied to each of 10 adult patients whose cardiovascular fuction was normal. Arterial blood gases were measured serially after withdrawing 2,4,6,8,10 and 12 ml of flus-blood solutions from the Gould pressure connecting tubing, and 1,2,3,4,5 and 6 ml from the Cook pressure line, which were connected to a transducer through a 3way stopcock. In the Gould pressure tubing, the pH was unchanged from sample 2 and PaCO2, HCO3- and base excess were unchanged from sample 3. PaO2 did not change between the samples. In the Cook pressure line, the pH and base excess were unchanged from sample 2 and PaCO2, HCO3- and PaO2 from sample 3. We conclude that arterial blood should be withdrawn in volumes of at least 4ml by the Gould pressure connecting tubing and 3ml by the Cook pressure line to obtaine accurate results in blood gas analysis.
Adult ; Blood Gas Analysis ; Child ; Gases ; Heparin ; Humans ; Hydrogen-Ion Concentration ; Infant ; Transducers

A method for one-lung anesthesia in which a 14 Fogarty emboiectomy catheter is used to occlude a main bronchus is described. The method is quick, simple, effective and reliable. It eliminates most of the problems which occurs with the standard technique of using a double-lumen cuffed endotracheal tube. During one-lung mannual ventilation, anesthesia was maintained with ketamine I.V. infusion and pancuronium. Before and after one-lung anesthesia, halothane-nitrous oxide-oxygen and pancuronium were used. No significant problems regarding blood pressure, pulse rate, EKG and arterial blood gases were encountered in 3 lung cancer cases who had a pneumonectomy, a lung biopay and a left lower lobectomy.
Anesthesia* ; Blood Pressure ; Bronchi ; Catheters* ; Electrocardiography ; Gases ; Heart Rate ; Ketamine ; Lung ; Lung Neoplasms ; Pancuronium ; Pneumonectomy ; Ventilation