No abstract available.
Focal Nodular Hyperplasia*

No abstract available.
Focal Nodular Hyperplasia* ; Humans ; Male*

No abstract available.
Adult ; Female ; Focal Nodular Hyperplasia/*pathology ; Humans

Recent advances in imaging technologies have offered us a great chance to detect a variety of focal liver lesions. Accordingly, it is of paramount importance to determine whether these focal liver lesions are malignant or nonmalignant. Some benign hepatic tumors mimicking hepatocellular carcinoma typically develop from either regenerative or dysplastic/neoplastic processes. The most common benign hepatic solid tumors that are not of vascular origin include focal nodular hyperplasia and hepatocellular adenoma. A majority of patients with benign hepatic tumors are often asymptomatic and require no specific treatment. However, surgical resection may be infrequently needed for cases with clinical symptoms or malignant potential. This review will touch on the epidemiology, pathogenesis, clinical features, diagnosis, and management of focal nodular hyperplasia and hepatocellular adenoma.
Adenoma, Liver Cell ; Carcinoma, Hepatocellular ; Focal Nodular Hyperplasia ; Humans ; Liver

Thyroid carcinogenesis is traditionally thought to originate 'de novo'. However, it is debatable whether a malignant transformation can possibly arise from a benign thyroid nodule, as suggested for the malignant transformation of a thyroid adenoma. To the best of our knowledge, no studies have been performed addressing the malignant transformation of nodular hyperplasia in the thyroid gland. Here, we report a case of nodular hyperplasia with focally malignant degeneration.
Carcinogenesis ; Cell Transformation, Neoplastic ; Focal Nodular Hyperplasia ; Hyperplasia* ; Thyroid Gland* ; Thyroid Neoplasms ; Thyroid Nodule

Adult ; Aged ; Female ; Focal Nodular Hyperplasia ; Humans ; Male ; Middle Aged ; Young Adult

We present here the radiological findings of a rare case of multiple focal nodular hyperplasia that was associated with portal vein atresia and portopulmonary hypertension in a young woman. This case illustrates and supports the pathophysiological hypotheses that were previously proposed for the coexistence of these three abnormalities.
Adult ; Female ; Focal Nodular Hyperplasia/*radiography ; Humans ; Hypertension, Portal/*complications ; Hypertension, Pulmonary/*complications ; Portal Vein/*abnormalities

Primary liver tumors are uncommon in childhood, with a relative frequency of 3% of childhood tumors. Seventy three cases of pediatric primary liver tumors which were operated on at single institution between 1986 and 2002 were reviewed. There were 37 cases of hepatoblastoma, 11 hepatocellular carcinomas, 6 undifferentiated (embryonal) sarcomas, and 1 mixed germ-cell tumor in malignancies. Benign tumors constitute only 24.6% of liver tumors, including 7 hemangioendotheliomas, 5 mesenchymal hamartomas, 3 congenital cysts, and one each with focal nodular hyperplasia and hemangioma. The common presenting clinical features were abdominal mass or abdominal distension. Anatomical hepatic resections were carried out in 38 cases, and non anatomical resections in 34 cases. One patient died of a direct result of hepatic resection(1.4%), and complication rate was 16.4%.
Carcinoma, Hepatocellular ; Child* ; Focal Nodular Hyperplasia ; Hamartoma ; Hemangioendothelioma ; Hemangioma ; Hepatoblastoma ; Humans ; Liver ; Sarcoma

Focal nodular hyperplasia (FNH) is a rare benign hepatic tumor occurring predominantly in women of childbearing age. Generally oral contraceptive is not associated with FNH but might accentuate the vascular abnormalities which may cause the lesion to enlarge and, very rarely, to rupture. FNH is typically asymptomatic and seldom bleeds. Often it is incidentally observed during imaging procedures performed for some other reasons. The histologic feature of FNH is characterized by areas of localized growth of mature hepatocytes and septal fibrosis. Surgical resection is seldom required because of the benign nature of the lesion and its lack of significant complication. We experienced a case of focal nodular hyperplasia without liver cirrhosis confirmed by surgical resection and histologic examination. in a 47-year-old man.
Female ; Fibrosis ; Focal Nodular Hyperplasia* ; Hepatocytes ; Humans ; Liver Cirrhosis ; Liver* ; Middle Aged ; Rupture

During the past decades, a number of reports have described benign liver tumors in young women using oral contraceptives. The masses were usually found incidentally in physical examination or were identified as the source of a spontaneous intraperitoneal hemorrhage. Focal nodular hyperplasia(FNH) is the one of these benign tumor of the liver. We report a case of an incidentally discovered mass of FNH in a 46-year-old man which was incidentally discovered.
Contraceptives, Oral ; Female ; Focal Nodular Hyperplasia* ; Hemorrhage ; Humans ; Liver* ; Middle Aged ; Physical Examination