Objective To analyze the impact factors of early postoperative epilepsy.Methods Retrospective analysis the 142 clinical data of meningioma operation patients.Study the influence factors of early postoperative epilepsy by single factor analysis combined with multivariate analysis.Results Of multivariate analysis,age,preoperative epilepsy,tumor recurrence,tumor edema,movement disorders,supratentorial neoplasms,tumor diameter in the early postoperative epilepsy risk factors,preoperative prophylactic medication,postoperative prophylaxis were the protective factors(x2 =6.139.4.358,5.119,6.121,5.173,4.879,5.452,6.189,5.563,all P ＜0.05).Conclusion The corresponding prevention measures,prevention and treatment should be taken for early epilepsy.