1.A Case of Multiple Leiomyoblastoma of the Stomach.
Suck Jun KIM ; Chang Gi LEE ; Jin Seouk PARK ; Chang Keun WOO ; So Jung KWON ; Sang Moon LEE ; Choong Ki LEE ; Hyo Jong BAEK
Korean Journal of Gastrointestinal Endoscopy 1997;17(6):806-811
Gastric leiomyoblastoma is an uncommon intramural tumor, Its been regarded as a tumor of smooth muscle origin by its histological and electronmicroscopic characteristics. However, recent immunohistochemical staining techniques have shown that tumors diagnosed as leiomyoblastoma may have different tumor origins. We report a case of multiple leiomyoblastoma of the stomach thought to be of unknown derivation by Immunohistochemical study.
Leiomyoma, Epithelioid*
;
Muscle, Smooth
;
Stomach*
2.A Case of Leiomyoblastoma.
Ok Jae LEE ; Jee Hoon LEE ; Woo Song HA ; Kyung Hyuck KO
Korean Journal of Gastrointestinal Endoscopy 1996;16(6):989-993
Leiomyoblastoma is uncommon and has been known as a neoplasm of smooth muscle origin. However, with recent pragress in immunohistochemical staining techniques, many clinicopathological discrepancies have been pointed out about the origin of leiomyoblastoma. We present here a case of gastric leiomyoblastoma did not expressed desmin and neuron specific enolase, and was thought to be of unknown derivation.
Desmin
;
Leiomyoma, Epithelioid*
;
Muscle, Smooth
;
Phosphopyruvate Hydratase
3.A Case of Leiomyoblastoma.
Ok Jae LEE ; Jee Hoon LEE ; Woo Song HA ; Kyung Hyuck KO
Korean Journal of Gastrointestinal Endoscopy 1996;16(6):989-993
Leiomyoblastoma is uncommon and has been known as a neoplasm of smooth muscle origin. However, with recent pragress in immunohistochemical staining techniques, many clinicopathological discrepancies have been pointed out about the origin of leiomyoblastoma. We present here a case of gastric leiomyoblastoma did not expressed desmin and neuron specific enolase, and was thought to be of unknown derivation.
Desmin
;
Leiomyoma, Epithelioid*
;
Muscle, Smooth
;
Phosphopyruvate Hydratase
5.A Case of Gastric Leiomyoblastma.
Young Oh KWEON ; Eun Young KIM ; Jae Yong PARK ; Ho Gak KIM ; Kyu Sik KWAK ; Yong Hwan CHOI ; Joon Mo CHUNG
Korean Journal of Gastrointestinal Endoscopy 1988;8(1):45-48
A 48 year-old man was admitted with the chief complaint of epigastric pain for 10 days. With upper gastrointetinal series and gastrofiberscopy, there noted a round hemispherical submucosal tumar at lesser curvature side of stomach. Because of continuous epigastric pain and large submucosal mass with mucosal ulceration the patient undewent operation. After subtotal gastrectomy, we found the round well-demarcated tumor with mucosal ulceratian and hemarrhage, which located at muscular layer. Microscopically, dominent cells of tumor are round or polygonal epithelioid cells, which cytoplasm was lightly eosinophilic and was tightly coadenced about nucleus so that the bulk of the cell appeared clear. In the immunohistochemistry with desmin, the tumor cells are positive. Histological diagnosis was leiomyoblastoma of stomach. In 1960 Martin et al. described six cases of unusual round cell myogenic tumor of stomach. In 1962, Stout report a series of 69 similar cases and he proposed the term leiomyoblastoma'. Until recent, leiomyoblastoma are rare and largely misdiagnosed as leiomyoma or leiomyosarcoma. A careful histological study is recommended in case of smooth muscle cell tumor of stomach
Cytoplasm
;
Desmin
;
Diagnosis
;
Eosinophils
;
Epithelioid Cells
;
Gastrectomy
;
Humans
;
Immunohistochemistry
;
Leiomyoma
;
Leiomyoma, Epithelioid
;
Leiomyosarcoma
;
Middle Aged
;
Myocytes, Smooth Muscle
;
Stomach
;
Ulcer
6.A Case of Leiomyoblastoma of Stomach.
Sang Pal LEE ; Duk Key JANG ; Yong Jun HUR ; Young Ki CHUNG ; Dae Sik WON ; Dong Ryong SEO ; Doo Bok PAK
Korean Journal of Gastrointestinal Endoscopy 1988;8(2):141-144
In 1960 Martin and his associates described another type of tumor of the stomach derived from the smooth muscle, which they named myoid tumor in a study of six patients. In 1962 Stout applied the term "lelomyoblastoma" to this interesting entity in a report of a collected series of 69 patients. Tumor cells are round or polygonal epithelioid cells, which contain perinuclear vacuole or clear zone. A 58 year-old female was admitted to this hospital because of epigastric discomfort for three months. At Upper gastrointestinal series and gastrofiberscope, a round hemispherical submucosal tumor was noted at posterior wall near the lesser curvature of gastric antrum. After subtotal gastrectomy, the submucosal tumor was diagnosed as leiomyoblastoma. Because leiomyoblastoma are rare and easily misdiagnosed as leiomyoma or leiomyosarcoma, careful histologic study is recommended.
Epithelioid Cells
;
Female
;
Gastrectomy
;
Humans
;
Leiomyoma
;
Leiomyoma, Epithelioid*
;
Leiomyosarcoma
;
Middle Aged
;
Muscle, Smooth
;
Pyloric Antrum
;
Stomach*
;
Vacuoles
7.Intravascular leiomyomatosis with extrarenal rhabdoid cells: report of a case.
Hongjie SONG ; Yujuan JI ; Bingyu CHEN
Chinese Journal of Pathology 2014;43(2):128-130
Actins
;
metabolism
;
Calcium-Binding Proteins
;
metabolism
;
Calmodulin-Binding Proteins
;
metabolism
;
Desmin
;
metabolism
;
Diagnosis, Differential
;
Female
;
Humans
;
Hysterectomy
;
Leiomyoma, Epithelioid
;
metabolism
;
pathology
;
Leiomyomatosis
;
metabolism
;
pathology
;
surgery
;
Leiomyosarcoma
;
pathology
;
Microfilament Proteins
;
metabolism
;
Middle Aged
;
Receptors, Estrogen
;
metabolism
;
Receptors, Progesterone
;
metabolism
;
Rhabdoid Tumor
;
metabolism
;
pathology
;
surgery
;
Sarcoma, Endometrial Stromal
;
metabolism
;
pathology
;
Uterine Neoplasms
;
metabolism
;
pathology
;
surgery
;
Vascular Neoplasms
;
metabolism
;
pathology
;
surgery
;
Veins
;
pathology
;
Vimentin
;
metabolism
8.Uterine Leiomyomas with Perinodular Hydropic Degeneration: A Report of Two Cases.
Sung Nam KIM ; Jaejung JANG ; Kyu Rae KIM
Korean Journal of Pathology 2002;36(4):257-261
Hydropic degeneration is a frequent degenerative change in otherwise typical uterine leiomyomas. Very rarely, however, a significant amount of edema fluid accumulates around the fascicles of neoplastic smooth muscle bundles and forms the characteristic multinodular growth pattern that is called perinodular hydropic degeneration of leiomyoma (PHDL). The gross findings, showing a vague worm-like appearance and very rarely having an extrauterine extension, and the microscopic features, showing perinodular retraction artifacts forming pseudovascular spaces, make it difficult to differentiate the tumor from intravenous leiomyomatosis or myxoid leiomyosarcoma. We described two cases of leiomyomas showing perinodular hydropic degeneration (PHD), a condition that has rarely been described in English literature, and discussed the mechanism of forming "extrauterine extension" or cotyledonoid features. One of our cases showed the typical features of cotyledonoid dissecting leiomyoma, the other showed those of intramural dissecting leiomyoma. An awareness of the gross and microscopic findings of PHDL is important not to overdiagnose a benign smooth muscle neoplasm as a more aggressive type of tumor. It is thought that intramural dissecting leiomyoma, cotyledonoid dissecting leiomyoma, and PHDL are not distinct, but closely related subtypes showing different phases of evolutionary changes.
Artifacts
;
Edema
;
Leiomyoma*
;
Leiomyomatosis
;
Leiomyosarcoma
;
Muscle, Smooth
9.Post hysterectomy intravenous leiomyomatosis:multimodality imaging appearances
The Medical Journal of Malaysia 2015;70(3):205-207
Intravenous leiomyomatosis (IVL) is extremely rare with just
around 300 cases reported in literature. 1 With its unusual
growth pattern and clinically aggressive behavior, this
benign tumor can masquerade as a malignancy and present
a diagnostic challenge. Concurrent uterine fibroids or recent
hysterectomy for the same often provides a hint towards the
diagnosis. 2 The median interval between hysterectomy and
diagnosis of IVL is approximately 4 years. 3 We present a case
of IVL detected 10-years post total hysterectomy, bilateral
salpingo-oophorectomy (THBSO) and parametriectomy with
emphasis on multimodality imaging with multip
Leiomyomatosis
10.A Case of Malignant PEComa of the Uterus Associated with Intramural Leiomyoma and Endometrial Carcinoma.
Yoo Jin CHOI ; Jin Hwa HONG ; Aeree KIM ; Hankyeom KIM ; Hyeyoon CHANG
Journal of Pathology and Translational Medicine 2016;50(6):469-473
Perivascular epithelioid cell tumors (PEComas) refers to a family of mesenchymal neoplasms composed of angiomyolipomas, clear cell “sugar” tumors of the lung, and lymphangioleiomyomatoses. These tumors have a distinctive and common component of perivascular epithelioid cells that show an association with blood vessel walls and immunohistochemically display myomelanocytic differentiation. The unique neoplasms have been shown to have an expanded range through a variety of case reports, including visceral, intra-abdominal, soft tissue, and bone tumors. The retroperitoneum, abdominopelvic region, and uterus have been reported to be the most common sites. Most PEComas follow a benign course. However, reports of malignant PEComas are increasing. Many papers have described uterine PEComas, but to our knowledge, there have not yet been any reports of a malignant PEComa arising concomitant with another epithelial tumor and mesenchymal tumor. We report herein the case of a 67-year-old woman who experienced a malignant uterine PEComa infiltrating a preexisting intramural leiomyoma with synchronous well differentiated endometrial carcinoma and multiple liver and lung metastases.
Aged
;
Angiomyolipoma
;
Blood Vessels
;
Endometrial Neoplasms*
;
Epithelioid Cells
;
Female
;
Humans
;
Leiomyoma*
;
Liver
;
Lung
;
Lymphangioleiomyomatosis
;
Neoplasm Metastasis
;
Perivascular Epithelioid Cell Neoplasms*
;
Uterus*