1. Multi-level analysis on factors affecting the adherence to early antithrombotic therapy among people with acute ischemic stroke
Xu BAI ; Yanping SONG ; Xinrui LYU ; Fuyang RAO ; Wei QIN ; Xinying HUANG ; Zixiao LI ; Baohua LIU ; Yong JIANG
Chinese Journal of Epidemiology 2019;40(6):610-615
Objective:
To explore the patient and hospital related determinants of adherence to early antithrombotic therapy among patients with acute ischemic stroke (AIS).
Methods:
AIS patients aged 50 years old or above who were eligible for early antithrombotic therapy, were included from the China National Stroke Registry Ⅱ (CNSR Ⅱ) project. Characteristics related to patients and hospitals were collected. Univariate analysis method was conducted to explore the correlation between hospital or patient-related determinants and early antithrombotic therapy. A 2-level logistic regression model was set up to identify patient and hospital-related variables that were associated with the adherence to early antithrombotic therapy, with patient as level 1 and hospital as level 2.
Results:
A total of 16 910 patients were included in the study, with 14 332 (84.75%) of them having received early antithrombotic therapy. Results from the univariate analysis showed that the patient determinants to early antithrombotic therapy would include age, type of health insurance, average income and history of dyslipidemia. Hospital determinants would include factors as: level and region of the hospital, academic status, with/without stroke unit, quality control on single disease and the percentage of neurological beds in total beds (