1.The interventional therapy of airway dysplasia via bronchoscopy
Xin ZHANG ; Zhou FU ; Gang GENG
International Journal of Pediatrics 2016;43(12):934-937
Bronchoscopy is an indispensable method to diagnose and treat children with respiratory dis-ease treatment,it′s the foundation of pediatric interventional pulmonary procedures. Because of the widely use and the steady accumulation of clinical experience,the value has been consistently affirmative. This review de-scribes the interventional therapy of airway dysplasia via bronchoscopy.
2.The effect of notch signaling in chondrocytes differentiation
Gang LIU ; Lei ZHANG ; Shijie FU
Journal of Medical Postgraduates 2016;29(10):1111-1115
Notch signaling is an important evolutionarily conserved pathway involving the fate of cells translation. Additional?ly, this pathway also plays an important role in cartilage formation and maintenance of chondrocytes phenotype, regulation of the prolif?eration, maturation and balance of cartilage matrix metabolism. This paper reviews the composition and activation process of notch sig?naling, and its specific role in cartilage formation.
3.Role of Southwick angle and Klein line in the diagnosis of slipped capital femoral epiphysis
Yijing XU ; Gang FU ; Jianli ZHANG
Orthopedic Journal of China 2006;0(09):-
[Objective]To evaluate the role of Southwick angle and Klein line in the diagnosis of slipped capital femoral epiphysis (SCFE). [Methods]Forty-two cases of SCFE were treated by Russell traction and screw or pins fixation in situ from 1995 to 2006. The hip anteroposterior and frog-lateral radiographs were reviewed to measure the occurrence of metaphyseal change,the Southwick angle and the Klein line.[Results]The metaphyseal changes occurred in all cases. The Southwick angles were reduced with the severity of SCFE. The positive ratio of Klein line was higher in the lateral radiographs,but lower in the anteroposterior radiographys.[Conclusion]The Southwick angle and Klein line play an important role in the diagnosis of SCFE. The lateral radiography should be emphasized in the diagnosis of SCFE.
4.Research progress of trans-cinnamaldehyde pharmacological effects.
Li-qing ZHANG ; Zhan-gang ZHANG ; Yan FU ; Ying XU
China Journal of Chinese Materia Medica 2015;40(23):4568-4572
Trans-cinnamaldehyde, the main component of volatile oil from cassia twig or Cinnamomum cassia, which is a traditional Chinese herbal medicine. Trans-cinnamaldehyde is a kind olefine aldehyde of organic compounds and has many pharmacological properties, such as anti-inflammatory, anti-tumor, anti-bacterial, antidiabetic, anti-obesity, and neuroprotection etc. The compound has preventive and therapeutic effects on the nervous system, cardiovascular, cancer, diabetes and other diseases. Trans-cinnamaldehyde, as a preventive care of nature medicine, has great clinical and market potential. This paper gives a review about the pharmacological effects and mechanism of trans-cinnamaldehyde researched in the latest five years. We hope to provide some basic information for further research on trans-cinnamaldehyde.
Acrolein
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analogs & derivatives
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chemistry
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pharmacology
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Animals
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Cinnamomum aromaticum
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chemistry
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Drugs, Chinese Herbal
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chemistry
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pharmacology
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Humans
7.Distribution and Drug Resistance Detection of Pathogens from Nosocomial Lower Respiratory Tract Infection in Wards of Respiratory Disease
Bo ZHANG ; Gang LIU ; Weiling FU ; Xiaobing ZHANG
Chinese Journal of Nosocomiology 2005;0(11):-
OBJECTIVE To determine the distribution and drug resistance characteristic of pathogens from(nosocomial) lower respiratory tract infection in wards of respiratory disease and direct clinical doctors to select(antibiotics) correctly.METHODS A total of 159 strains of pathogens from sputum samples of patients with(respiratory) tract infection in wards of respiratory disease in our hospital were identified and the drug resistance tests were performed.In addition,ESBLs-producing G~-bacilli were also detected.RESULTS Among 159 strains from respiratory tract infection,G~-bacilli rated the top one(69.8%),The most common pathogens were Pseudomonas aeruginosa(14.5%),Klebsiella pneumoniae(13.8%),Acinetobacter baumannii(10.7%),(Staphylococcus) aureus(10.7%),and fungi(9.4%).10.8% G~-bacilli produced ESBLs.CONCLUSIONS G~-(bacilli) are the main infectious pathogens in respiratory infection and antibiotic resistance rates continue to(evolve).Therefore bacterial culture and antibiotic susceptibility tests are very important to select antibiotics(correctl)y for treatment of the infections in wards of respiratory disease.
8.Mild hypothermia reduces and delays cell apoptosis in the hippocampal CA_1 region following ischemia-reperfusion injury
Fu-Sheng ZHANG ; Gang ZHANG ; Rui-Guo DONG ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(09):-
Objective To investigate the protective effects of mild hypothermia on cells in the CA_1 region of the hippocampus in gerbils following global ischemia-reperfusion injury(IRI),and to explore their mechanism. Methods IRI models were established in 75 gerbils.Any changes in TUNEL positive cells and the expression of Bax and Cytochrome C were then observed in normothermic(N) ,hypothermic(H)and sham(S) groups through immu- nohistochemistry methods.Results In the H group(as compared with the N group)apoptotic cells in the CA_1 sub- field of the hippocampus significantly decreased.The expression of Bax and Cyt C at 3 h,6 h and 1 d were de- creased,and the expression fastigium was delayed.Conclusion Mild hypothermia can moderate and delay cell ap- optosis,and its mechanism might be related with reducing and delaying the expression of Bax and Cyt C released by mitochondria.
10.Standard substance for arsenic analysis in freeze-dried human urine.
Fu-gang ZHANG ; Wei ZHAO ; Chun-ling LI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2010;28(2):117-119
Arsenic
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urine
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Freeze Drying
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standards
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Humans
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Reference Standards
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Urinalysis
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methods
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standards