3.Research progress of the structure and function of blood-spleen barrier
International Journal of Surgery 2008;35(12):829-832
Blood-spleen barrier is an important part of the structure and function of spleen.In recent years,blood-spleen barrier gradually arouse people's attention and was often reported.This review focuses on the research progress of the structure and function of blood-spleen battier.
4.Current situation and prospect of liver transplantation in China.
Chinese Journal of Surgery 2007;45(15):1009-1011
China
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Humans
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Liver Transplantation
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methods
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mortality
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trends
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Survival Rate
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trends
5.Research progresses on K-RAS mutation of non-small cell lung cancer
Basic & Clinical Medicine 2010;30(2):212-214
Mutated K-RAS is found in 15%~30% NSCLC patients, the mutations of K-RAS and EGFR are mutually exclusive,K-RAS mutations have poor sensitivity to EGFR-TKIs. The response of C-225 is not restricted to mutated K-RAS, NSCLC patients with K-RAS mutations are associated with unfavorable prognosis. A number of different approaches such as Ftase inhibitors, RAF inhibitors, MEK inhibitors aimed at abrogating K-RAS activity to improve clinical response have been explored in clinical trials.
6.Progress and hot topics in clinical management of desmoid tumor
China Oncology 2010;20(3):227-231
Desmoid tumor also known as aggressive fibromatosis,are rare fibroblastic tumors which are derived from deep fascia planes or muscuofascia structures.Resectable extra-abdominal and abdominal desmoid tumor should always be treated with the aim of achieving a negative margin through wide radical resection with margins above 2 cm.Ifthis is not feasible,function-sparing surgical resection is suggested.Adjuvant radiation should be considered for patients with positive margins,recirrent tumors or unresectable diseases.Intra-abdominal desmoid tumor is common in patients with familial adenomatous polyposis.It has a high recurring rate after surgical resection and therefore a high dosage of tamoxifen and sulindac are recommended as first-line treatment.Due to the variable nature of the outcome and vague reaction to drug therapy,individualized treatments,including the wait and see policy,has been widely investigated and thought to be a promising strategy for the future.
7.Effects of endoscopic surgery on patients with chronic rhinosinusitis with bronchial asthma.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(19):1501-1504
OBJECTIVE:
To investigate the efficacy of endoscopic sinus surgery (ESS)-based multidisciplinary therapy for patients with chronic rhinosinusitis (CRS), nasal polyps and bronchial asthma.
METHOD:
The study included 32 patients with CRS, nasal polyps and bronchial asthma who received ESS, besides surgery, who also used glucocorticoid inhalation, nasal spray and nasal irrigation perioperatively. The evaluation of the treatment was performed 3 years post after ESS.
RESULT:
In the 32 cases treated with ESS, 19 cases were cured, 9 cases were improved, 4 cases were inefficient by the treatment. The cure rate was 87.5%. The asthma symptoms were improved in 9 patients (P < 0.01), compared to 2 before surgery. The numbers of patients with improved symptoms were increased from 2 before the surgery to 9 after the surgery.
CONCLUSION
As the main treatment, endoscopic si- nus surgery was effective on CRS with asthma.
Asthma
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surgery
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Chronic Disease
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Endoscopy
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Humans
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Nasal Lavage
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Nasal Polyps
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surgery
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Paranasal Sinuses
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Rhinitis
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surgery
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Sinusitis
8.New areas of laboratory medicine in the 21st century:terahertz laboratory medicine
Chinese Journal of Laboratory Medicine 2015;38(1):1-3
The terahertz laboratory medicine (THz-LabMed) is an intergrated cross-frontier field which involves multi-disciplinary including medicine,biology,biomedical engineering,physics,optics,computer science,information and materials.Using THz technologies for label-free detection and analysis of biomedical macromolecules,cell and tissues,the THz-LabMed is also the core components of terahertz biomedine (THz-BioMed) which focuses on the biomedical application of THz technologies.THz label-free detection is being paid more and more attention because of its unique advantages worldwide and becomes a hot spot for the application of THz wave technology and methods in life science.Application of THz technology in biomedicine involves many fields globally,including disease diagnosis,recognition of protein status,label-free DNA sequencing,mechanism for absorption differences of biological tissue to THz wave,and radiation influence on biological samples and biological process.THz-LabMed is the global synchronized research in THz-BioMed field in China.It is important to seize the opportunities to develop new disciplines of laboratory medicine.
9.Comparison of Hysteroscopic and Laparoscopic Treatment for Endogenous Type Cesarean Section Scar Pregnancy
Chinese Journal of Minimally Invasive Surgery 2015;(10):894-896
Objective To evaluate the safety and feasibility of hysteroscopy in the treatment of endogenous type cesarean section scar pregnancy (CSP). Methods Clinical data of 58 cases of CSP from August 2012 to February 2014 in our hospital were analyzed retrospectively.Thirty-one cases were treated by hysteroscopy,while 27 cases were treated by laparoscopy.The intraoperative blood loss,operation time,postoperative hospital stay,postoperative drainage of uterine cavity,β-hCG level resolution time and time to menstruous restoration were compared between the two groups. Results The intraoperative blood loss,operation time,length of hospitalization after operation,and time to menstruous restoration were statistically lower in the hysteroscopy group than those in the laparoscopy group [(109 ±59)ml vs.(143 ±63)ml,t =-2.121 ,P =0.038;(43.7 ±17.5)min vs.(100.8 ±18.8)min,t =-1 1 .974,P =0.000;(3.8 ±0.7)d vs.(4.5 ±0.6)d,t =-4.057,P =0.000;(43.8 ±3.9)d vs.(45.9 ±3.8)d,t =-2.070,P =0.043].There were no significant differences in postoperative drainage of uterine cavity and β-hCG level resolution time between the two groups [(22.1 ±2.8)ml vs.(23.6 ±3.2)ml,t =-1 .904,P =0.062;(20.5 ±7.7)d vs.(22.9 ±9.3)d,t =-1 .075,P =0.287]. Conclusion Hysteroscopy has advantages of less intraoperative blood loss,shorter hospitalization time and quicker recovery in the treatment of endogenous type CSP.