The latest results from the FLEX trial wag presented in ASCO annual meeting which was hold in June.2008 in Chicago.The study demonstrated that chemotherapy based on Cetuximab plus Cisplatin significantly increased the overall survival of NSCLC patients,including all histological subtypes.The new findings confirm that Erbitux is the first targeted thempy to show a significant survival benefit in NSCLC patients across all histological subtypes.

Humans ; Male ; Middle Aged ; Neoplasms, Radiation-Induced ; etiology ; Occupational Diseases ; etiology

Objective To investigate the complication and its treatment method of the percutaneous nephrolithotomy(PCNL).Methods The clinical data of 137 patients with PCNL,were retrospectively analyzed statistical analysis of complications.Results In 137 cases of PCNL,83 cases were male,54 cases were female; 103 cases of kidney stones,ureteral calculi in 34 cases,including 24 cases of ureteral calculi with renal calculi.All patients were cured,no patients died;complications occurred in 9 cases,in which the puncture failure in 1 case,renal hemorrhage in 5 cases,postoperative arteriovenous fistula in 1 case,infection in 2 cases.Conclusion PCNL is minimally invasive,effective,but still had more serious complications.We should strengthen the prevention and cure measures.

Alpha-fetoprotein (AFP) was first discovered over 50 years ago, and is currently applied clinically in diagnosis, effects evaluation and relapse judgement of tumors especially for the primary hepatocellular carcinomas.And as an effective tumor marker, AFP test has become one of the essential items in physical examination.However, its clinical application is not limited to primary hepatocellular carcinomas,and its great application value has been proved in many benign diseases and other tumors (non-hepatic carcinomas).

The incidence of gastroesophageal junction cancers is rapidly increasing, the Year' s upwards rate being more than 5％ ～ 10％. Siewert in 1987 proposed a definition for adenocarcinoma of the esophagogastric junction (AEG), as a adenocarcinoma within 5 cm of the gastroesophageal junction (GEJ), and divided AEG in to three types. The majority of patients with AEG in Asian countries have type Ⅱ and Ⅲ cancers, and no obvious differences have been reported in 5-year survival rates between patients with different types of AEG. In contrast, in western countries, the distribution of each type of AEG is nearly equal,patients with AEG type Ⅰ cancer have the best prognosis, whereas the overall survival of patients with type Ⅲ cancer is the worst. Now people presume that the AEG is a special type of carcinoma which is not same as carcinoma of esophagus and stomach. The surgical routes and operative methods and the extent of lymph node dissection of AEG are still not completely clear, and AEG lacks also a independent TNM system for itself. We will summarize the actuality of diagnosis and therapy of AEG.

Objective To summarize the endoscopic characteristics of Primary Gastrointestinal Malignant Lymphoma (PGIML) and increase the diagnostic accuracy of this method to aid the clinical treatment.Methods The clinical data of 67cases with PGIML from 2004 to 2009 were studied retrospectively.ResultsPGIML lacked specific clinical symptoms.The main clinical symptoms were abdominal pain, melena and abdominal mass.In our study, most PGIML(37/67,55.8％)were detected in stomach.Nodular appearance of mucosal surface was the most common endoscopic finding.The positive rate of endoscopic biopsy for the diagnosis of PGIML was 68.7 ％ (46/67 biopsy cases).All cases had Non-Hogkin Lymphoma (NHL).The most common immunophenotype was B-cell majority (50/67).Thirty cases had MALT.ConclusionIt is hard to diagnose PGIML at early stage,combination of various diagnosis tests should be considered to solve this problem.The effectiveness of surgery on PGIML should be further confirmed by prospective randomized clinical trials.

Objective To explore the possibility of finding pulmonary embolish by CT scan. Methods 20 cases of patients with pulmonary embolism comfirmed by CTA were selected. The CT scan was compared with the enhance film in the same level of contrast observation site. Results 12 cases found in plain site with the CTA form show abnormal density within the same lumen shadow. Indirect signs of bronchial artery dilatation except plain and outside the CTA showed no difference. Conclusion Pulmonary embolism in the carefully observed before enhanced large artery can be found within the thrombus.

Animals ; Disease Models, Animal ; Drugs, Chinese Herbal ; pharmacology ; therapeutic use ; Female ; Heat Stress Disorders ; drug therapy ; metabolism ; Hypothalamus ; metabolism ; Male ; Neurotensin ; metabolism ; Phytotherapy ; Rats ; Rats, Wistar ; Tablets

Acupuncture Points ; Adolescent ; Adult ; Bloodletting ; Female ; Humans ; Male ; Middle Aged ; Psoriasis ; therapy ; Young Adult

Objective To explore the effect of treating circumferential mixed hemorrhoids with surgery and Chinese herbal medicine "Hemorrhoids Ⅱ sitz bath fluid".Methods Eighty-one patients with circumferential mixed hemorrhoids were treated by surgical resection firstly.After operation,"Hemorrhoids Ⅱ sitz bath fluid" was given to each patient and the clinic effects were analyzed after treatment.Results All 81 patients were cured for one treatment,and one-year's recurrence rate was 1.2%.Conclusion The effects of surgery combined with Chinese herbal medicine "Hemorrhoids Ⅱ sitz bath fluid"is excellent in the treatment of circumferential mixed hemorrhoids.