[Abstract ] Objective Explore the clinical pathological characteristics and diagnostic methods on ent mucous epidermoid carcinoma.Methods Collection of 20 cases with ent mucous epidermoid carcinoma in our hospital,using immunohistochemical method to detect patients with CK and EMA,CEA and CK8 ex-pression.Results Twenty patients were men,of which the high differentiation of 17 cases,3 cases of poorly differentiated.CK ,EMA and CEA in patients with tumor tissue and CK8 were positive expression. Conclusions Ent mucous epidermoid carcinoma is a kind of relatively rare ent tumor,its clinical patholog-ical features and tumor tissue in CK and EMA,CEA and CK8 expressed help to identify and diagnosis.

OBJECTIVE: To analyze the false-negative proportion and reasons of positioning test in benign paroxysmal positional vertigo (BPPV). METHOD: Sixty-eight cases were reviewed and analyzed during February to April 2009. All patients had typical clinical history of BPPV and diagnosed by positioning test,and all were treated with PRM successfully. If positioning test at the first time were negative, examinations repeated after either head shaking or return visits. RESULT: Thirteen patients (19.12%) appeared false-negative in positoning test, and 11 cases showed typical nystagmus after head shaking,while 2 cases were diagnosed by return visitis the next day. There were no statistically difference between false-negative group and positive group in age (P > 0.05), gender (P > 0.05), course of disease (P > 0.05) and types of semi-circular canal (P > 0.05). CONCLUSION Re-examinations after head shaking or return visits are useful for the diagnosis in the suspected BPPV patients who have negative positioning test.
Benign Paroxysmal Positional Vertigo ; diagnosis ; therapy ; False Negative Reactions ; Humans ; Patient Positioning

OBJECTIVE: To compare the vertigo controlling situation between the endolymphatic sac decompression(ELSD) and semicircular canal occlusion (SCO) in stage 4 Ménière disease. METHOD: Fourteen patients who underwent endolymphatic sac decompression and 9 patients who underwent semicircular canal occlusion from 2009 to 2013 were followed. All patients has complete preoperative examination and postoperative follow-up. RESULT: The vetigo control of the patients underwent endolymphatic sac decompression: completely control 35.7%; basic control 28.6%; partly control 14.3%; the vetigo control of the patients underwent semicircular canal occlusion: completely control 88.9%; basic control 11.1%. CONCLUSION ELSD and SCO are alternative methods for the patients of stage 4. SCO has a much highter complete vertigo control rate. For the patients without practical listening, SCO is a better choice.
Endolymphatic Sac ; surgery ; Humans ; Meniere Disease ; surgery ; Otologic Surgical Procedures ; methods ; Semicircular Canals ; surgery ; Vertigo ; surgery

OBJECTIVE: To study on the expression and significance of MMP-2 and MMP-9 in the nasus epithelial carcinoma and their signification. METHOD: Fifty cases of epithelial carcinoma tissue and 50 cases of normal nasus tissue were detected for MMP-2 and 9 by immunohistochemistry technique (SP), and analysed their relationships between expression of MMP-and some clinical symptoms. RESULT: The positive ratio of expression of MMP-2 in 50 cases of epithelial carcinoma was 52.0% (26/50), which was significantly higher than those in the normal nasus tissue 28.0% (14/50), P < 0.05. The positive ratio of expression of MMP-9 in 50 cases of epithelial carcinoma was 58.0% (29/50), which was significantly higher than those in the normal nasus tissue 10.0% (5/50), P < 0.05. CONCLUSION It was suggested that there was a close relationship between pathogenesis and development of nasus epithelial carcinoma and the expression of MMP-2, MMP-9 in the epithelial carcinoma tissues. The positive results of MMP-2, MMP-9 is partly valid for diagnosis of prognosis rate of MMP-2 and MMP-9 expression was high in nasus epithelial carcinoma tissues, MMP-2 and MMP-9 expression levels might be able to provide prognostic information.
Carcinoma, Squamous Cell ; diagnosis ; metabolism ; pathology ; Female ; Humans ; Lymphatic Metastasis ; Matrix Metalloproteinase 2 ; metabolism ; Matrix Metalloproteinase 9 ; metabolism ; Prognosis ; Uterine Neoplasms ; diagnosis ; metabolism ; pathology