Objective:To explore the current status of postoperative life meaning in patients with colorectal cancer, and analyze its influencing factors, so as to provide a basis for clinical intervention.Methods:From May to October 2020, 90 cases of postoperative colorectal cancer patients in the First Affiliated Hospital of Zhengzhou University were selected as the research object by convenience sampling. The cross-sectional survey was conducted with the General Information Questionnaire, Cancer Patient Life Meaning Scale and Social Support Rating Scale. Multivariate linear regression analysis was used to analyze the influencing factors. A total of 90 questionnaires were distributed in this survey, and 83 valid questionnaires were returned.Results:Among 83 patients with colorectal cancer, the total score of the Cancer Patient Life Meaning Scale was (55.01±13.43) , and the two dimensions with low scores were life goals (2.13±0.47) and acceptance and adaptation (2.04±0.44) . Pearson correlation analysis showed that the total score and dimension scores of the Social Support Rating Scale of colorectal cancer patients were positively correlated with the total score of the Cancer Patient Life Meaning Scale with statistical differences ( P<0.05) . The results of multiple linear regression analysis showed that the influencing factors of the life meaning of patients with colorectal cancer were age, family monthly income, disease stage, stoma and social support ( P<0.05) . Conclusions:The life meaning of patients with colorectal cancer is at a moderately lower level. Clinical medical and nursing staff should pay attention to patients with young age, poor income, high disease stages and stoma, and enhance their level of social support, so as to increase the life meaning of colorectal cancer patients and ultimately improve their quality of life.

Objective To investigate the application value of hepatectomy via anterior approach in the surgery of primary liver cancer. Methods Clinical data of 138 patients with primary liver cancer undergoing hepatectomy in Sun Yat-sen Memorial Hospital and Lingnan Branch, the Third Afifliated Hospital of Sun Yat-sen University from June 2011 to June 2014 were retrospectively analyzed. There were 97 males and 41 females, aged 36 to 87 years with a median age of 52 years. The informed consents of all patients were obtained and the local ethical committee approval had been received. The patients were divided into the anterior approach hepatectomy group (anterior group, n=63) and traditional approach hepatectomy group (traditional group, n=75). Preoperative general data, intra-, post-operative parameters of two groups were compared using t test or Chi-square test. Results In the anterior group, the percentage of patients with Child-Pugh liver function grade B and C, multiple tumors and tumor diameter>10 cm was 73%(46/63), 44%(28/63) and 16%(16/63) respectively, which were signiifcantly higher compared with 37%(28/75), 17%(13/75) and 5%(4/75) in the traditional group (χ2=20.444, 12.051, 8.144;P<0.05). In the anterior group, the average intraoperative blood loss, transfusion volume of plasma and red blood cells were (428±17), (470±14) and (300±7) ml, which were signiifcantly lower compared with (517±11), (630±15) and (420±11) ml in the traditional group (t=-6.097,-2.927,-8.928;P<0.05). The rate of postoperative complications in anterior group was 10%(6/63), which was signiifcantly lower compared with 17%(13/75) in the traditional group (χ2=1.759, P<0.05). Conclusion For patients with poor liver function, multiple and large tumors, hepatectomy via anterior approach is a preferential surgical procedure rather than the traditional approach hepatectomy.

Objective To investigate the clinical value of magnetic resonance cholangiopancreatography (MRCP) in the preoperative evaluation of patients with biliary calculus. Methods Clinical data of 70 patients with biliary calculus in Sun Yat-sen Memorial Hospital and the Third Afifliated Hospital of Sun Yat-sen University from June 2012 to June 2013 were retrospectively analyzed. There were 38 males and 32 females with age ranging from 18 to 87 years old and the median age of 52 years old. The informed consents of all patients were obtained and the ethical committee approval was received. The patients underwent ultrasound examination and MRCP before operation. The surgical procedures were cholecystectomy+bile duct exploration and the intraoperative exploration result was the gold standard of diagnosis for biliary calculus and biliary tract variations. The detectable rate of biliary calculus and biliary tract variations by two methods were compared using Chi-square test and Fisher's exact probability test. Results The detectable rate of gallstones was 93%(62/67) by ultrasound and was 79%(53/67) by MRCP, where signiifcant difference was observed (χ2=4.968, P<0.05). The detectable rate of common bile duct stones was 61%(17/28) by ultrasound and was 86%(24/28) by MRCP, where signiifcant difference was observed (χ2=4.462, P<0.05). The detectable rate of the left and right hepatic duct stones was 2/5 by ultrasound and was 4/5 by MRCP, where no signiifcant difference was observed (P>0.05). The detectable rate of intrahepatic bile duct stones was 36%(4/11) by ultrasound and was 73%(8/11) by MRCP, where no signiifcant difference was observed (P>0.05). The detectable rate of biliary tract variations was 2/8 by ultrasound and was 7/8 by MRCP, where signiifcant difference was observed (P<0.05). Conclusions MRCP is superior to ultrasound examination in the detection of common bile duct stones and biliary tract variations. It can be a common practice in the preoperative evaluation of patients with biliary calculus when circumstances allow.