Hydroxyapatite (HAP) formation on the surface of the degradable polyamides implant by a coating technology was studied. A suspension of HAP-glutin-acetic acid was prepared and brushed on the surface of the implant at room temperature. Scanning electron microscopy (SEM), X-ray diffractometry (XRD) and Fourier transform infrared spectroscopy (FT-IR) were employed to study the composition and the microstructure of the coating. The results obtained indicate that the main composition of coating is crystal HAP, its structural formula is Ca10(PO4)6(OH)2. So the coating has bioactivity. The coating has also small pores, which can stimulate bone regrowth and adsorption of other bioactive materials or mediine. This technology is an effective method to improve medical performance of the polyamides implant.
Bone Substitutes ; Coated Materials, Biocompatible ; chemical synthesis ; chemistry ; Durapatite ; chemical synthesis ; chemistry ; Nylons ; Prostheses and Implants

Objective Polymorphic microsatellite markers developed for Apodemus peninsulae can enrich its genetic data and lay a foundation for genetic quality control and gene mapping.Methods Microsatellite loci were screened based on the genome sequence of Apodemus peninsulae,and microsatellite primers were identified.The genetic diversity of the population was analyzed by multiplex PCR.Results Thirty microsatellite markers were successfully developed and evaluated using 60 samples of Apodemus peninsulae.A total of 152 alleles were detected,with an average of 5.067 alleles per locus.The average observed heterozygosity was 0.592.The average Shannon index was 1.265.The average polymorphism information content was 0.598.Conclusions Based on the microsatellite loci developed in this study,the genetic diversity of Apodemus peninsulae can be effectively analyzed,laying a foundation for establishing genetic quality standards and detection method.