1.Complicated intra-abdominal infections: a prospective validation study of the WSES Sepsis Severity Score.
Saleh ABDEL-KADER ; Massimo SARTELLI ; Fikri M ABU-ZIDAN
Singapore medical journal 2019;60(6):317-321
INTRODUCTION:
The World Society of Emergency Surgery (WSES) recently developed and validated a sepsis severity score for complicated intra-abdominal infections (cIAIs). We aimed to prospectively study the validity of this score in our local setting and compare it with global findings.
METHODS:
In a prospective study of 100 consecutive adult patients with cIAIs treated at Al-Ain Hospital, United Arab Emirates, from October 2014 to January 2016, we studied patients' demographics, disease, risk factors, WSES Sepsis Severity Score, management, hospital stay and mortality. Our findings were compared with those from a recent global multicentre prospective study from 53 countries (n = 4,496).
RESULTS:
Compared with global data, our patients were more likely to be male (p < 0.0001) and younger (p < 0.0001), with more appendicitis and perforated peptic ulcers (p < 0.0001), significantly lower sepsis severity score (p < 0.0001) and more delays in surgical intervention (p = 0.001). Nevertheless, they had similar adequate source control (p = 0.54) and surgical reinterventions (p = 0.63). Overall, our patients had a significantly lower mortality rate (1.0% vs. 9.3% in global data; p = 0.001). A direct logistic regression model showed that the WSES Sepsis Severity Score significantly predicted mortality (p < 0.0001), but our hospital's setting was not predictive of mortality compared with other hospitals (p = 0.18).
CONCLUSION
Although our patient demographics and hospital's setting significantly differed from those of other international hospitals, the WSES Sepsis Severity Score was very accurate in predicting mortality among our patients, which supports its generalisability for all patient populations worldwide.
2.Management of computed tomography-detected pneumothorax in patients with blunt trauma: experience from a community-based hospital.
Ashraf F HEFNY ; Fathima T KUNHIVALAPPIL ; Nikolay MATEV ; Norman A AVILA ; Masoud O BASHIR ; Fikri M ABU-ZIDAN
Singapore medical journal 2018;59(3):150-154
INTRODUCTIONDiagnoses of pneumothorax, especially occult pneumothorax, have increased as the use of computed tomography (CT) for imaging trauma patients becomes near-routine. However, the need for chest tube insertion remains controversial. We aimed to study the management of pneumothorax detected on CT among patients with blunt trauma, including the decision for tube thoracostomy, in a community-based hospital.
METHODSChest CT scans of patients with blunt trauma treated at Al Rahba Hospital, Abu Dhabi, United Arab Emirates, from October 2010 to October 2014 were retrospectively studied. Variables studied included demography, mechanism of injury, endotracheal intubation, pneumothorax volume, chest tube insertion, Injury Severity Score, hospital length of stay and mortality.
RESULTSCT was performed in 703 patients with blunt trauma. Overall, pneumothorax was detected on CT for 74 (10.5%) patients. Among the 65 patients for whom pneumothorax was detected before chest tube insertion, 25 (38.5%) needed chest tube insertion, while 40 (61.5%) did not. Backward stepwise likelihood regression showed that independent factors that significantly predicted chest tube insertion were endotracheal intubation (p = 0.01), non-United Arab Emirates nationality (p = 0.01) and pneumothorax volume (p = 0.03). The receiver operating characteristic curve showed that the best pneumothorax volume that predicted chest tube insertion was 30 mL.
CONCLUSIONChest tube was inserted in less than half of the patients with blunt trauma for whom pneumothorax was detected on CT. Pneumothorax volume should be considered in decision-making regarding chest tube insertion. Conservative treatment may be sufficient for pneumothorax of volume < 30 mL.
Adolescent ; Adult ; Aged ; Chest Tubes ; Child ; Decision Making ; Female ; Humans ; Length of Stay ; Male ; Middle Aged ; Pneumothorax ; complications ; diagnostic imaging ; ROC Curve ; Retrospective Studies ; Severity of Illness Index ; Thoracic Injuries ; complications ; diagnostic imaging ; Thoracostomy ; Tomography, X-Ray Computed ; United Arab Emirates ; Wounds, Nonpenetrating ; complications ; diagnostic imaging ; Young Adult