We present a case of ganglioneuroma arsing from the sympathetic ganglia in the pelvic cavity.
Ganglia, Sympathetic ; Ganglioneuroma*

No abstract available.
Ganglioneuroma* ; Intestine, Large

No abstract available.
Adrenal Glands* ; Ganglioneuroma* ; Hyperplasia*

Ganglioneuromas (GNs) are benign tumors that originate from neural crest cells, composed mainly of mature ganglion cells. These tumors, which are usually hormonally silent, tend to be discovered incidentally on imaging tests and occur along the paravertebral sympathetic chain, from the neck to the pelvis and occasionally in the adrenal medulla. Rarely, GNs secrete catecholamines.1 Adrenal GNs occur most frequently in the fourth and fifth decades of life, whereas GNs of the retroperitoneum and posterior mediastinum are usually encountered in younger adults.2 Adrenal GNs are commonly hormonally silent and asymptomatic; even when the lesion is of substantial size.3We report an incidentally detected asymptomatic case of an adrenal ganglioneuroma with mildly elevated urinary catecholamine levels in an elderly male. After preoperative alpha blockade, the patient underwent open right adrenalectomy. Upon microscopic examination, the right adrenal mass proved to be a ganglioneuroma, maturing type and the immunohistochemistry examination showed immunoreactivity to synaptophysin, chromogranin, and CD 56, while S100 was strongly positive at the Schwannian stroma. Following resection, catecholamine levels normalized, confirming the resected right adrenal ganglioneuroma as the source of the catecholamine excess. This case represents a rare presentation of catecholamine-secreting adrenal ganglioneuroma in the elderly.
Adrenal Glands ; Catecholamines ; Ganglioneuroma

Ganglioneuroma is a rare benign tumor which originates in the neural crest, and is found along the path of the sympathetic chain, from the base of the skull to the pelvic cavity. Due to the slow growth of this type of tumor, it may be detected incidentally, or detected by virtue of the attendant pressure effects on adjacent structures. We report one case of ganglioneuroma arising in the pelvic cavity.
Ganglioneuroma ; Neural Crest ; Skull ; Virtues

No abstract available.
Cerebellum ; Ganglioneuroma* ; Hamartoma Syndrome, Multiple

No abstract available.
Ganglioneuroma* ; Lymph Nodes* ; Neoplasm Metastasis*

Authors report a rare case of dumb-bell ganglioneuroma in the neck of a four-year-old child. The mass was in the left anterior neck and grew slowly over several years. Neurological deficits. Cervical spine X-rays showed an enlargement of intervertebral foramens and widening of interpedicular distances at lower cervical level. The surgery was performed at different stages for a total removal of the intra and extraspinal masses.
Child* ; Ganglioneuroma* ; Humans ; Neck* ; Spine

The adrenal ganglioneuroma was rare benign tumor that arise from mature sympathetic ganglion cells, located within the substance of the adrenal medulla or along the sympathetic chain. It may secrete catecholamines, represent endocrine symptoms. Nonfunctional growths remain silent until they reach large size. They are usually discovered incidentally. Herein we report a case of left adrenal ganglioneuroma that was incidentally discovered.
Adrenal Medulla ; Catecholamines ; Ganglia, Sympathetic ; Ganglioneuroma*

Recent increased use of ultrasonography and computed tomography have led to the problem of adrenal incidentaloma, an asymptomatic adrenal mass discovered during investigation of some other problem. Treatment of these tumors, described as incidentalomas is controversial and the most important question in regard to such tumors is whether or not there is a need for surgical exploration as the final diagnostic measure because benign lesion of the adrenal gland is much more common than malignant one. And there exist a need to accumulate better information related to this entity in order to establish more reliable guideline for patient management when incidentaloma is encountered. Herein, we report a case of incidentally found adrenal ganglioneuroma in 14-year old boy who underwent surgical exploration.
Adolescent ; Adrenal Glands ; Ganglioneuroma ; Humans ; Male ; Ultrasonography