Acute kidney injury ( AKI) in newborns is one of neonatal critical disease,the incidence of AKI is 23%and the mortality is 25%~50%in neonatal intensive care unit (NICU).AKI in newborns is ab-normal renal function due to many various unfavorable factors,such as neonatal asphyxia,low blood volume, shock,hypoxia,hemolysis,low temperature,the clinical manifestations are oliguria or anuria,electrolyte disturb-ance,acid-base imbalance, high concentrations of metabolites in plasma and renal excretion ( urea, creatinine etc.) .At present,there are no effective prevention measures.In recent years,with the progress of blood purifica-tion technology,continuous blood purification ( CBP) has been used from AKI in children to AKI in newborns. Because of the neonatal hemodynamic instability and blood characteristics of small capacity, the application of CBP in the neonatal AKI still faces many problems.The paper summarizes high risk factors and diagnostic crite-ria of AKI in newborns,related problems of neonatal CBP treatment.

Objective To observe the clinical efficacy of intradermal needle therapy in treating chronic pharyngitis.Method Sixty patients with chronic pharyngitis were randomized into a treatment group and a control group, 30 cases in each group. The treatment group was intervened by intradermal needle therapy at Lieque (LU 7) and Zhaohai (KI 6), while the control group was by Compound Borax solution plus Cydiodine Buccal tablets. The symptoms were scored before and after treatment, and the clinical efficacies were compared.Result The total effective rate was 93.3% in the treatment group versus 80.0% in the control group, and the difference was statistically significant (P<0.05). The symptom scores were markedly changed after the treatment in both groups (P<0.01). The symptom score of the treatment group was significantly different from that of the control group (P<0.05). Conclusion Intradermal needle therapy is an effective method in treating chronic pharyngitis.

Rectal cancer is a common malignant tumor in the gastrointestinal system.For the patients with resectable but high-risk rectal cancer,neoadjuvant and adjuvant chemoradiation plus surgery may improve local control.Compared to adjuvant chemoradiation,neoadjuvant chemoradiation showed the advantage of sphincter preservation.When the goal of preoperative chemoradiation was sphincter preservation,conventional radiotherapy was recommended.Through the analysis of the patients with 5-year survivals,the radiation had a similar impact on the survival as the chemotherapy alone for the patients with the intermediate risk factors.The impact on local control need to be further investigated before recommending chemotherapy alone for those subset patients.Advances in preoperative irradiation,postoperative irradiation and the comparison of preoperative irradiation with postoperative irradiation are also reviewed in this article.

[Objective]To study the effect of tibial diaphyseal lengthening on the longitudinal growth of the tibia.[Method]Rabbit models of tibial diaphyseal lengthening and tibial osteotomy were established.Standard radiography of the tibia was taken and the length of the tibia was measured.Histology of the proximal and distal tibia was made and the thickness of the growth plate was measured.[Result]Tibial osteotomy alone stimulated the longitudinal growth of the tibia and increased the thickness of the growth plate.However,tibial diaphyseal lengthening suppressed this stimulation resulting in natural longitudinal growth and normal thickness of the growth plate that matched the normal side.[Conclusion]Diaphyseal lengthening of tibia does not inhibit the longitudinal growth of the tibia.

Objective To study the effect of CO 2 pneumoperitoneum and enteric disturbance on serum ?-endorphin (?-EP) in SD rats, in order to investigate their influence on peri-operative stress responses in SD rats. Methods A total of 120 SPF-grade male SD rats were randomly divided into four groups with 30 rats in each group. The four groups received CO 2 pneumoperitoneum (Group A), a 5 cm abdominal incision (Group B), a 5 cm abdominal incision with gastroenteric disturbance (Group C), and intraperitoneal anesthesia (Group D or Control Group), respectively. Concentrations of serum ?-EP of these groups were measured 10 min, 20 min, and 40 min after the beginning of surgery, respectively. Results Concentrations of serum ?-EP in the Group A 10 min, 20 min, and 40 min after the beginning of surgery were 274 7?66 6 pg/dl, 157 3?63 8 pg/dl, and 163 9?74 5 pg/dl, respectively, which were all extremely significantly higher than those in the Control Group ( P

Computer-Aided Design ; Humans ; Mandibular Fractures ; diagnostic imaging ; surgery ; Mandibular Neoplasms ; diagnostic imaging ; surgery ; Mandibular Reconstruction ; methods ; Surgery, Computer-Assisted ; methods ; Tomography, X-Ray Computed

Face ; surgery ; Humans ; Mouth ; surgery ; Reconstructive Surgical Procedures ; Retrospective Studies

Facial Nerve Injuries ; rehabilitation ; surgery ; Humans

Objective To study clinical and histopathological features of high-risk small renal carcinoma and provide theoretical basis for the individualized treatment.Methods This retrospective study analyzed the clinical and histological data of 21 patients of high-risk small renal cell carcinomas which were highly aggressive or advanced stage, admitted from Jan 2000 to July 2015.There were 15 males and 6 females,and the average age was (61.5 ±7.1) years (ranged 27 to 75 years).The mean diameter of tumors was 3.3cm (ranged 2.0 to 4cm).The study mainly focused on pathological character and stage, Fuhrman grading, existence of perirenal tissue or vascular invasion, venous embolus and distant metastasis.Results Of all these 21 cases, 17 cases were clear cell carcinomas, 1 was papillary carcinoma, 2 were hybrid cellular tumor ( malignant rhabdoid tumor and sarcomatoid carcinoma) and 1 was sarcomatoid carcinoma. Among the 17 clear cell carcinoma cases, 12 were Fuhrman grade Ⅱ, 5 were grade Ⅲ and one was gradeⅣ.Tumor infiltrated renal vein or its branches and renal vein embolus were found in 7 cases.The tumor infiltrated perirenal or renal sinus fat were found in 11 cases.Synchronous lung and local lymph nodes metastasis were found in 3 patients respectively.Moreover, there was 1 case with metastasis to the brain (FuhrmanⅣ).The final clinical stage were T3a N0M0 in 14,T1a N1M0 in 3 and T1a N0M1 in 4 cases. Conclusions Small renal tumors are heterogeneous in its biological behavior and the minorities are aggressive with infringement of perirenal fat or simultaneous local lymph node or distant metastasis.When the tumor is greater than 3.0 cm in diameter and with high grade in Fuhrman classification, sarcomatoid carcinoma are more likely to be highly aggressive and advanced stage.

[Objective]To measure the in vivo knee joint reaction force in a rabbit model of tibial diaphyseal lengthening.[Method]Sixteen immature (8 weeks old) New Zealand White rabbits were underwent 30% (left) tibial diaphyseal lengthening at a rate of two 0.4 mm incremental lengthenings per day.The knee joint reaction force was measured at the end of lengthening (8 rabbits,13 weeks old) and 5 weeks later (8 rabbits,18 weeks old).An instrumented bilateral distractor and an extensometer were fixed cross the knee joint.The joint distraction force and distraction displacement were measured immediately after each incremental distraction of the joint.[Result]The joint reaction force on the lengthened side was significantly higher than that of the control side at both time points (44.4?7.8 N v.27.2?4.0 N at 13 weeks of age,44.3?6.5 N v.31.3?3.0 N at 18 weeks of age).[Conclusion]The knee joint reactive force could be increased in 30% tibial disphyseal lengthening which potentially could lead to the risk of damage to artic ular cartilage.