Objective The purpose of this study was to describe the effect of behavioral intervention of secondary prevention on stroke. Methods 204 patients with stroke were divided into the observation group and the control group with 102 patients in each group at random. The health records were set up and self-designed scale for assessment of risk factors of recurrence of stroke was used to assess the patients' general conditions. Individual intensified education and behavior intervention were adopted in the observation group. Routine treatment and health education were used in the control group. The collected data before intervention, the third and 6th month after intervention were evaluated. The medication compliance, limbs rehabilitation exercises, bad living style, coming to hospital at regular intervals and recurrence rate of stroke were compared between the two groups. Results The observation group was superior to the control group in the following aspects, the mastering rate of disease knowledge, changes in bad living style and therapy compliance (P<0.01). Conclusions Behavioral intervention of secondary prevention could effectively reduce the recurrence of stroke and improve the living quality of patients.

Objective To explore the change of of plasma TSP-1 level in patients with coronary atherosclerosis and its relationship with the degree of coronary artery stenosis and related plasma cytokines.Methods A total of 79 patients with chest pain were divided into low score group (n =27),medium score group (n =26),and high score group (n =26) according to Gensini score.Another 27 normal controls were included as control group.The levels of plasma TSP-1,hs-CRP,MMP-9 and TGF-β1 were detected by enzyme-linked immunoassay,and the relationship between TSP-1 and Gensini score,hs-CRP,MMP-9 and TGF-β1was analyzed.Results There were significant differences in level of plasma TSP-1 between four groups (P ＜ 0.05).The level of TSP-1 in plasma was correlated with hs-CRP (r =0.4979,P ＜ 0.001),MMP-9 (r =0.3940,P ＜ 0.001) and TGF-β1 (r =0.4889,P ＜ 0.001).The multiple stepwise linear regression analysis showed that there was a correlation between the degree of coronary artery stenosis and the plasma TSP-1 level.Conclusion Plasma TSP-1 level can be used as a biomarker for coronary stenosis.

Objective To explore the change of of plasma TSP-1 level in patients with coronary atherosclerosis and its relationship with the degree of coronary artery stenosis and related plasma cytokines.Methods A total of 79 patients with chest pain were divided into low score group (n =27),medium score group (n =26),and high score group (n =26) according to Gensini score.Another 27 normal controls were included as control group.The levels of plasma TSP-1,hs-CRP,MMP-9 and TGF-β1 were detected by enzyme-linked immunoassay,and the relationship between TSP-1 and Gensini score,hs-CRP,MMP-9 and TGF-β1was analyzed.Results There were significant differences in level of plasma TSP-1 between four groups (P ＜ 0.05).The level of TSP-1 in plasma was correlated with hs-CRP (r =0.4979,P ＜ 0.001),MMP-9 (r =0.3940,P ＜ 0.001) and TGF-β1 (r =0.4889,P ＜ 0.001).The multiple stepwise linear regression analysis showed that there was a correlation between the degree of coronary artery stenosis and the plasma TSP-1 level.Conclusion Plasma TSP-1 level can be used as a biomarker for coronary stenosis.