【Objective】 To explore the risk factors that affect the outcome of testicular torsion in patients with testicular resection, to provide ideas for clinical management. 【Methods】 The clinical data of 117 patients with testicular torsion treated in our hospital during Jan.1, 2012 and Mar.1, 2023 were retrospectively analyzed, 43 of whom underwent testicular detorsion and orchidopexy, and 74 underwent orchiectomy.The correlation between preoperative inflammatory and coagulation-related indicators, testicular torsion angle, TWIST score and orchiectomy was analyzed with univariate analysis.The independent risk factors for testicular torsion patients with testicular resection as the outcome were analyzed with binary logistic regression.The predictive value of each factor for orchiectomy was assessed with receiver operating characteristic (ROC) curve. 【Results】 Binary logistic regression analysis indicated that long duration of onset (OR=1.841, P=0.036), large torsion angle (OR=1.005, P=0.016), high TWIST score (OR=2.225, P=0.003) and elevated FIB level (OR=2.489, P=0.049) were independent risk factors for testicular torsion patients with testicular resection as the outcome.ROC curve analysis showed that the best cut-off value of the above 4 factors to predict orchiectomy were 1.75 days, 225°, 3.5 and 3.155 g/L; the area under the ROC curve (AUC) were 0.893, 0.718, 0.812 and 0.770, respectively. 【Conclusion】 The duration of onset, torsion angle, TWIST score, and FIB level are independent risk factors for testicular torsion patients with testicular resection as the outcome, and these indicators have certain predictive value.

【Objective】 To investigate the clinicopathological features and key points of diagnosis and treatment of malignant perivascular epithelioid cell tumor (PEComa) to increase awareness of the disease. 【Methods】 The clinicopathological data of 2 patients with malignant PEComa treated in our hospital were retrospectively analyzed, and relevant literatures were reviewed. 【Results】 Both patients were male, aged 53 and 16 years, respectively.The sites of occurrence were in the retroperitoneum and pelvis, respectively.Both tumors were resected surgically, and the diagnosis was confirmed with postoperative pathology.Under the microscope, the tumor tissue of one patient was mainly composed of smooth muscle-like cells, and that of the other patient was composed of epithelioid cells, both showing pathological mitotic images and expressing HMB45, Melan-A, SMA and CD34, no tumor recurrence or metastasis was observed during the follow-up.The literatures collected involved 15 patients with retroperitoneal or pelvic PEComa, including 3 males and 12 females, of which 9 were malignant.The clinical manifestations were abdominal pain, bloating, or lower back pain.Some cases were detected during physical examinations. 【Conclusion】 Malignant PEComa is difficult to be diagnosed before surgery and easy to be misdiagnosed.The confirmed diagnosis depends on the postoperative pathological results.The preferred treatment is complete resection of tumor.Long-term follow-up is needed.