AIM： To investigate the current situation and future trend of use of antineoplastics.METHODS： By using the methods of order of sum of money and order of frequency,the antineoplastics,annually used in Rujin Hospital's tumor ward,were analysed.RESULTS： 30 different kinds of antineoplastics for injection and 12 different kinds of tablets that used to assist the chemotherapy were often used.Some new chemotherapeutants were at the top of the order of sum of money and tablets were often used,too.CONCLUSION： It is important to speed up the development of Chinese domestic chemotherapeutants,cut down the expenses for chemotherapy,steadily improve the rationality and effectiveness of the medicine used.

Purpose:To study whether immune factors are involved in the occurrence of immune thrombocytopenia in some malignancy. Methods:Platelet associated antibodies and immune function were examined in 30 cases of malignancy with thrombocytopenia in our hospital. Results:Platelet associated antibodies(pAIgG,pAIgA,pAIgM)increased significantly in 11 of 30 patients with malignancy,especially those with metastatic adenocarcinoma and in the middle or advanced stage. Bleeding is common in these patients. After being treated with corticosteroid, immunosuppressive drugs or immunoglobulin,the platelet count of the patients increased and the bleeding syndrome improved. Conclusions:Thrombocytopenia in malignancy is partly due to the abnormal immune reaction of the patients.

The different levels and clinical significance of high sensitivity C reactive protein(hs-CRP) , tumor necrosis factor-a ( TNF-α) , erythrocyte sedimentation rate ( ESR) , and urinary monocyte chemoattractant protein-1 (uMCP-1) in 84 type 2 diabetic patients with different urine albumin excretion (UAE) were observed. The results indicated that the levels of hs-CRP,TNF-α,urinary MCP-1 ,and ESR in diabetic patients were significantly higher than those in control group,and the first three indexes increased with the levels of UAE. The results suggest that diabetic nephropathy seems to be correlated with inflammatory reactions.

Objective To summarize complications and nursing measures of patients with coronary angiography and stent implantation.Methods 62 patients with coronary angiography and stent implantation were retrospectively analyzed.Results There were 8 patients with bleed-ing,1 patients with chest pain,1 patient with heart dysfunction,2 patients with hypotension,2 patients with chest tightness,2 patients with secondary epilepsy,3 patients with digestive tract symptoms.After careful nursing,all the patients recovered.Conclusion Deep understanding of clinical material of patients before operation,preoperative education,close intraoperative monitor-ing of condition changes,close cooperation and observation and nursing of complications after the operation could improve the success rate of operation and rehabilitation of patients,so it is of great significance in clinic.

Objective To summarize complications and nursing measures of patients with coronary angiography and stent implantation.Methods 62 patients with coronary angiography and stent implantation were retrospectively analyzed.Results There were 8 patients with bleed-ing,1 patients with chest pain,1 patient with heart dysfunction,2 patients with hypotension,2 patients with chest tightness,2 patients with secondary epilepsy,3 patients with digestive tract symptoms.After careful nursing,all the patients recovered.Conclusion Deep understanding of clinical material of patients before operation,preoperative education,close intraoperative monitor-ing of condition changes,close cooperation and observation and nursing of complications after the operation could improve the success rate of operation and rehabilitation of patients,so it is of great significance in clinic.