Physiological and biochemical characteristics,drug sensitivity of pathogenic bacteria isolated from the diseased Sparus latus in Zhanjiang,Guangdong,and inactivated whole cell vaccine were studied.The results show that the isolated strain is Vibrio alginolyticus and is highly sensitive to tetracycline,gentamycin,chloramphenicol,and so on.But it is not sensitive to erythromycin and penicillin K.It also shows that the pathogen is inactivated more easily at pH6.0 than at pH8.4 when formalin is used.The whole cell vaccine can strengthen Sparus latus's immuno function and lessen their death rate when fish are infected by the Vibrio alginolyticus.

Body surface mapping is introduced in this paper. The research of bodysurface mapping involves two main aspects :data acquiring system and data processing methods. The recommended design applies the virtual instruments concept and high speed open bus standard. The data processing methods involve qualitative and quantitative methods. Dynamic and static mapping techniques are introduced as the qualitative methods. Statistical methods,inverse calculation and principle component analysis are introduced as the quantitative methods.

Objective To investigate the morphological difference of spinal single vertebral tuberculosis and metastasis by means of CT.Methods CT features of 16 cases of single vertebral tuberculosis and 17 cases of single vertebral metastasis which were proven by clinically and/or pathology, were retrospectively analyzed,and then the CT differential criteria of the two categories of diseases was recommended.Results The reliable CT findings for vertebral tuberculosis were as follows: involvement of anteriomedial potion of vatebral body,presence of sequstra in lesion ,marginal sclerosis in the edge of lesion,calcification within paravertebralmass or abscesses ,only edge enhancement of more of paravertebralmass.Metastasis was characterized by involvement of posteriomedial portion of vertebral bone,absence of sequestra within lesion ,no calcification within paravertebralmass.Both of them had normal intervertebral disc.Conclusion The different CT features of the single vertebral tuberculosis and metastasis are helpful in differerntiating diagnosis ,the morphological change of intervertebral discs is not helpful in differerntiating diagnosis .

Objective To observe the safety and efficacy of FOLFOX4 regiment in elderly versus young patients with advanced colorectal cancer. Methods There were 61 patients enrolled in this study, with 28 elderly patients aged 70 years and over, 33 young patients aged less than 70 years.They suffered from advanced/recurrent colorectal cancer and received FOLFOX4 regiment (Oxaliplatin +CF+5-FU). Every 14 days were as a cycle, and the therapeutic safety and efficacy were evaluated after three cycles. Adverse events and response to treatment were compared between the elderly and young patients. Results The main adverse effects were myelosuppression, gastrointestinal disturbance and neurotoxicity. The incidence rate of diarrhea was significantly higher in elderly patients than in young patients, but the most of diarrhea were at grade Ⅰ - Ⅱ. The incidence rates of leucocyte decrease and neutrophil decrease were higher in elderly patients than in young patients (92. 8% vs. 78. 8%, 39.3% vs. 36.3%), but there were no statistically significant differences between them. The incidence rate of neurotoxicity was 46.5% in elderly patients and 36.4% in young patients (P＞0. 05). The recent efficacy rate was 25%, disease control rate was 71.4% and median time-to-progression (TTP) was 6 months in elderly patients and 24.2%, 84.8% and 7 months in young patients (all P＞0.05). Conclusions FOLFOX4 regiment is well-tolerated and effective in both young and elderly patients.

Objective To evaluate the feasibility and safety of percutaneous transluminal angioplasty(PTA)using ? 30 mm balloon catheter to dilate the obstructive lesion of inferior vena cava(IVC)in Budd-Chiari syndrome(BCS). Methods From January 2002 to July 2006,146 consecutive patients with BCS(94 men,52 women)underwent color Doppler sonography including enhanced multislice CT(n = 47),and were confirmed by IVC angiography. All patients but 1 microsomia case were treated by PTA using ? 30 mm balloon catheter for dilation. IVC angiography were immediately performed to show patency of IVC and occurrence of any rupture or not after PTA. Follow-up color Doppler sonography was taken to evaluate the IVC patency and the PTA-related complication about 1 week after PTA. Results The mean transversial and longitudinal diameters of IVC at the junction level of right atrium and IVC were(25.09 ? 6.09) mm and(17.57 ? 3.93) mmrespectively in 46 cases with 3 D multi-slice CT preoperatively(1 case without measurement was due to the closest site with right atrium). There were no IVC rupture during the procedure. Conclusions Treatment of BCS by PTA using ? 30 mm big balloon catheter is feasible and safe.

Objective To investigate the relationship between pulse wave velocity and cardiovascular risk factors in prehypertensive subjects. Methods We selected 195 normotensives and divided them into two groups, which was 90 subjects with optimal blood pressure(BP

Objective To discuss the clinical value of intercostal arterial embolization for the treatment of hemoptysis.Methods A total of 91 patients with hemoptysis were enrolled in this study.Intercostal arterial embolization was performed using gelatin sponge.The patients were closely observed after the operation.For recurrent cases,re-embolization was carried out after identifying the causes of relapse.Results A total of 111 operations were performed on the 91 patients,including embolization of the bronchial and intercostal arteries in 74 cases,and simple embolization of the intercostal artery in 17.The rate of immediate hemostasis was 98.9%(90/91).The patients were followed up for 8 to 14 months,during which the recurrent rate was 15.4%(14/91).No serious complication occurred during the follow-up.Conclusion By embolizing both bronchial and intercostal arteries,the efficacy of the procedure can be increased and the rate the recurrence decreased,as long as proper measures have been taken to avoid serious complications.

Beginning with the authors' experience in analytic-chemistry bilingual teaching,this article probes into some problems of analytic-chemistry in undergraduate education.And the authors give some beneficial suggestions in the teaching material construction,teachers training and teaching quality control.

The present situation and problems in experiment teaching of analytical chemistry were explained,and innovation was explored and practiced in the faculty of laboratory medicine,including the opitimization of teaching contents,teaching methods and score system evaluation reformation.