1.Ultrasonic Diagnosis and Aspiration of Spontaneous Renal Subcapsular Hematoma
Chinese Journal of Ultrasonography 1995;4(2):78-80
This paper described 8 patients in whom a spontaneeus renal subeapsular hematoma devel-oped.Two cases with systemic hypertension by the mechanism described by Page were observed.The diagnosis was confirmed by CT and ultrasound,and the patients were treated by means of the hematoma aspiration guided by uttrasound,8 cases were cured.The blood presure in 2 patients with Page's kidney was dropped to normal.No relapse was dernon,vtrated by follLw-up.Author reconlmend this treatment in such cases based on uhrasound and CT finding that rule OUt underlying pathological changes.
2.Efficacy of oxcarbazepine monotherapy on adult patients with temporal lobe epilepsy
Chinese Journal of Postgraduates of Medicine 2016;39(11):992-994
Objective To observe the efficacy of oxcarbazepine monotherapy on adult patients with temporal lobe epilepsy (TLE). Methods Eighty-nine patients with TLE who were admitted to hospital from July 2011 to December 2014 were enrolled in this study. They had underwent surgery. Depending on the postoperative treatment they were divided into oxcarbazepine group (46 patients) and carbamazepine group (43 patients) group. They were treated by oxcarbazepine and carbamazepine after operation. The efficacy and complication were compared. Results The patients in two groups were followed up for 1.5 years. According to Engel grade, the number ofⅠ, Ⅱ, Ⅲand Ⅳ grade in oxcarbazepine group was 29, 10, 5 and 2 patients, in carbamazepine group was 26, 9, 5 and 3 patients, and there was no significant difference (P>0.05). The rate of adverse effect in oxcarbazepine group was 6.5%(3/46), in carbamazepine group was 20.9%(9/43), and there was significant difference (P<0.05). At the end of follow-up, the scores of generic quality of life inventory (GQOLI-74) in oxcarbazepine group was (74.6 ± 2.9) scores, in carbamazepine group was (65.1 ± 3.2) scores, and there was significant difference (t=9.838, P=0.000). Conclusions The efficacy of oxcarbazepine and carbamazepine shows no significant difference in adult TLE.But oxcarbazepine monotherapy has fewer adverse effects and more security.
3.Medical social work and doctor-patient relationship
Chinese Journal of Hospital Administration 2009;25(11):767-769
Description of a multi-perspective view of harmonious doctor-patient relationship holds that medical social workers as a key tie for building such a relationship.It proposed the medical social work strategies for such workers in the face of patients and their families,hospital staff,and hospital management.
4.Disassociation and Determination of the Polyphenols from the Root of Adina rubella Hance
Yong YE ; Hegang GAO ;
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(06):-
Objective: To study the main components of polyphenols from the root of Adina rubelle Hance.Methods: Water extract from the root of Adina rubelle Hance was extracted with acetic ester,then separated by silicage column with differentiation by thin-layer chromatography.Thirdly,the purified fraction was analyzed by GC-MS.Results: Two components were purified,they were catechins compounds.Conclusion: Polyphenols from the root of Adina rubelle Hance were mainly consisted of catechins.
5.Initial study of ultrasonography 5-grade system in the diagnosis of nasopharyngeal carcinoma
Chinese Journal of Ultrasonography 2013;22(11):950-953
Objective To explore the application of ultrasonography (US) 5-grade system in the diagnosis of nasopharyngeal carcinoma(NPC).Methods A total of 150 patients suspected of having NPC underwent ukrasonography and MR imaging.All the lesions were scored according to the two different methods.Pathological results were made the golden criteria.The diagnosis accuracy of ultrasonography and MR imaging for NPC was evaluated using receiver-operating curve (ROC) analysis by Medcalc software.Results Both ultrasonography and MR imaging exhibited a good diagnostic performance for NPC with area under the curve (AUC) values of 0.958 and 0.987,respectively.The AUC difference of the two methods were statistically significant(Z =2.827,P =0.005).Conclusions Ultrasonography 5-grade system was an initial quantitative criterion for nasopharyngeal carcinoma diagnosis.The diagnosis accuracy was high although lower than MRI.But it could provide an overall economical and convenient complementary technique for clinical diagnosis.
6.Thrombosis and thromboprophylaxis during chemotherapy in patients with cancer
Journal of International Oncology 2012;39(2):120-123
Many datas show that thrombosis related events during chemotherapy in patients with cancer increase obviously.Thromboprophylaxis in patients receiving chemotherapy has been shown to not only improve the hypercoagulable states and effectively prevent thrombosis,but also have the potential antitumor effect and prolong the patients over survival.
7.Application value of serum tumor markers in diagnosis of pancreatic adenocarcinoma in the elderly
Chinese Journal of Geriatrics 2013;32(8):840-842
Objective To explore the clinical value of serum tumor markers including CEA,AFP,CA199,CA125,CK19,CA242 and CA724 in diagnosis of pancreatic adenocarcinoma in the elderly.Methods Totally 158 elderly and 102 middle-aged patients with pancreatic adenocarcinoma were selected.Pancreatic adenocarcinoma in all patients were confirmed by pathological examination,cytological examination and CT.100 elderly and 100 middle-aged patients with benign diseases were selected as control groups.The levels of serum tumor markers were detected and their sensitivities and specificities were calculated and compared between groups.Results The levels of serum CEA,CA199,CA125,CK19,CA242 and CA724 were higher in elderly patients with pancreatic adenocarcinoma than in the elderly control group [(70.9±11.4) g/L vs.(1.6±0.4) g/L,(158.9±19.1)U/mlvs.(12.6±3.2)U/ml,(53.9±15.4)U/mlvs.(11.6±1.1)U/ml,(70.2±16.3)U/ml vs.(1.4±0.2)U/ml,(96.4±18.5)U/ml vs.(7.9±2.2)U/ml,(57.6±13.6)U/ml vs.(4.4± 0.6)U/ml,t=26.13,31.63,17.57,19.03,20.95,15.59,respectively,all P<0.05].The sensitivities of serum CEA,AFP,CA199,CA125,and CA242 were higher in the elderly patients than in the middle aged patients (61.72% vs.48.69%,19.56% vs.4.13%,80.31% vs.69.55%,70.21% vs.46.77%,75.24% vs.59.44%,x2=4.28,12.63,3.94,14.32,7.23,respectively,all P<0.05).The specificities of serum CEA,AFP,CA199,CA125,and CA242 had no significant differences between the elderly and middle aged patients (all P>0.05).Conclusions Serum tumor markers may provide effective reference for the clinical diagnosis of pancreatic adenocarcinoma in the elderly,which has important value for pancreatic adenocarcinoma control and reversal.
8.Measurement of Renal Volume of Pregnant Women for the Predictiveness
Chinese Journal of Ultrasonography 1995;4(5):209-211
The measurement of renaI volume by ultrasound was carried out in 488 women with sigleton pregnahey.Sixty-eight women had infants with the intrauterine Browth retardation(IUGR).The average of renal volume in nofmal pregnant females and females with IUGR increased 57.2% and 8.4% respectively during trimester.Hence,the neonatal weight outcomes were cortelated with the renal volume in their mothers.The specficity of measurement was 96%,and the sensitivity was 65%.The sensitivety was influenced by type of IUGR and individual difference of renal vohme.The positive predictive vaIue was 74%.
9.Analysis on present situation of patent creativity for Chinese materia medica in China
Chinese Traditional and Herbal Drugs 1994;0(06):-
According to the relative data of the patents awarded in the field of Chinese materia medica (CMM) announced by State Intellectual Property Office of P. R. China during 1998-2003, the amounts of CMM patents awarded with different types, compounds and active constituents, and service and non-service patents of CMM were compared and analysed. The amounts of inventive CMM patents have been more than that of the patents of utility model and design, the patents of CMM compound have greatly exceeded the patents of active constituent of CMM. Non-service patents of CMM has absolute predominance compared with the service patents. However, percentage of patents of active constituents and service patents of CMM are important targets to measure the creativity of CMM patents. This difference has reflected the present situation of CMM in China-lack of creativity. Based on the authentication of CMM creative patent, the cause of the above-mentioned situation has been analysized, and that our Patent Law should perfect the criterions of the CMM creative patent has been proposed so as to encourage the individuals and enterprises to advance the creativity of CMM in skills furtherly and strengthen the ability of protecting Intellectual Property Right and power of international competition for CMM.
10.Observation on the efficacy and bacteria clearance rate of imipenem and cilastatin sodium on elderly patients with severe bacterial infection
Chinese Journal of Biochemical Pharmaceutics 2017;37(5):347-349
Objective To investigate the clinical efficacy of imipenem and cilastatin sodium on the clinical efficacy of elderly patients with severe bacterial infection, and to observe the clearance rate to different floras.MethodsA total of 206 elderly patients with severe bacterial infection as the research object in our hospital outpatient treatment, were divided into control group and observation group, the patients were collected with sputum, blood and urine samples sent for bacterial culture.All patients were given positive treatment and nursing care, the observation group was given imipenem and cilastatin sodium treatment,the control group was given cefotaxime sodium treatment.The clinical efficacy, bacterial clearance and adverse reactions of the two groups were recorded and compared.ResultsThe total efficiency rate was 91.26% in the observation group, and 79.61% in the control group.The number of effective cases was significantly higher in the observation group than in the control group (P<0.05), the number of ineffective cases was significantly lower than that of the control group (P<0.05);The bacterial clearance rate was 85.71% in the observation group, and 43.33% in the control group, the clearance rate of Bauman Acinetobacter, Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus was significantly higher in the observation group than in the control group (P<0.05).Through the detection of adverse reactions showed that the observation group and the control group after treatment, few patients mild symptoms of nausea and vomiting and itching rash, on the occurrence of adverse reactions of the two groups of patients were compared, the difference was not statistically significant.ConclusionFor elderly patients with severe bacterial infection with imipenem and cilastatin sodium for treatment, the effective rate is high and can timely remove a variety of pathogenic bacteria, and rare adverse reactions, high safety, worthy of clinical application.