Introduction: Diarrhea is defined as a person excretes more than three times in 24 hours with pathological impurities of more than 10 mg/kg per day. According to the fact sheets of the World Health Organization in 2019, diarrhea is the second leading cause of death among children under 5 years of age. Researchers suggest that about 50 percent of infantile diarrhea occurs in temperate countries and it reaches almost 80 percent in winter which is mainly caused by rotavirus. While immunization is the most effective way to prevent rotavirus infection, there were two types of rotavirus vaccines that have been licensed and available on the global market since 2006. Rotavirus immunization in young children is a safe and effective public health method for controlling rotavirus infection which therefore can reduce childhood morbidity and mortality. Study aim: To study the incidence, clinical manifestations, and complications of rotavirus among children hospitalized with acute diarrhea. Methodology: The study will be conducted using the observational method including descriptive analysis. Statistical data for 2018-2020 will be obtained and analyzed from the pediatric wards of the “Gurvan Gal” hospital. Children diagnosed with rotavirus diarrhea who meet the criteria to be included in the study will be selectively sampled with further analysis of the incidence, clinical features, toxicity, and dehydration of acute diarrhea according to the medical history. Results Universal immunization is important to significantly reduce rotavirus-associated diarrhea, thereby reducing infection and the risk of disease in infants and young children.

Introduction: Electrolyte values are measured by two different analyzers: arterial blood gas (Point of care) and auto-analyzers. Those two has different methods to measure electrolytes and have several pros and cons. We evaluated if there was agreement between whole blood electrolytes measured by a point-of-care device and serum electrolytes measured using indirect ion-selective electrodes. Materials and methods: An observational cohort study was conducted in 50 paired venous samples from patients admitted in Gurvan gal central hospital. Those were analyzed on OPTC blood gas devise and Roche c-501 auto-analyzer. Statistical analyses were performed using paired t-test and persons’ correlation test. Results: Sodium mean range was 138.54 mmol/l (SD=3.69) by blood gas analyser, but by the automated analyser mean range was 140.75 mmol/l (SD=4.45). Mean difference of the normal sodium group was 1.77 (SD=1.65, p=0.039), and hyposodium group was 4.4 (SD=0.33, p=0.007). Pottasium mean range was 3.13 mmol/l (SD=0.53) by blood gas analyser, but by the automated analyser mean range was 4.42 mmol/l (SD=0.45). Mean difference of the normal sodium group was 0.18 (p<0.001), and hypokalemi group was 1.44 (p<0.001). Conclusion Clinicians should be aware of the difference between whole blood and serum electrolytes. A correction factor needs to be determined at each laboratory.

The purpose of this study is to clarify success factors for desirable relationship between buyer and supplier in elementary school. Therefore, the survey questionnaire consisted of general background, past success, success difference, buyer-supplier relationship characteristics(trust, supporting status, communication behavior, conflict resolution techniques, supplier selection process). The subjects were 66 dieticians of elementary school in Inchon. The statistical analysis of data was completed using SPSS program. The results were summarized as follows : Average total cost/day per one person 1,156Won. The number of suppliers per one school were 6. 92.3% of the subjects were in favor of private contract, regarding contract methods of purchasing food materials. For the past success, degree of satisfaction about past their supplier showed 3.49 score. The present success difference was shown higher than the past success. There was significant correlation between the past success and the present success difference. Trust about suppliers showed 3.40score. Supplying companies hardly support for buying school. Among information quality(timely, accurate, adequate, complete, credible), timely and complete showed lower score than the other kind of elements. Among the buyer-supplier relationship characteristic elements, only trust correlated with satisfaction about suppliers significantly. Among the conflict resolution techniques, joint problem solving and persuasive attempts were often made use of by subjects. The supplier selection criteria were shown quality(7.47), supplier's capabilities(6.46), management plan(6.00), price(5.73), scale(5.48), assets(5.27), considers delivery(4.76) and technology(2.39). As results, trust was needed for the desirable relationship between buyers and suppliers. This study has some limitations. The data in this study were collected from only buyer. It is more desired to acquire data from suppliers also.
Humans ; Incheon ; Joints ; Lunch* ; Negotiating ; Nutritionists ; Patient Selection ; Problem Solving ; Surveys and Questionnaires

Background:Laboratory test are done on clinical specimens in order to get information about the health of a patient as pertaining to the diagnosis, treatment and prevention of disease. Laboratory test gives 70% of information to get a right diagnosis. By some study, physiological factors such as diet, stress, exercise and sample collection techniques are influencing 32%-75% of test accuracy and reliability. That is why we want to studyhow nurses follow standard of sample collection techniques in UB.Our study conducted in 5 different hospitals. We observed nursesway of collecting sample from 150 patientsResult:Nurses did not identify patients ID in 80% of patients and did not ask test preparation and diet of 100%. They prepare necessary items to blood draw 95%. Also nurses did not fully follow blood draw standard in such way: hand sterilization, asepticize place of puncture and using bandage. Conclusion:Nurses don’t follow standard of draw blood from vein and did not clarifies patients test preparation. Pre-analysis process is the most influencing factor in the test result. So we have to train nurses to follow their standard of sample collection procedure.

BACKGROUND: The third-generation bio-intact parathyroid hormone (PTH) (1–84) assay was designed to overcome problems associated with the detection of C-terminal fragments by the second-generation intact PTH assay. The two assays have been compared primarily among dialysis populations. The present study evaluated the correlations and differences between these two PTH assays among patients with chronic kidney disease (CKD) stages 3 to 5 not yet on dialysis. METHODS: Blood samples were collected from 98 patients with CKD stages 3 to 5. PTH concentrations were measured simultaneously by using the second-generation - PTH intact-STAT and third-generation bio-intact 1–84 PTH assays. Other serum biomarkers of bone mineral disorders were also assessed. CKD stage was calculated by using the CKD-Epidemiology Collaboration (EPI) formula. RESULTS: Serum bio-intact PTH concentrations were strongly correlated but significantly lower than the intact PTH concentrations (r=0.963, P<0.0001). This finding was consistent among CKD stages 3 to 5. PTH concentrations by both assays (intact and bio-intact PTH) positively correlated with urea (r=0.523, r=0.504; P=0.002, respectively), phosphorus (r=0.532, r=0.521; P<0.0001, respectively) and negatively correlated with blood calcium (r=−0.435, r=−0.476; P<0.0001, respectively), 25(OH) vitamin D, (r=−0.319, r=−0.353; respectively, P<0.0001) and the estimated glomerular filtration rate (r=−0.717, r=−0.688; P<0.0001, respectively). CONCLUSIONS: Among patients with CKD stages 3 to 5 not on dialysis, the bio-intact PTH assay detected significantly lower PTH concentrations compared with intact PTH assay. Additional studies that correlate the diagnosis and management of CKD mineral and bone disorders with bone histomorphometric findings are needed to determine whether bio-intact PTH assay results are better surrogate markers in these early stages of CKD.
Biomarkers ; Calcium ; Cooperative Behavior ; Diagnosis ; Dialysis ; Glomerular Filtration Rate ; Humans ; Hyperparathyroidism, Secondary ; Miners ; Parathyroid Hormone ; Phosphorus ; Renal Insufficiency, Chronic* ; Urea ; Vitamin D

UNLABELLEDOBJECTIVE; To observe clinical therapeutic effect and the mechanism of drug-separated moxibustion at the navel for delaying aging.

METHODSSeventy-one cases were randomly divided into 3 groups. The group of drug-separated moxibustion at the navel (n=30) were treated with drug-separated moxibustion at the navel, twice each week; the acupuncture group (n=21) with acupuncture at Shenshu (BL 23) and Taixi (KI 3) as main points once each day; the western medicine group (n=20) with oral administration of vitamin E capsules, 0. 1 g each time, twice daily. Their clinical therapeutic effects, and changes of cumulative scores, serum SOD activities and MDA contents after treatment were compared among the 3 groups.

RESULTSAfter treatment, clinical symptoms in the 3 groups very significantly improved (P < 0.01), with the group of drug-separated moxibustion at the navel more significantly improved (P < 0.01); in the 3 groups, SOD activities significantly increased (P < 0.01) and serum MDA contents significantly decreased (P < 0.01), and SOD activity and MDA content in the group of drug-separated moxibustion at the navel were not significantly different from those in the acupuncture group (P > 0.05), but significantly different from those in the western medicine group (P < 0.05).

CONCLUSIONThe drug-separated moxibustion at the navel can significantly delay aging.

Acupuncture Therapy ; methods ; Aged ; Aging ; Female ; Humans ; Male ; Malondialdehyde ; blood ; Middle Aged ; Moxibustion ; Superoxide Dismutase ; blood

BACKGROUND: The limbe is a traditional Mongolian instrument that has been used since the ancient times, and the performer uses a unique method called circular breathing to play it. The circular breathing technique is significant heritage of the Mongolian people, and has been recognized by UNESCO World Heritage. Aim: To study the anatomy and physiology that take part in playing the Mongolian limbe with the circular breathing technique. METHODS: We have studied 20 flutists using case control study method. The flutists’ change of gas compound in blood have been studied with a gas analyzer after playing for 10 minutes with the circular breathing. When the flutists play it with circular breathing, the anatomical structures and their function have been studied and documented by an endoscopy, X-ray and a 320 row area detector CT. RESULTS: The 20 participants were between the ages of 22-56 with the circular breathing experience of 2 to 37 years. After playing the instrument for 10 minutes, we found the following results: 67.7% of the participants developed alkolosis, 23.5% hypocapnia, 5.9% hypercapnia, 94.1% hypoxia, and all participants’ oxygen saturation decreased. The lingual muscles, upper and under muscles of the hyoid bone, larynx and vocal cords are the main structures of the circular breathing. CONCLUSION: Playing Mongolian limbe with the circular breathing leads to hypoxia, thus the circular breathing stops. It is important to note that this process does not depend on flutist’s age, their practice time, and their personal technique. However, we concluded that the time of performance without interruption depends on individual’s physiological characteristics. In order to study the issues of anatomy and physiology that take part in playing the Mongolian limbe with the circular breathing, we have studied 20 flutists using case control study method. The flutists’ change of gas compound in blood have been studied with a gas analyzer after playing 10 minutes by the circular breathing. When the flutists play it with circular breathing, the anatomical structures and their function have been studied and documented by an endoscopy and X-ray. The lingual muscles, upper and under muscles of the hyoid bone, larynx and vocal cords take part in the circular breathing by limbe as a main rule. Playing Mongolian limbe with the circular breathing lead to hypoxia thus the circular breathing stops. This process does not depend on flutist’s age, their practice time, and their private technique. But we concluded that how long time they play it without interruption depends on individual’s physiological singularity.

This study was designed to evaluate the contractile and relaxing responses of abdominal aorta in renovascular hypertension accompanied with essential hyper- tension and to examine the effect of angiotensin II receptor blocker(losartan). An experimental renovascular hypertension accompanied with essential hypertension model was established by clipping the left renal artery of spontaneously hypertensive rats(SHR). These rats were then divided into two groups of which one was given losartan during the one week postopertion before being terminated. Ring preparations of the abdominal aorta were obtained one week after the operation. The contraction of abdominal aorta strips were induced by high potassium or norepinephrine, and relaxation produced by acetylcholine or sodium nitroprusside. The contractile and relaxing responses were recorded and compared with data obtained from the control group. In the second experiment, the rats received angiotensin Il blocker(LRAO group), losartan in the drinking water for 7 days after the induction of the renal artery stenosis operation. Then, the contractile and relaxing responses were evaluated by the same method. The following results were obtained; 1) The contractile responses to the high level potassium solution and norepinephrine in renal artery occlusion(RAO) group were significantly increased compared with SHR group(p<0.05). 2) The contractile reponses to the high level norepinephrine in LRAO group were similar to that of SHR control group. However, there was no remarkable differences for high potassium. 3) The relaxing responses to the acetylcholine were significantly reduced in the RAO group compared with the SHR group. However, there was no remarkable differences for sodium nitroprusside. 4) There were no significant differences in the acetylcholine or sodium nitroprusside induced vasodilation response between the LRAO group and SHR group. From the above result, it is suggested that re- novascular hypertension in spontaneously hypertensive rats might induce changes of vascular responses and this effects may be concerned with endothelium-dependant mechanism. And angiotensin II receptor blocker rnay prevent the development of abnormal endothelium-dependent relaxation in renovascular hypertension accompanied with essential hypertension by maintaining endothelial function.
Acetylcholine ; Angiotensin II* ; Angiotensins* ; Animals ; Aorta, Abdominal* ; Drinking Water ; Hypertension ; Hypertension, Renovascular* ; Losartan ; Nitroprusside ; Norepinephrine ; Potassium ; Rats ; Rats, Inbred SHR* ; Receptors, Angiotensin ; Relaxation ; Renal Artery ; Renal Artery Obstruction ; Vasodilation