mRNA and protein expression of interleukin 1? converting enzyme (ICE) were determined with RF PCR and immunohisto chemistry in brain tissue after complete ischemia followed by reperfusion of the forebrain of gerbil.The effect of radix salviae miltorrhizae was also studied. It was found that increased expression of ICEmRNA was induced during the 4 days after ischemia and reperfusion. Meanwhile, the increases in ICE positive reactivity were observed in glial cells in the regions of CA1 and cortex 1～4 days after ischemia and reperfusion, but the ICE positive reaction was inhibited under the effect of radix salviae miltiorrhizae(P

Objective To investigate the factors affecting the depression of patients with orthopedic trauma surgery and nursing countermeasures .Methods A total of 210 patients were chosen in our hospital from January 2012 to January 2013.The Self-rating Depression Scale (SDS), Social Support Rating Scale (SSRS) and general information questionnaires were used in the survey .Results A total of 190 cases of patients finished the investigation.83 patients (43.68%) did not had depression, 58 patients (30.53%) had mild depression, 29 patients (15.26%) had moderate depression, 20 (10.53%) patients had severe depression .The reason for depression in patients with univariate and multivariate Logistic regression analysis showed that self -financed medical care , diagnosis and treatment of worry , fear poor prognosis , bad attitude and other aspects of health care were the main factors in patients with depression , but a high degree of social support in patients with depression was the protective factors .Conclusions The incidence of depression in patients with orthopedic surgery was high.But intensive care from the medical staff , support from their families and intimate care from friends can help patients get rid of depression after orthopedic surgery .