Gallbladder (GB) cancer occurs predominately as a biliary tract malignant tumor. It generally has a very poor prognosis, and early detection is often difficult. A variety of carcinogens have been implicated as an important cause for GB cancer. Benzene is a well-known carcinogen for hematologic malignancy, and its casual relationship with GB cancer has been suggested. We report a case of two patients who had operated a laundry cleaning facility together and later simultaneously got GB cancer after prolonged benzene exposure.
Adenocarcinoma/*diagnosis/etiology/ultrasonography ; Benzene/*toxicity ; Female ; Gallbladder Neoplasms/*diagnosis/etiology/ultrasonography ; Humans ; Laundering ; Male ; Middle Aged ; Positron-Emission Tomography and Computed Tomography ; Tomography, X-Ray Computed

Radiofrequency ablation (RFA) is performed as an alternative to surgical resection for primary or secondary liver malignancies. Although RFA can be performed safely in most patients, early and late complications related to mechanical or thermal damage occur in 8-9.5% cases. Hemocholecyst, which refers to hemorrhage of the gallbladder, has been reported with primary gallbladder disease or as a secondary event associated with hemobilia. Hemobilia, defined as hemorrhage in the biliary tract and most commonly associated with accidental or iatrogenic trauma, is a rare complication of RFA. Here we report a case of hemocholecyst associated with hemobilia after RFA for hepatocellular carcinoma that was successfully managed by laparoscopic cholecystectomy.
Aged ; Carcinoma, Hepatocellular/*surgery ; Catheter Ablation/*adverse effects ; Cholangiopancreatography, Endoscopic Retrograde ; Cholecystectomy ; Gallbladder Diseases/*etiology/surgery/ultrasonography ; Hemobilia/diagnosis/*etiology/surgery ; Hemorrhage/*etiology ; Humans ; Liver Neoplasms/*surgery ; Male ; Tomography, X-Ray Computed