To compare the hemodynamic effects of propofol, midazolam and etomidate during induction in sick children.Methods:Sixty sick children were randomly divided into three group s to receive intravenous propofol 2.5mg·kg-1(groupP),midazolam 0.2mg·kg-1(group M) or etomidate 0.3mg·kg-1(groupE), respectively. All hemodynamic data were recorded before administration, during intubation a nd 1,3,5,10 min after intubation. Results: The Bp and HR h ad no change in group Pand group Mduring whole procedure. In group E, the Bp had increased significantly at intubation to 1,3 min after intubation. Conclusion: propofol, midazolam and etomidate may be safely adminis trated for sick children during induction of anaesthesia.