CMTM3 and CMTM7 are two newly discovered anti-oncogenes,which exist in various kinds of organs and tissues and having multiple biological functions including cell proliferation,differentiation,migration,and apoptosis. Recently,it has been shown that these two anti-oncogenes have closely relationship with gastrointestinal tract tumor,which can inhibit the growth of esophageal,gastric,and colorectal cancer. In this review article,the advances in study of the relationship between these two anti-oncogenes and tumors of gastrointestinal tract were summarized.

Objective To assess the imaging characters and clinical applications of triphasic spiral computer tomography(CT) scanning in ureteral lesions.Methods We analyzed of 76 consecutive cases of clinically evidenced ureteral lesions using the cross-sectional images and CTU derived from triphasic spiral CT scanning retrospectively.Results Twetny-four cases of 76 ureteral lesions patients were diagnosed as ureteral tumor,resulting in severe urinary tract obstruction.The shape,size,number,regional ureter wall inflammatory infiltration of visible mass were verified as well.Twetny-six cases were caused by ureteral stones.The "edge" sign was shown clearly.Ten cases were ureteral inflammation,characterized by different ureteral wall thickening and enhancement feature.Eight cases were ureteral tuberculosis that secondary to renal tuberculosis.Uneven ureteral wall thickening,stiffness and mild to moderate density were shown in CT scanning.Ureteral congenital malformations were found in 3 patients.The other five cases were caused by exogenous factors.CT scanning could identify the mass general profile.Conclusion Triphasic spiral CT scanning plays an important role in ureteral lesions diagnosis and differentiation from other similar diseases.

Objective To assess the imaging characters and clinical applications of triphasie spiral computer tomography (CT) scanning in ureteral lesions. Methods We analyzed of 76 eonseeutive eases of elinieaUy evidenced ureteral lesions using the cross - sec-fional images and CTU derived from triphaaie spiral CT scanning retrospectively. Results Twetny - four cases of 76 ureteral lesions pa-tients were diagnosed as ureteral tumor, resulting in severe urinary tract obstruction. The shape, size, number, regional ureter wall in-flammatory infiltration of visible mass were verified as well. Twetny- six cases were caused by ureteral stones. The "edge" sign was shown clearly. Ten cases were ureteral inflammation, characterized by different ureteral wall thickening and enhancement feature. Eight cases were ureteral tuberculosis that secondary to renal tuberculosis. Uneven ureteral wall thickening, stiffness and mild to moderate densi-ty were shown in CT scanning. Ureteral congenital malformations were found in 3 patients. The other five cases were caused by exogenous factors. CT scanning could identify the mass general profile. Conclusion Triphasic spiral CT scanning plays an important role in ureteral lesions diagnosis and differentiation from other similar diseases.

Objective To investigate the role of RhoA and Rho kinase system in the onset of labor. Methods Forty term pregnant women, who delivered through cesarean section at the Xiangya Second Hospital of Central South University from February 2007 to November 2007, were selected and divided into 2 groups: 20 in labor group and 20 in non-labor group. Another 20 non-pregnant women undergoing hysterectomy due to cervical intraepithelial neoplasia were chosen as the control. Real-time fluorescence quantitative RT-PCR and western blot were applied to detect the expression RhoA and ROCKⅠ mRNA and protein in uterine smooth muscle tissue and the correlation between the mRNA and protein expression of RhoA and ROCKⅠ were analyzed. Results (1) The mRNA expressions of both RhoA and ROCKⅠ were detected in all groups, and higher levels were found in the labor group than in the non-labor group and the control [RhoA mRNA: (3.51±0.56)×10-3 vs. (2.75±0.52)×10-3 and (2.11±0.54)×10-3; ROCKⅠ mRNA: (4.07±0.66)×10-3 vs. (2.71±0.52)×10-3 and(2.01±0.23)×10-3, P<0.01]. (2) RhoA and ROCKⅠ proteins were also identified in all three groups, and the expressions in the labor and non-labor group were higher than those of the control (RhoA protein: 0.72±0.23 and 0.64±0.17 vs. 0.46±0.15; ROCKⅠ protein: 0.56±0.14 and 0.42±0.16 vs. 0.29±0.08, P<0.01). (3) The expression of RhoA mRNA and ROCKⅠ mRNA were positively correlated in each of the three groups (r=0.73,P<0.01), and the same was found in the expression of RhoA protein and ROCKⅠ protein (r=0.37,P<0.01). Conclusion The increased expression of RhoA and Rho kinase may play an important role in the initiation of labor.

To study the clinicopathological features of breast carcinoma with responsive granuloma. MethodsFive cases of breast carcinomas with responsive granuloma were investigated by morphological observation. ResultsAll the five patients had noncaseating epithelioid granulomas. Multinucleated giant cells, predominantly of Langhans type, were present in granulomas. The granulomas were restricted to the carcinoma, and no responsive granulomas were evident in the regional lymph nodes. None of the patients had clinical evidence of systemic granulomatous disease. ConclusionDifferential diagnosis of breast carcinoma with responsive granuloma should include the carcinoma with osteoclast-like giant cells, metaplastic the carcinoma with osteoclastic giant cells, granulomatous lobular mastitis, stromal responsive giant cells, and carcinoma with sarcoidosis or tuberculosis of the breast.

Objective:To compare performances of Wechsler Memory Scale(WMS)and Clinical Memory Scale(CMS),to explore applicability of WMS and CMS in the different degree traumatic brain injured patients.Methods:206 patients were tested with WMS and 300 with CMS,and completed clinical diagnosis for all,to compare the performances.Results: ①There was no significant differences in the MQ between the two groups in the normal、marginal memory impairment, there were significant differences in the mild memory impairment.②There were remarkable variance between the MQ and the clinical diagnosis,WMS was even more variant.Conclusion:①There is similar outcome between WMS and CMS in the patients with normal、marginal memory impairment,CMS shows more applicable in the patients with more severe mem- ory impairment.②It is not correct to diagnose memory defect degree with MQ without more clinical information.

Objective To observe the apoptosis of neuron and protein kinase B (Akt) expression after intracerebral hemorrhage (ICH)in rats, and investigate the interference effect and mechanism of ?-aeacine sodium on ICH injury.Methods All Sprague - Dawley male rats were randomly divided into normal group, pseudo -operation group,model group and therapeutic group treated with ?-sodium aeacine.The latter three groups were divided into five subgroups respectively :6 h,12h,1d,3d and 7d.ICH models were performed by injection Ⅶ type collagenase into the the right globus pallidus.By the methods of in situ terminaldeoxynucleotidyl transferase- mediated dUTP nick end labeling (TUNEL) and immunohistochemistry, The dynamic changes of apoptosis and the expression of AKt protein were observed in the damaged cortex.Results TUNEL-positive cells appeared at 6h after collagenase injection in the model group and the expression of AKt increased at 12 h.They reached their peak at 3rd day, and were still present during 1 week. The numbers of TUNEL-positive cells in 1 d, 3 d, 1 week after ICH decreased markerly in treatment group than those of in model group ( P

Objective To explore the experiences in nursing children with snoring in the peri-operative period. Methods Five hundred and six children with snoring in the affiliated Shengjing Hospital of China Medical University from January 2013 to December 2014 were enrolled in the study. The clinical data of all children and the nursing measures were analyzed retrospectively during the peri-operative periods to look into psychological nursing, preoperative evaluation and nursing instructions before the surgeries and keeping respiratory tract un-obstructed, bleeding observation, pain nursing and infection prevention. Results The 506 children underwent tonsillectomy with adenoidectomy or simple adenoidectomy . Two patients had hemorrhage after operation and hemostasis was done successfully by surgeries . Conclusion The nursing measures including psychological nursing , preoperative evaluation and health instructions can be critical for ensuring the successful operation and keeping the respiratory tract unobstructed , infection prevention, bleeding observation and pain nursing can be helpful for reducing the postoperative complications and enhance the quality of life.

Objective To assess the value of ECG in the diagnosis of acute pulmonary embolism (APE). Methods Twenty-eight patients with APE were included,with mean age of 56?16,and PaO 2,electrocardiogram (ECG),echocardiogram (ECHO) and ventilation/perfusion lung scan were performed. Results 96.4% patients had risk factors,and had different degree of hypoxia. 92.9% patients had ECG changes,most of whom (57.1%) showed ST-T changes. The ventilation/perfusion lung scan confirmed the diagnosis. Conclusion Considering the clinical symptom,arterial blood gas analysis,the early changes of ECG are useful in the diagnosis of the APE.

Objective:Hepatocyte growth factor(HGF) speculated to be an endothelial-specific growth factor which protects or repaire the vascular endothelial cells. To test the serum HGF level might be elevated in response to hypertension-induced endothelial cell damage, we measured serum HGF concentrations in normotensive and hypertensive subjects without liver, kidney and other complications.Methods:Eighteen male hypertensive patients and thirteen male normotensive subjects were recruited. All antihypertensive agents were stopped for 2 weeks before the study. The serum HGF concentrations were measured by a specific enzyme-linked immunosorbent assay (ELISA). Results:Serum HGF concentrations were 0.32±0.13 ng/ml in normotensive subjects and 0.37±0.27 ng/ml in hypertensive patients. No significant difference between the two groups(P>0.05) was found. Systolic, mean and diastolic blood pressure did not show any correlation with serum HGF concentrations.Conclusions:This study showed that serum HGF levels did not be increased in male patients with mild to moderate hypertension. Although local HGF is produced rapidly because of the damage of endothelial cells by high blood pressure, the circulating level of HGF did not represent the local changes of HGF production.