An experimental model of cerebral concussion induced by blunt force stroke in 46 guinea pigs was established. 30 out of 46 animals were unconscious immediately after stroke followed by recovery Within few minutes without any seuqel in the posttraumatic period The animals were killed at 3,6,12,24,48 and 72 hours, 1,2,3,4 weeks after injury. Within 72 hours after injury, some of axons of both the afferent and the efferent nerve fibers of the corpus callosum and the brain stem were swelling like necklace or disrupted into segments macrophage infiltration, glosis, satellitosis, pyknosis of nuclioli of neuron, lysis of nissles bodies, vascular reaction as well as the retraction of the torn ends of axon as demonstrated by the silver stain were observed in animals killed 24 and 48 hours after injury. The reaction mentioned above became milder and milder 1～4 weeks after injury. Brain contusion were produced in other 16 experimental animals. In 7 animals of control group, no change was observed

OBJECTIVETo study and compare the difference on the therapeutical effectiveness between paper splint adduction fixation and plaster abduction fixation in Bennett fracture.

METHODSIn the study, seventy outpatient were selected from October 2005 to April 2007, and devided into two groups randomly involving experiment group (35 cases with paper splint adduction fixation) and control group (35 cases with plaster abduction fixation). After the fracture clinical healed and removed fixation, the patients had been followed up 6 months. At the 6th, 8th, 12th, 16th, 20th, 24th week after fracture, the fracture hand had been scored and compared according to Gabriele's score system.

RESULTSAt the 8th, 12th, 16th and 20th week, the excellent rate of experiment group was higher than control group, there was significant difference (P<0.05) At 6th week and 24th week there was no significant difference (P>0.05). At 8th, 12th, 16th, 20th and 24th week, the functional score of experiment group was higher than control group, there was significant difference (P<0.05); At 6th week there was no significant difference (P>0.05).

CONCLUSIONThe paper splint adduction fixation could promote recovery of the hand function in Bennett fracture. In addition, the paper splint adduction fixation is comfortable to recipient. It could be spreaded in clinic as a effective fixation method.

Adolescent ; Adult ; Casts, Surgical ; External Fixators ; Female ; Fracture Fixation ; Fracture Healing ; Fractures, Bone ; therapy ; Humans ; Male ; Metacarpal Bones ; injuries ; Middle Aged ; Splints ; Treatment Outcome