Objective To find out the endoscopic characteristics of peptic ulcer disease in minority area. Methods Analysis of 28 547 endoscopic cases in Yanbian area during 1990- 1998. Results In all endoscopic cases,4 348 cases(15.23% ) of peptic ulcer were found.Among them,48.22% (2 097cases) were of duodenal ulcer,44.18% (1 921 cases) of gastric ulcer, and the rest 7.59% (330 cases) of complex ulcer. Among these cases,male and female patients were 2 974(19.05% ) and 1374(10.62% ) respectively. The positive detective rates between male and female patients have significant difference(P0.01). Conclusion It suggested that the positive detective rate of peptic ulcer in Han nationality was higher than that in Korea nationality at Yanbian area; and, the male patient were more than the female ones.