1.Efficacy of butylphthalide on elderly patients with acute cerebral infarction and its effect on serum uric acid, c-reactive protein, and hemorheology
Fengzhu MENG ; Kai WEN ; Hua GAO ; Xuemei LIN ; Fang WANG
Drug Evaluation Research 2017;40(1):96-99
Objective To investigate the efficacy of butylphthalide on elderly patients with acute cerebral infarction and its effect on serum uric acid,c-reactive protein,and hemorheology.Methods Elderly patients (86 cases) with acute cerebral infarction in Xi'an No.1 Hospital from January 2015 to December 2015 were randomly divided into two groups.The control group was treated with conventional symptomatic treatment of acute cerebral infarction,observation group added with butylphthalide soft capsules.The NIHSS score and efficacy of the two groups,the serum uric acid,c-reactive protein,and the change of hemorheology before and after treatment were compared.Results The effective rate of observation group was 90.70%,significantly higher than that of control group 72.09% (P < 0.05);The NIHSS score,serum uric acid and c-reactive protein levels,blood viscosity and platelet aggregation rate of two groups after treatment were significantly lower (P < 0.05),the Barthel index were significantly increased (P < 0.05),and the change of observation group were more significant (P < 0.05).Conclusion Butylphthalide has high curative effect on elderly patients with acute cerebral infarction,can reduce the level of serum uric acid,c-reactive protein and the degree of nerve function defect,improve the hemorheology and life self-care activities ability,which can protect the brain.
2.Efficacy observation of Vitamin B2 combined with smecta in treatment of diaper rash
Fengzhu LIN ; Fang HUANG ; Xiaotang YU ; Yuqun WEN
China Modern Doctor 2014;(24):131-133
Objective To observe the efficacy of vitamin B2 combined with smecta in the treatment of infant diaper rash. Methods Fifty-nine infants were divided into the treatment group with 32 infants and the control group with 27 infants. The treatment group was given vitamin B2 combined with smecta treatment and the control group was given zinc oxide treatment. The efficacy was observed after 7 days of treatment. Results The remarkably effective rate of the treatment group was 87.5% and the total effective rate was 96.9%. The remarkably effective rate of the control group was 22.2% and the total effective rate was 66.7%. Statistical analysis showed that the two groups were significantly dif-ferent in the efficacy (P<0.01). Conclusion Vitamin B2 combined with smecta is a safe and reliable treatment scheme for infant diaper rash.