1.Association between knee joint medial meniscus extrusion and posterior root tears:Magnetic resonance imaging analysis
Fei LI ; Jun ZHANG ; Fengzhe WANG ; Shinong PAN
Chinese Journal of Tissue Engineering Research 2013;(43):7648-7653
BACKGROUND:Meniscal root damage is an important reason for meniscus extrusion. In recent years, there are many reports on the relationship between meniscus root injury and meniscus extrusion at abroad, but it is rare at home. OBJECTIVE:To investigate the correlation between knee medial meniscus extrusion and the medial meniscus posterior root tears. METHODS:A retrospective analysis of the MRI and arthroscopic findings of 84 patients with knee medial meniscus extrusion signs was conducted. Medial meniscus extrusion≥ 3 mm or length of medial meniscus extrusion/maximum diameter of meniscus extrusion ≥10%was defined as serious extrusion. The chi-square test analysis was used to analyze the correlation between posterior root tears and the medial meniscus extrusion. RESULTS AND CONCLUSION:MRI measurement results of medial meniscus extrusion (length of medial meniscus extrusion ≥ 3 mm or length of medial meniscus extrusion/maximum diameter of meniscus extrusion≥ 10%) was significantly related with the arthroscopic findings of posterior root tears (P<0.05) with the odds ratio and 95%confidence intervals of 25.04 (3.07-204.44) and 6.96 (1.38-35.19) respectively. The medial meniscus serious extrusion is closely related to posterior root tears of the medial meniscus, which is a significant feature of the meniscus posterior root tears.
2. Research progresses in differentiation of benign and malignant vertebral marrow lesions with MR fat quantitative imaging
Chinese Journal of Medical Imaging Technology 2020;36(8):1251-1254
Accurate diagnosis of benign and malignant vertebral marrow lesions is crucial for individual treatment strategy and prognosis assessment. The changes of fat content play an important role in the pathological process of vertebral marrow lesions. The research progresses of common MR fat quantitative imaging techniques for differentiation of benign and malignant vertebral marrow lesions were reviewed in this article.
3. Progresses in imaging study of sarcopenia
Chinese Journal of Medical Imaging Technology 2019;35(1):148-151
Sarcopenia is an aging-related syndrome characterized with progressive and generalized loss of skeletal muscle mass and strength with complex and various causes, which seriously affects the quality of the elderly's life. Quantitative and qualitative assessment of muscle mass with imaging techniques is an important factor in diagnosis of sarcopenia, which may provide reference for early diagnosis, therapeutic intervention and prevention. The progresses in imaging study of sarcopenia were reviewed in this article.
4.Reiview of metabolic syndrome in TCM clinical and experimental studies
Shuquan LYU ; Shufang ZHANG ; Zhenqiang WANG ; Kaiming QIAO ; Xiuhai SU ; Lina XIE ; Fengzhe SU ; Qinghai WANG
International Journal of Traditional Chinese Medicine 2017;39(3):277-280
The paper summarized the literature in recent 5 years about the researches on the metabolic syndrome (MS) in traditional Chinese medicine. The paper discussed the etiology and pathogenesis, summarized the clinical research and experiment of traditional Chinese medicine for MS.
5.Impact of workplace mindfulness on thriving at work of nursing staffs
Lijuan GAO ; Shuang CANG ; Chao FAN ; Yu SHI ; Fengzhe XIE ; Jinghui WANG ; Xiumei MA
Chinese Journal of Practical Nursing 2017;33(9):701-703
Objective To explore the influence and it′s mechanism of workplace mindfulness on thriving at work of nursing staffs. Methods A cross-section survey was conducted to collect data with an online method, the multiple line hierarchical regression analysis method was performed to test the relations between variables. Results The mean workplace mindfulness score of nursewas 4.74±0.63, the mean thriving score was 3.07 ± 0.71. Workplace mindfulness had a significantly positive prediction on thriving at work (β=0.344, P<0.01) of nurses. Conclusions Workplace mindfulness could affect nurses′thriving at work, which is beneficial to improve the growth and vitality of nursing staffs, which in turn to enhance them to abundant and vigorous life.
6.Acute crush injuries of skeletal muscle of mice with ice-compression therapy: a dynamic study with diffusion tensor imaging
Fengzhe WANG ; Shinong PAN ; Qi AN ; Hong SHU ; Qi LI ; He SUN ; Guangxin ZHANG ; Qiyong GUO
Chinese Journal of Radiology 2010;44(12):1329-1334
Objective To evaluate the value of ice-compression therapy in mice skeletal muscle after acute crush injuries and correlate treatment effect with different compression time by MR DTI. Methods Forty Weistar mice were randomly divided into 4 groups by random number table method: control group (A), 5 min compression time group( B), 15 min compression time group(C) and 30 min compression time group(D). Diffusion tensor imaging examinations were performed before, immediately after, 24, 48 and 72 hours after injuries. ADC and FA values were calculated by fiber tracking tool. The morphological changes were confirmed by histopathology, and immunohistochemical methods were used for the assessment of Desmin expression with mean of A value. Statistical analysis by LSD-t test and Spearman rank correlation.Results (1) For every group before injuries, ADC valueswere (1.38±0.04) ×10-3,(1.38±0.08) ×10-3, ( 1.34 ± 0. 05 ) × 10 -3, ( 1.36 ± 0. 09 ) × 10 -3 mm2/s respectively, FA value were 0. 46 ± 0. 05,0. 45 ±0. 03,0. 45 ± 0. 05,0. 48 ± 0. 04 respectively. ADC values increased significantly and FA values reduced in each group immediately after injuries compared with pre-injury values. ADC values were ( 1.84 ±0. 10) × 10-3, ( 1.79 ±0. 09) × 10-3, ( 1.55 ±0. 07) × 10-3, ( 1.57 ±0. 04) × 10 -3mm2/s respectively,FA value were 0. 21 ±0. 04, 0. 26 ±0. 03, 0. 31 ±0. 02, 0. 30 ±0. 04 respectively. ADC values were still higher and FA values lower than pre-injury values at 24 hours after injury in A, B groups. ADC values were (1.54±0.13) ×10-3, (1.57±0.13) × 10-3mm2/s, FA value were 0.25 ±0.03, 0.26±0.02. (2)DTT showed fibers distorted and the number of fiber bundles reduced, some separation and displacement in each group immediately after injury. C, D groups improved more than A, B groups over time. (3) The disorder arrangement of skeletal muscle cells with edema and filaments separation were found in HE staining after injury, but the degree mitigated in C, D groups. Desmin staining became lighter with fuzzy edge immediately and 24 hours after injury, and changed more than 72 hours after injury. (4) The correlation coefficients of ADC, FA values and A value were respectively - 0. 789 and 0. 763 ( P < 0. 05 ). Conclusions DTI can non-invasively reflect the pathological changes after acute crush injuries of muscles of mice and ice compression therapy. It is a useful method to guide ice compression treatment after acute crush injuries.
7.Measurement of medical student learning adaptability and analysis of the influencing factors
Yujin XIE ; Yu SHI ; Jinghui WANG ; Fengzhe XIE ; Libin YANG ; Xing MA ; Mingsi WANG ; Ruonan ZHANG ; Tao SUN ; Depin CAO
Chinese Journal of Medical Education Research 2017;16(5):433-438
Objective To measure the present situation of medical students' learning adaptability and find the influencing factors in order to revise Learning Adaptability Scale for medical students.Methods A stratified sampling method was used to collect 1 180 medical students from Harbin Medical University.Using the internal consistency reliability test,the reliability of the revised student learning adaptability scale was verified.Five common factors were extracted by the exploratory factor analysis of the principal analysis method,and Logistic regression was used to analyze the influencing factors of medical student learning adaptability.Results The revised Student Learning Adaptability Scale (Cronbach's Alpha=0.914) consists of 27 measurement items.It includes five dimensions,namely self-directed learning,information utilization,environment choice,stresses response and goal orientation.The results showed that the adaptability of medical students was moderate (3.28 ± 0.52),and the influencing factors included job position (OR =1.496,95% CI=1.114-2.009),academic achievement (OR =1.638,95 % CI=1.386-1.936),satisfaction with learning (OR=2.160,95%CI=1.745-2.673),professional satisfaction (OR=1.369,95%CI=1.092-1.718),professional interest (OR =1.426,95% CI=1.186-1.715) and employment prospects (OR =1.526,95% CI=1.251-1.862).Conclusion The reliability and validity of the Student Learning Adaptability Scale is appropriate.Medical students' learning adaptability is influenced by many factors.
8.The development of a scale to measure the proactive socialization behavior and its impact on ;turnover intention of new nurses
Xu LIU ; Shuo WANG ; Guangming CHANG ; Shu′e ZHANG ; Fengzhe XIE ; Yu SHI ; Jinghui WANG ; Xinyue GUO ; Dexin MENG
Chinese Journal of Practical Nursing 2017;33(3):216-219
Objective To preliminarily develop a scale to measure the proactive socialization behavior of new nurses and test validity and reliability of the scale, to explore the impact of proactive socialization behavior on turnover intention. Methods Using a questionnaire survey method to investigate 696 new nurses who had worked within three years in nursing organization, structural equation model and hierarchical line regression methods were performed to analyze the data. Results Proactive socialization behavior scale included eight items under one dimension;the consistency coefficient of scale was 0.858;new scale had a good convergent and predictive validity;the proactive socialization behavior of new nurses was significantly negative related to turnover intention (β=-0.236,P<0.01). Conclusions The proactive socialization behavior scale has a good reliability, convergent and predictive validity. Meanwhile, new nurses with higher level of proactive socialization behavior have lower turnover intention. Because they can quickly fit the new environment, role definition and organizational culture, which in turn organization embeddedness is promoted.
9.Theoretical construction of type classification for graduate supervisors and its transformation mode
Mingsi WANG ; Tao SUN ; Yujin XIE ; Fengzhe XIE ; Jinghui WANG ; Zhuowa SHA ; Zhen WANG ; Depin CAO
Chinese Journal of Medical Education Research 2018;17(3):217-224
The theoretical framework classifies the ideal types of graduate supervisors,which is based on "the attention that the supervisor pays on academic research" and "the attention that the supervisor pays on clerical work".The author elaborates the characteristics of each type of supervisor and enumerates some possible causes for the different types of supervisors.According to the occupational characteristics of the graduate supervisors in China and taking into account the two influence factors as "personal ambition" and "relative deprivation",a theoretical model of supervisor type transformation model based on academic research and clerical work is presented and the causes of this transformation are also briefly analyzed,which provides the theoretical basis for the related research and management practice of graduate supervisors.
10.Traditional Chinese Medicine Monomers in Treatment of Diabetic Retinopathy by Regulating PI3K/Akt Signaling Pathway: A Review
Huiyu JIA ; Zhihai FENG ; Wenshuai FENG ; Hongru ZHOU ; Rui CHENG ; Fengzhe YAN ; Shuqian WANG
Chinese Journal of Experimental Traditional Medical Formulae 2023;29(12):265-273
Diabetes retinopathy (DR) is an important cause that threatens the visual health of adults. There are some treatment methods of western medicine with definite efficacy, such as anti-vascular endothelial growth factor and laser photocoagulation, but they have many adverse reactions such as intraocular infection and visual field damage. Traditional Chinese medicine (TCM) therapies are safe and effective, which can complement western medicine. Phosphatidylinositol3-kinase (PI3K)/protein kinase B (Akt) signaling pathway regulates a range of processes including glucose metabolism, cell proliferation, and cell transcription and apoptosis, which is closely related to the occurrence and development of DR. Numerous studies have shown that TCM monomers can participate in maintaining the integrity of blood-retinal barrier and inhibiting retinal neovascularization and neurodegeneration in many aspects such as inhibiting oxidative stress and alleviating inflammatory reaction by regulating the PI3K/Akt pathway, so as to delay the progress of DR. Therefore, this study reviewed PI3K/Akt pathway and its relationship with DR, as well as the TCM monomers in interfering with DR based on PI3K/Akt pathway to provide some ideas for the prevention and treatment of DR in integrated TCM and western medicine.