1.A Case of Hemorrhagic Gallbladder Paraganglioma Causing Acute Cholecystitis.
Young Up CHO ; Jang Yong KIM ; Sun Keun CHOI ; Yoon Seok HUR ; Keon Young LEE ; Sei Joong KIM ; Seung Ik AHN ; Kee Chun HONG ; Ze Hong WOO ; Jee Young HAN ; Seok Hwan SHIN
Yonsei Medical Journal 2001;42(3):352-356
Gallbladder paraganglioma is a very rare tumor and so far only a few cases have been reported. Most of these were asymptomatic and were found incidentally during operation. Recently, we experienced a gallbladder paraganglioma that gave rise to hemorrhage, which in turn caused acute cholecystitis. Our case involved a 45 year-old female patient complaining of an intermittent right upper abdominal pain. After a preoperative evaluation, cholecystectomy and lymphadenectomy were performed under the impression of gallbladder cancer with acute cholecystitis. Postoperative pathologic examination revealed a hemorrhagic gallbladder paraganglioma accompanied by acute cholecystitis. Immunohistochemical staining of the chief cells for neuron specific enolase, chromogranin and synaptophysin were positive. Sustentacular cells also stained positively for S100 protein.
Acute Disease
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Case Report
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Cholecystitis/*etiology
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Female
;
Gallbladder Neoplasms/*complications/pathology
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Hemorrhage/*complications
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Human
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Immunohistochemistry
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Middle Age
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Paraganglioma/*complications/pathology
2.An Experience of Cyberknife Treatment in Patients with Advanced Pancreaticobilliary Malignancy.
Yun Ho JUNG ; Hyun Sook CHOI ; Young Koog CHEON ; Jong Ho MOON ; Young Deok CHO ; Ah Ram CHANG ; Jong Ho WON
The Korean Journal of Gastroenterology 2011;58(5):264-269
BACKGROUND/AIMS: CyberKnife(TM) stereotactic body radiotherapy (SBRT) has been thought as a promising treatment modality for inoperable or recurred pancreaticobiliary malignancies. But, clinical course of CyberKnife(TM) treatment have not been established yet, so we report the experience of CyberKnife(TM) treatment in 19 patients with recurred or advanced pancreaticobilliary malignancies. METHODS: Between July 2008 and May 2009, 19 patients (gallbladder cancer 4, common bile duct cancer 5, and pancreatic cancer 10) with recurred (12) and advanced pancreaticobiliary cancer (7) underwent CyberKnife(TM) treatment in Soonchunhyang University Hospital. Tumor size was evaluated at 1, 3, 6, 8 and every 3 months after SBRT. RESULTS: The mean age was 60.2 years, and the mean size of target lesions was 28.1+/-1.30 mm. After CyberKnife(TM) treatment, the average size of target lesions was decreased; 2.53+/-4.18 mm from months 0-1 in 19 patients, 2.47+/-4.7 mm from months 1-3 in 15 patients, 0.08+/-5.11 mm from months 3-6 in 12 patients. However, the average size of target lesions was increased 3.67+/-8.98 mm from months 6-8 in 6 patients. There were 2 cases of massive duodenal ulcer bleeding after CyberKnife(TM) treatment, one of them expired due to ulcer bleeding. Also, other minor complications appeared such as 1 case of abdominal pain and 1 case of diarrhea. CONCLUSIONS: CyberKnife(TM) treatment seems to be effective in local control of pancreaticobiliary cancer, but we experienced serious complications. Further prospective studies will be needed for the proper evaluation of role of Cyberknife(TM) treatment in patients with advanced pancreaticobiliary malignancies.
Adult
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Aged
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CA-19-9 Antigen/analysis
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Common Bile Duct Neoplasms/complications/pathology/*surgery
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Female
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Gallbladder Neoplasms/complications/pathology/*surgery
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Gastrointestinal Hemorrhage/etiology
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Humans
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Male
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Middle Aged
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Pancreatic Neoplasms/complications/pathology/*surgery
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Radiosurgery
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Retrospective Studies
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Tomography, X-Ray Computed
3.RE: Metastasis of Gallbladder Adenocarcinoma to Bauhin's Valve: An Extremely Rare Cause of Intestinal Obstruction.
Edoardo VIRGILIO ; Valentina GIACCAGLIA ; Genoveffa BALDUCCI
Korean Journal of Radiology 2014;15(5):655-656
No abstract available.
Adenocarcinoma/*complications/*diagnosis/pathology
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Aged, 80 and over
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Colonoscopy
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Ethanol/therapeutic use
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Female
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Gallbladder Neoplasms/*complications/*diagnosis/pathology
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Humans
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Intestinal Obstruction/*etiology
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Liver Neoplasms/complications/drug therapy/secondary
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Tomography, X-Ray Computed
4.Simultaneous Xanthogranulomatous Cholecystitis and Gallbladder Cancer in a Patient with a Large Abdominal Aortic Aneurysm.
Yahya AL-ABED ; Mohammed ELSHERIF ; John FIRTH ; Rudi BORGSTEIN ; Fiona MYINT
The Korean Journal of Internal Medicine 2012;27(3):338-341
There have been reports of the coexistence of abdominal aortic aneurysm (AAA) with intra-abdominal malignancy including gastric, colonic, pancreatic, and renal. We herein report a case of a previously undiagnosed AAA and a presenting complaint consistent with acute cholecystitis. Following cholecystectomy, this was noted to be a rare form of chronic cholecystitis: xanthogranulomatous cholecystitis. There is a known possible association of this uncommon condition with gallbladder cancer. The management of concomitant pathologies can present a real challenge to the multidisciplinary team, especially with large aneurysms.
Adenocarcinoma/*complications/radiography/secondary/surgery
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Aged
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Aortic Aneurysm, Abdominal/*complications/radiography/surgery
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Biopsy
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Blood Vessel Prosthesis Implantation
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Cholecystectomy
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Cholecystitis/*complications/pathology/radiography/surgery
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Endovascular Procedures
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Female
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Gallbladder Neoplasms/*complications/pathology/radiography/surgery
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Granuloma/*complications/pathology/radiography/surgery
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Humans
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Tomography, X-Ray Computed
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Treatment Outcome
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Xanthomatosis/*complications/pathology/radiography/surgery
5.A Case of Simultaneous Xanthogranulomatous Cholecystitis and Carcinoma of the Gallbladder.
Hyo Sup LEE ; Kwang Ro JOO ; Do Ha KIM ; Neung Hwa PARK ; Yoong Ki JEONG ; Jae Hee SUH ; Chang Woo NAM
The Korean Journal of Internal Medicine 2003;18(1):53-56
Xanthogranulomatous cholecystitis (XGC) is a rare inflammatory disease of the gallbladder. Not only does XGC occasionally present as a mass formation with adjacent organ invasion like a malignant neoplasm, it can also infrequently be associated with gallbladder cancer. In the situation, it is difficult to make a differential diagnosis between the diseases. Here, we describe a case of a simultaneous XGC and a carcinoma of the gallbladder in a 61-year-old woman. To the best of our knowledge, there are only a small number of reports on this combination of diseases.
Adenocarcinoma/complications/diagnosis/*pathology/surgery
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Biopsy, Needle
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Cholangiopancreatography, Endoscopic Retrograde
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Cholecystitis/complications/diagnosis/*pathology/surgery
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Endosonography
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Female
;
Gallbladder Neoplasms/complications/diagnosis/*pathology/surgery
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Granuloma/complications/diagnosis/*pathology
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Humans
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Immunohistochemistry
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Middle Aged
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Neoplasm Staging
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Prognosis
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Risk Assessment
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Tomography, X-Ray Computed
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Xanthomatosis/complications/diagnosis/*pathology
6.Histopathologic Analysis of Adenoma and Adenoma-related Lesions of the Gallbladder.
Seung Ho LEE ; Dal Sik LEE ; Il Young YOU ; Won Joong JEON ; Seon Mee PARK ; Sei Jin YOUN ; Jae Woon CHOI ; Rohyun SUNG
The Korean Journal of Gastroenterology 2010;55(2):119-126
BACKGROUND/AIMS: In order to determine the malignant potential of gallbladder adenoma for progression to carcinoma, we evaluated the histopathologic features of adenoma and adenoma-related lesions on cholecystectomized specimens. METHODS: Among 1,847 cholecystectomized specimens, 63 specimens from 26 benign adenomas, 9 carcinomas in situ (CIS), and 28 invasive carcinomas were selected. A pathologist reviewed all specimens and selected benign adenomas, CIS in the adenoma, and adenoma residue in invasive carcinomas. Adenomas and adenoma-related lesions were classified according to morphology (tubular, tubulopapillary, and papillary) and the consisting epithelium (biliary, pyloric metaplasia, and intestinal metaplasia). The age and the size of the benign adenomas and carcinomas in the adenoma were also compared. RESULTS: Adenoma and adenoma-related lesions were found in 34 out (1.8%) of all resected gallbladder. Among 9 CIS and 28 invasive carcinomas, adenoma-related lesions were detected in 7 and 1 case, respectively. All eight carcinomas arising in the adenoma were well-differentiated solitary tumors. The diameters of the carcinomas in the adenoma were, on average, larger than that of the benign adenomas (1.8 cm vs. 0.9 cm, p=0.01). The patients with carcinomas in the adenoma were, on average, older than those with benign adenomas, although the difference was insignificant (57 years vs. 47 years, p=0.09). The morphology and consisting epithelium did not differ between the benign adenomas and carcinomas in the adenoma. The malignant transformation occurred in 23.5% of adenomas. CONCLUSIONS: Gallbladder adenoma is a rare disease, although malignant transformation occurs frequently. Adenoma is a precancerous lesion and the adenoma-carcinoma sequence is one of the gallbladder cancer carcinogenesis.
Adenoma/epidemiology/*pathology/surgery
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Adult
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Age Factors
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Aged
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Carcinoma/epidemiology/pathology/surgery
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Cell Transformation, Neoplastic
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Cholecystectomy
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Cystadenoma/epidemiology/pathology/surgery
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Female
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Gallbladder Neoplasms/epidemiology/*pathology/surgery
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Gallstones/complications
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Humans
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Male
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Middle Aged
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Neoplasm Invasiveness