No abstract available.
Ganglioglioma*

The desmoplastic infantile ganglioglioma is very rare cerebral tumor. It has been known to be characterized by its voluminious size, intense desmoplasia and the frequent presence of astrocytic and ganglioglionic differentiation. Also, It is usually presented in infantile period and predilected in the frontal and parietal lobes. We treated a huge desmoplastic infantile ganglioglioma(8?7?6cm) on the right frontotemporo-parietal area with only gross total resection. It includes solid mass & several cysts and shows the areas of the proliferation of spindle cells exhibiting storiform pattern in dense desmoplastic stroma and the areas composed of spindle shaped glial component.
Ganglioglioma* ; Parietal Lobe

No abstract available.
Ganglioglioma* ; Neoplasms, Neuroepithelial ; Neuroblastoma ; Prognosis

Spinal cord ganglioglioma is an extremely rare tumor. Authors present a 6-year old boy who had a holocord ganglioglioma with a long history of kypho-scoliosis. The mass was located entirely in the spinal cord and mixed cystic and solid with variable consistencies. The color was grayish purple-yellow in soft part, and pale yellow-white in scirrhoid part. It was not well demarcated by surrounding normal spinal cord in major parts.
Child ; Ganglioglioma* ; Humans ; Male ; Spinal Cord

Desmoplastic infantile ganglioglioma is an uncommon variety of ganglioglioma that shows evidence of glial andganglionic differentiation accompanied by an extreme desmoplastic reaction. A 16-month-old girl was ad-mitted witha six-day history of left hemiparesis. MR imaging demonstrated a large multiseptated cystic mass, with a solidportion, in the white matter of the right frontotemporoparietal lobe. After contrast injections, the solid portionwas clearly enhanced. The presence of desmoplastic infantile ganglioglioma was confirmed by surgical resection. Wedescribe the characteristic radiologic and pathologic features of desmoplastic infantile ganglioglioma, andinclude a a review of the literature.
Female ; Ganglioglioma* ; Humans ; Infant ; Magnetic Resonance Imaging ; Paresis

Gangiogliomas are rare tumors, primarily seen in patients under the age of 30 years. They occure least commonly in the spinal cord. We present a 17-year-old girl who harbored an intramedullary conus ganglioglioma.
Adolescent ; Conus Snail* ; Female ; Ganglioglioma* ; Humans ; Spinal Cord

OBJECTIVE: The incidence of leptomeningeal dissemination from malignant glioma is rare, so the clinical features of this are not well documented yet. We attempted to determine the clinical features of leptomeningeal dissemination from malignant gliomas. METHODS: We retrospectively analyzed 11 cases of leptomeningeal dissemination of malignant glioma, who were treated at our institution between 2006 and 2009. We investigated the clinical features of these patients by considering the following factors : tumor locations, the events of ventricular opening during surgery and the cerebrospinal fluid (CSF) profiles, including the cytology. RESULTS: The group was composed of 9 males and 2 females. The histological diagnosis of their initial intracranial tumors were 4 primary glioblastoma, 3 anaplastic astrocytoma, 1 anaplastic oligoastrocytoma, 2 ganglioglioma and 1 pleomorphic xanthoastrocyotma with anaplastic features. The mean age of the patients at the time of the initial presentation was 42.8+/-10.3 years. The mean time between surgery and the diagnosis of spinal dissemination was 12.3+/-7.9 (3-28) months. The mean overall survival after dissemination was 2.7+/-1.3 months. All our patients revealed a history of surgical opening of the ventricles. Elevated protein in the CSF was reported for eight patients who had their CSF profiles checked. CONCLUSION: We propose that in the malignant gliomas, the surgical opening of ventricles can cause the spinal leptomeningeal dissemination and the elevated protein content of CSF may be a candidate marker of leptomeningeal dissemination.
Astrocytoma ; Female ; Ganglioglioma ; Glioblastoma ; Glioma ; Humans ; Incidence ; Male ; Retrospective Studies

We present a case of ganglioglioma in the cerebellar vermis. A 2-year-old boy presented with symptoms and signs of raised intracranial pressure and the physical examination revealed large head and developmental delay. Magnetic resonance image demonstrated a hypointense mass in the cerebellar vermis on T1-weighted image with heterogeneous enhancement after gadolinium administration, mimicking a malignant tumor. A gross total resection was performed and pathologic findings demonstrated a ganglioglioma. There was no evidence of recurrence of the tumor during 16 months follow up period.
Cerebellum ; Child, Preschool ; Follow-Up Studies ; Gadolinium ; Ganglioglioma ; Head ; Humans ; Intracranial Pressure ; Male ; Physical Examination ; Recurrence

Gangliogliomas are benign tumors, composed of neoplastic astrocytes and nerve cells. They are rare, account for 0.4-6.25% of all primary central nervous system neoplasms. Gangliogliomas affect predominantly infants or young adults. Gangliogliomas are preferentially encountered supratentorially, predominantly affecting the temporal lobe. Spinal gangliogliomas affect predominantly the cervical spinal cord. We report a case of cervical ganglioglioma which was successfully removed surgically, with a review of literature.
Astrocytes ; Central Nervous System Neoplasms ; Ganglioglioma* ; Humans ; Infant ; Neurons ; Spinal Cord ; Temporal Lobe ; Young Adult

PURPOSE: Dysembryoplastic neuroepithelial tumor (DNET) is a newly described, pathologically benign tumor arising within the supratentorial cortex. We reviewed the MR appearance of five patients with DNET, emphasizing the clinical and radiologic features. MATERIALS AND METHODS: MR images in the five patients (three male and two female) with a history of epileptic seizure and pathologically-proven DNET were retrospectively reviewed. We analyzed the location, configuration, signal intensity, contrast enhancement, vasogenic edema and calcifications of these tomors. RESULTS: The tumors were located mainly in the cortical to subcortical area with very little perifocal mass effect on MR imaging. They were essentially hypointense on T1-weighted imaging, and showed a hyperintense well circumscribed mass on T2-weighted imaging and a thick gyrus-like configuration was retained within the lesions. On contrast enhanced study, focal nodular enhancement was seen in one patient, and multifocal nodular enhancement in two. CONCLUSION: DNET is rare benign tumor resulting in often medically intractable epileptic seizure and shows a characteristic gyriform configuration, well-described lobular tumor margins and sometimes multifocal nodular enhancement. These radiologic features may aid in differentiating DNET from ganglioglioma and other gliomas.
Edema ; Epilepsy ; Ganglioglioma ; Glioma ; Humans ; Magnetic Resonance Imaging ; Male ; Neoplasms, Neuroepithelial* ; Retrospective Studies