No abstract available.
Ganglioglioma*

The desmoplastic infantile ganglioglioma is very rare cerebral tumor. It has been known to be characterized by its voluminious size, intense desmoplasia and the frequent presence of astrocytic and ganglioglionic differentiation. Also, It is usually presented in infantile period and predilected in the frontal and parietal lobes. We treated a huge desmoplastic infantile ganglioglioma(8?7?6cm) on the right frontotemporo-parietal area with only gross total resection. It includes solid mass & several cysts and shows the areas of the proliferation of spindle cells exhibiting storiform pattern in dense desmoplastic stroma and the areas composed of spindle shaped glial component.
Ganglioglioma* ; Parietal Lobe

No abstract available.
Ganglioglioma* ; Neoplasms, Neuroepithelial ; Neuroblastoma ; Prognosis

Spinal cord ganglioglioma is an extremely rare tumor. Authors present a 6-year old boy who had a holocord ganglioglioma with a long history of kypho-scoliosis. The mass was located entirely in the spinal cord and mixed cystic and solid with variable consistencies. The color was grayish purple-yellow in soft part, and pale yellow-white in scirrhoid part. It was not well demarcated by surrounding normal spinal cord in major parts.
Child ; Ganglioglioma* ; Humans ; Male ; Spinal Cord

OBJECTIVE: The incidence of leptomeningeal dissemination from malignant glioma is rare, so the clinical features of this are not well documented yet. We attempted to determine the clinical features of leptomeningeal dissemination from malignant gliomas. METHODS: We retrospectively analyzed 11 cases of leptomeningeal dissemination of malignant glioma, who were treated at our institution between 2006 and 2009. We investigated the clinical features of these patients by considering the following factors : tumor locations, the events of ventricular opening during surgery and the cerebrospinal fluid (CSF) profiles, including the cytology. RESULTS: The group was composed of 9 males and 2 females. The histological diagnosis of their initial intracranial tumors were 4 primary glioblastoma, 3 anaplastic astrocytoma, 1 anaplastic oligoastrocytoma, 2 ganglioglioma and 1 pleomorphic xanthoastrocyotma with anaplastic features. The mean age of the patients at the time of the initial presentation was 42.8+/-10.3 years. The mean time between surgery and the diagnosis of spinal dissemination was 12.3+/-7.9 (3-28) months. The mean overall survival after dissemination was 2.7+/-1.3 months. All our patients revealed a history of surgical opening of the ventricles. Elevated protein in the CSF was reported for eight patients who had their CSF profiles checked. CONCLUSION: We propose that in the malignant gliomas, the surgical opening of ventricles can cause the spinal leptomeningeal dissemination and the elevated protein content of CSF may be a candidate marker of leptomeningeal dissemination.
Astrocytoma ; Female ; Ganglioglioma ; Glioblastoma ; Glioma ; Humans ; Incidence ; Male ; Retrospective Studies

Desmoplastic infantile ganglioglioma is an uncommon variety of ganglioglioma that shows evidence of glial andganglionic differentiation accompanied by an extreme desmoplastic reaction. A 16-month-old girl was ad-mitted witha six-day history of left hemiparesis. MR imaging demonstrated a large multiseptated cystic mass, with a solidportion, in the white matter of the right frontotemporoparietal lobe. After contrast injections, the solid portionwas clearly enhanced. The presence of desmoplastic infantile ganglioglioma was confirmed by surgical resection. Wedescribe the characteristic radiologic and pathologic features of desmoplastic infantile ganglioglioma, andinclude a a review of the literature.
Female ; Ganglioglioma* ; Humans ; Infant ; Magnetic Resonance Imaging ; Paresis

Gangiogliomas are rare tumors, primarily seen in patients under the age of 30 years. They occure least commonly in the spinal cord. We present a 17-year-old girl who harbored an intramedullary conus ganglioglioma.
Adolescent ; Conus Snail* ; Female ; Ganglioglioma* ; Humans ; Spinal Cord

We present a case of ganglioglioma in the cerebellar vermis. A 2-year-old boy presented with symptoms and signs of raised intracranial pressure and the physical examination revealed large head and developmental delay. Magnetic resonance image demonstrated a hypointense mass in the cerebellar vermis on T1-weighted image with heterogeneous enhancement after gadolinium administration, mimicking a malignant tumor. A gross total resection was performed and pathologic findings demonstrated a ganglioglioma. There was no evidence of recurrence of the tumor during 16 months follow up period.
Cerebellum ; Child, Preschool ; Follow-Up Studies ; Gadolinium ; Ganglioglioma ; Head ; Humans ; Intracranial Pressure ; Male ; Physical Examination ; Recurrence

The incidence of sudden death due to undiagnosed primary intracranial tumor is very low in forensic autopsy practice. The ganglioglioma is a well differentiated, slow growing primary brain tumor that is encountered predominantly in childhood. We report a sudden, unexpected death in a 6-year-old girl from a ganglioglioma. On autopsy, there was an intraventricular tumor with recent hemorrhage, occupying the anterior aspect of the lateral ventricle and resulting in hydrocephalus. Acute intratumoral hemorrhage appears to be the mechanism of sudden death.
Autopsy ; Brain Neoplasms ; Child ; Death, Sudden ; Ganglioglioma ; Hemorrhage ; Humans ; Hydrocephalus ; Incidence ; Lateral Ventricles

Gangliogliomas are benign tumors, composed of neoplastic astrocytes and nerve cells. They are rare, account for 0.4-6.25% of all primary central nervous system neoplasms. Gangliogliomas affect predominantly infants or young adults. Gangliogliomas are preferentially encountered supratentorially, predominantly affecting the temporal lobe. Spinal gangliogliomas affect predominantly the cervical spinal cord. We report a case of cervical ganglioglioma which was successfully removed surgically, with a review of literature.
Astrocytes ; Central Nervous System Neoplasms ; Ganglioglioma* ; Humans ; Infant ; Neurons ; Spinal Cord ; Temporal Lobe ; Young Adult