1.Numerical study on adjusting parameters to improve gaze estimation using planar approximations from electro-oculogram signal voltage ratios
Biomedical Engineering Letters 2019;9(2):181-187
Gaze or eye movements are used as a communication interface in daily life. Herein, we developed a simple method for gaze estimations based on planar approximations of voltage ratios calculated from multiple electro-oculogram signals not affected by drift phenomena, which decrease accuracy. Subsequently, we conducted simulations using an eyeball battery model and investigated the effects of adjusting electrode arrangements, determination coefficients for planar approximations of voltage ratios, and threshold values for angles between simultaneous linear equations, to improve the estimation accuracy and decreased the number of required electrodes. Numerical experiments were used to identify arrangements of six electrodes with errors that were approximately 5° less than those of nine-electrode L-shaped arrangements, indicating improved estimation accuracy with fewer electrodes.
Electrodes
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Eye Movements
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Methods
2.Long-term outcome after surgery in a patient with intestinal Behçet’s disease complicated by myelodysplastic syndrome and trisomy 8
Yuki MORI ; Fumihiko IWAMOTO ; Yasuaki ISHIDA ; Toru KUNO ; Shoji KOBAYASHI ; Takashi YOSHIDA ; Tatsuya YAMAGUCHI ; Tadashi SATO ; Makoto SUDO ; Daisuke ICHIKAWA ; Nobuyuki ENOMOTO
Intestinal Research 2020;18(4):469-475
Behçet’s disease (BD) is a multisystem inflammatory disease of unknown origin. Rarely, BD occurs together with myelodysplastic syndrome (MDS). Interestingly, it is speculated that these are not simple coexistence but that the etiology of intestinal BD is at least partly derived from MDS itself. Furthermore, there is a relationship between MDS in patients with intestinal BD and trisomy 8. Immunosuppressive agents alone are insufficient to control MDS-associated BD, and many of these patients die of infection or hemorrhage. Surgery is considered for intestinal BD patients who are unresponsive to medical treatment or those with bowel complications such as perforation or persistent bleeding. We report a case of intestinal BD associated with MDS and trisomy 8. The patient was unresponsive to oral steroids and immunosuppressive treatment; the patient improved by surgical repair of a bowel perforation. Five years after the surgery, the patient is free of recurrence and not on medication. Our experience suggests that surgery may provide an effective therapeutic option for the treatment of MDS-related BD.