1.Grounded Theoretical Analysis on the Hospital Accreditation Experience of Head Nurses in General Hospitals.
Ji Hyun MOON ; Ga Eul JOO ; Jinhwa LEE
Journal of Korean Academy of Nursing Administration 2016;22(5):437-447
PURPOSE: The purpose of this study was to conduct a grounded theoretical analysis on the hospital accreditation experience of head nurses in order to understand their behavior on the adaption of this new system. METHODS: The participants were 8 head nurses with more than 3 years of experience. The data were collected through in-depth interviews using audiotape recording analyzed by the constant comparative method described in Strauss and Corbin's methodology. RESULTS: There were 113 concepts, 26 subcategories and 12 categories identified through the open coding process. In the axial coding, the following paradigm model was proposed: 1) the causal conditions were ‘hardware problem’ and ‘software problem’, 2) the contextual conditions were ‘vertical relationship’, ‘individual preference’, and ‘family support’, 3) the intervening conditions were ‘passive conditions’ and ‘active conditions’, 4) the action/interaction strategies were ‘leading role’ and ‘dependent role’, 5) the consequences were ‘positive acceptance’ and ‘negative acceptance’, 6) the central phenomenon was ‘difficult situation’ and 7) the core category was ‘leading in harmony’. CONCLUSION: The new system led head nurses having difficulties as the middleman between the hospital administration and general nurses, but they made a continuous effort to overcome and adapt to it through a number of strategies.
Accreditation*
;
Clinical Coding
;
Grounded Theory
;
Head*
;
Hospital Administration
;
Hospitals, General*
;
Methods
;
Nursing, Supervisory*
;
Tape Recording
2.Effects of a Standardized Patient Simulation Program for Nursing Students on Nursing Competence, Communication Skill, Self-efficacy and Critical Thinking Ability for Blood Transfusion.
Ga Eul JOO ; Kyeong Yae SOHNG ; Hee Ju KIM
Journal of Korean Academy of Fundamental Nursing 2015;22(1):49-58
PURPOSE: This study was conducted to identify the effects of a standardized patients (SP) simulation program for nursing students on nursing competence, communication skill, self-efficacy and critical thinking ability for blood transfusion. METHODS: A nonequivalent control group non-synchronized design study was used and included as participants 96 junior nursing students at C University. The SP group (n=48) participated in the teaching class using a SP, while the control group (n=48) received conventional practice education. The outcome measurements were nursing competence, communication skill, self-efficacy, and critical thinking ability for transfusion. RESULTS: Nursing competence, communication skill, self-efficacy, and critical thinking ability improved for students in both groups after training (2.01< or =t< or =13.03, p<.05). Self-efficacy showed greater improvement in students in the SP group compared to the control group (t=3.36, p<.001). CONCLUSION: SP simulation practice may be more effective in enhancing self-efficacy than that of conventional practice education. Whether self-efficacy will contribute to enhancing learning motivation for nursing students needs further examination.
Blood Transfusion*
;
Clinical Competence
;
Education
;
Humans
;
Learning
;
Mental Competency*
;
Motivation
;
Nursing*
;
Patient Simulation*
;
Self Efficacy
;
Students, Nursing*
;
Thinking*
3.The Development and Evaluation of a New Educational Program, Introduction to Clinical Nursing, for Third Year Nursing Students.
Kyungae SONG ; Hyun Jung PARK ; Hye A YEOM ; Jong Eun LEE ; Ga Eul JOO ; Hee Ju KIM
Journal of Korean Academy of Fundamental Nursing 2012;19(3):322-333
PURPOSE: The purpose of this study was to evaluate the effects of a newly developed Introduction to Clinical Nursing (ICN) program on critical thinking skills, communication competence, self-efficacy, and clinical performance self-confidence in nursing students in their third year. METHODS: One group pre-test and post-test design was used with three data collection time points (pre-test, post-test1 and post-test2). Participants were 74 third year nursing students approaching their first clinical practicum. The new program included (a) simulated clinical encounters regarding situations of assessing hospitalized patents and caring for patients with oxygenation needs, (b) objective structured clinical examination of skills, (c) lectures, and (e) field trips. Data were analyzed using paired t-tests. RESULTS: After the ICN course, critical thinking skills(significant only between pretest and post-test2), communication competence, and clinical performance self-confidence improved significantly (p<.05). There was no improvement in the self-efficacy total score but there was significant improvement in the subscale, self-regulatory efficacy. CONCLUSIONS: The study results indicate that the ICN course may be effective in increasing critical thinking skills, communication competence, and clinical performance self-confidence in nursing students. However, the effect size was very small and modifications of this program should be considered to develop more cost-effective educational programs.
Surveys and Questionnaires
;
Humans
;
Lectures
;
Mental Competency
;
Oxygen
;
Students, Nursing
;
Thinking
4.Geriatric functional assessment for decision-making on adjuvant chemotherapy in older colon cancer patients
Hyun Jin BANG ; Hyun Jeong SHIM ; Ga Ram KIM ; Jun Eul HWANG ; Woo Kyun BAE ; Ik Joo CHUNG ; Sang Hee CHO
The Korean Journal of Internal Medicine 2022;37(3):660-672
Background/Aims:
Despite the increasing need for geriatric assessment prior to chemotherapy, the method for this assessment remains inadequate for older cancer patients. We aimed to propose a simple assessment method to predict the performance of adjuvant chemotherapy in older patients after colon cancer surgery.
Methods:
This prospective study included patients over 65 years of age who were scheduled for adjuvant chemotherapy after colon cancer surgery. Before initiating chemotherapy, their functional status was assessed on the basis of activities of daily living (ADL)/instrumental activities of daily living (IADL). These parameters were analyzed with clinical characteristics and the patterns of adjuvant chemotherapy. The focus was on the completion rate of adjuvant chemotherapy.
Results:
A total of 89 patients with a median age of 72 years were analyzed. Among them, 54 (61%) were non-impaired and 35 (39%) were impaired regarding their ADL/IADL classification. Low body mass index and impairment of ADL/IADLs were significantly associated with chemotherapy interruption. Among toxicities, fatigue and hand-foot syndrome were independent prognostic factors for chemotherapy interruption. Impairments of ADL/IADL were significantly associated with fatigue regardless of age. Based on age and ADL/IADL stratification, younger patients (≤ 72 years) and/or those who were ADL/IADL non-impaired were significantly more likely to complete adjuvant chemotherapy than older patients (> 72 years) and ADL/IADL impaired patients (p = 0.038). This was regardless of the chemotherapy regimen.
Conclusions
Functional assessment using ADL/IADL is a convenient method to predict chemotherapy toxicity and performance. These results suggested that routine screening for ADL/IADLs could guide appropriate patient selection for the completion of adjuvant chemotherapy and predict expected outcomes.
5.In silico Screening of Chemical Libraries to Develop Inhibitors That Hamper the Interaction of PCSK9 with the LDL Receptor.
Dong Kook MIN ; Hyun Sook LEE ; Narae LEE ; Chan Joo LEE ; Hyun Joo SONG ; Ga Eul YANG ; Dojun YOON ; Sahng Wook PARK
Yonsei Medical Journal 2015;56(5):1251-1257
PURPOSE: Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to the low density lipoprotein receptor (LDLR) and promotes degradation of the LDLR. Inhibition of PCSK9 either by reducing its expression or by blocking its activity results in the upregulation of the LDLR and subsequently lowers the plasma concentration of LDL-cholesterol. As a modality to inhibit PCSK9 action, we searched the chemical library for small molecules that block the binding of PCSK9 to the LDLR. MATERIALS AND METHODS: We selected 100 chemicals that bind to PCSK9 where the EGF-AB fragment of the LDLR binds via in silico screening of the ChemBridge chemical library, using the computational GOLD algorithm analysis. Effects of chemicals were evaluated using the PCSK9-LDLR binding assay, immunoblot analysis, and the LDL-cholesterol uptake assay in vitro, as well as the fast performance liquid chromatography assay for plasma lipoproteins in vivo. RESULTS: A set of chemicals were found that decreased the binding of PCSK9 to the EGF-AB fragment of the LDLR in a dose-dependent manner. They also increased the amount of the LDLR significantly and subsequently increased the uptake of fluorescence-labeled LDL in HepG2 cells. Additionally, one particular molecule lowered the plasma concentration of total cholesterol and LDL-cholesterol significantly in wild-type mice, while such an effect was not observed in Pcsk9 knockout mice. CONCLUSION: Our findings strongly suggest that in silico screening of small molecules that inhibit the protein-protein interaction between PCSK9 and the LDLR is a potential modality for developing hypercholesterolemia therapeutics.
Animals
;
Cholesterol/*blood
;
Cholesterol, LDL/blood
;
Hep G2 Cells
;
Humans
;
Mice
;
Mice, Knockout
;
Proprotein Convertases/*metabolism
;
Receptors, LDL/*metabolism
;
Serine Endopeptidases/*metabolism
;
*Small Molecule Libraries
6.Graft Functions and Survivals according to the Serum Creatinine Level at 3 Days after Renal Transplantation in Living-donor Renal Transplantation.
Bum Soon CHOI ; Ga Eul JOO ; Jin Dong KIM ; Seung Hawn LEE ; Jae Wook KIM ; Suk Joon SHIN ; Chul Woo YANG ; Yong Soo KIM ; In Sung MOON ; Yong Bok KOH ; Byung Kee BANG
The Journal of the Korean Society for Transplantation 2003;17(2):144-149
PURPOSE: The aim of this study was to evaluate whether serum creatinine levels at 3 days after renal transplantation can predict long-term graft survival and its associated clinical aspects. METHODS: Three hundred and seventy six renal transplant recipients who received grafts from living donors were included. Recipients were classified into two groups according to their serum creatinine levels (
Biopsy
;
Body Weight
;
Creatinine*
;
Dialysis
;
Female
;
Graft Survival
;
Humans
;
Kidney
;
Kidney Transplantation*
;
Living Donors
;
Transplantation
;
Transplants*
7.Comparison of the Effects of Middle Ear Implants and Conventional Hearing Aids on Cognitive Function.
Choon Dong KIM ; Hyun Sang CHO ; Young Soon YANG ; Hun Hee BAEK ; Sung Hwan LIM ; Hye Mi PARK ; Ga Eul CHOI ; Eun Joo CHOI ; Shin Ae KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 2017;60(12):633-639
BACKGROUND AND OBJECTIVES: The association between hearing impairment and cognitive function has been established in previous studies. The aim of this study was to compare the effects of conventional hearing aids and middle ear implants on cognitive function. SUBJECTS AND METHOD: This study included 22 participants who underwent middle ear implantation between October 2013 and September 2016. Their mean age at surgery was 70 years. Using Pure tone audiometry (PTA), the Speech discrimination test (SDT), and the Abbreviated Profile of Hearing Aid Benefit (APHAB) questionnaire, we compared audiologic benefits of three conditions [without hearing aids, with conventional hearing aids, or with Vibrant Sound bridge (VSB)]. Cognitive ability was evaluated using neuropsychological testings (Seoul Neuropsychological Screening Battery) at intervals of approximately eight weeks. RESULTS: The results of PTA showed a 7.96 dB HL gain with conventional hearing aids and a 10.00 dB HL gain with the use of VSB. SDT results showed a 4.10% gain with conventional hearing aids and a 10% gain with the use of VSB. Results of the APHAB questionnaire showed a significant increase with the use of VSB compared to conventional hearing aids. In the Korean Mini-Mental State Examination, a slight improvement was observed after middle ear implantation. In the Digit Span Test and Korean-Boston Naming Test, a significant improvement was seen with the use of VSB compared to conventional hearing aids. CONCLUSION: The use of middle ear implants in rehabilitation of hearing communication in patients showed improvements in cognitive abilities, compared to the use of conventional hearing aids.
Audiometry
;
Cognition*
;
Ear, Middle*
;
Hearing Aids*
;
Hearing Loss
;
Hearing*
;
Humans
;
Mass Screening
;
Methods
;
Neuropsychological Tests
;
Ossicular Prosthesis*
;
Rehabilitation
;
Speech Discrimination Tests