1.Potential Use of Bischofia javanica as an Active Ingredient of Functional Foods and Cosmeceutical Products Possessing Hyaluronidase, Collagenase, Tyrosinase and Urease Inhibitory Effects
Florin BARLA ; Asako HORINISHI ; Naoki HARADA ; Ryoichi YAMAJI ; Toshiki ENOMOTO ; Nobutaka SUZUKI ; Hisayuki MAENAKA ; Yoshihisa NAKANO ; Hiroshi INUI
Japanese Journal of Complementary and Alternative Medicine 2010;7(2):129-133
Bischofia javanica leaf extract exhibited inhibitory activities against hyaluronidase, collagenase, tyrosinase and urease, suggesting that it is useful as an active ingredient for functional foods and cosmeceutical products. In particular, its 50% inhibitory concentration for hyaluronidase was comparable to that of disodium cromoglycate, which is a well-known hyaluronidase inhibitor used as an anti-inflammation and anti-allergy agent. In addition, the extract also inhibited urease with the almost the same potential as acetohydroxamic acid, which is reported to suppress Helicobacter pylori-induced gastritis by inhibiting urease.
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