Objective To observe ganglioside and rehabilitation care to early rehabilitation of patients with severe traumatic brain injury.Methods 66 patients with brain injury were randomly divided into the control group and the rehabilitation group with 33 cases in each group.Both groups were given conventional medication and ganglioside treatment.The control group was given routine care.In addition to the usual care,the rehabilitation group received the implementation of systematic and standardized early rehabilitation nursing.Oxidative stress status,Barthel index score,and quality of life were compared between two groups.Results Oxidative stress parameters of the two groups showed no significant difference.After hospital treatment,Barthel index score and quality of life in the rehabilitation group were significantly higher than those of the control group.Conclusions Rehabilitation care can reduce disability rates of head injury,and improve the quality of life of patients.

Objective To explore the the influence ofFurong-Tongmai capsules on myocardial expression of LN and CollagenⅢ in diabetes mellitus (DM) rats.Methods A total of 60 rats were randomly divided into the control group, the model group, the low-, middle- high-dosageFurong-Tongmai capsules group (n=10). The low-, middle-high-dosageFurong-Tongmai group was given 1.4, 0.7, 2.8 g/(kg body weight) Furong-Tongmai capsules. The other two groups were given the same dose of purified water. After 8 weeks treatment, the myocardial was taken to make pathology slice with SP immunohistochemistry staining. The expression of LN and CollagenⅢ were detected.Results Compared with model group, the expression of LN (0.67% ± 0.04%,0.65% ± 0.09%vs. 1.08% ± 0.13%) and CollagenⅢ (0.67% ± 0.15%, 0.69% ± 0.13%vs. 1.17% ± 0.12%) in the middle-high-dosageFurong-Tongmai groups significantly decreased (P<0.05). However, there were no statistical differences between the low-, middle- high-dosageFurong-Tongmai groups and the model group (P>0.05).Conclusions TheFurong-Tongmai capsules could inhibit the expression of LN and CollagenⅢ in DM rats.

Objective: To explore the related risk factors of perioperative pulmonary infection in elderly patients with hip fracture. Methods: From June 2010 to June 2017, 576 patients with hip fracture (age≥70 years) admitted in Beijing Fengsheng Special Hospital of Medical Traumatology and Orthopaedics were selected retrospectively.According to whether perioperative pulmonary infection occurred, 576 patients were divided into two groups: pulmonary infection group (n=145), non-pulmonary infection group (n=431). The clinical features were compared between the two groups.SPSS20.0 software was used for data processing.χ² test was used for comparison between groups.Logistic regression model was established to screen out independent risk factors. Results: Single factor analysis showed that older age [(82.46±5.56)years vs.(79.22±6.51)years, t=-5.381, P=0.000)], anemia (65.51% vs.31.55%, t=50.696, P=0.000), hypoalbuminemia (55.86% vs.18.10%, χ²=75.557, P=0.000) and heart failure (44.14% vs.13.69%, t=65.242, P=0.000) were independent risk factors of perioperative hip fracture. Conclusion The occurrence of perioperative pulmonary infection in elderly patients with hip fracture is the outcome of combined action of multiple factors.Old age, hypoalbuminemia and heart failure are the independent risk factors for perioperative pulmonary infection.

OBJECTIVETo study the correlation between syndrome differ classification of knee osteoarthritis and X-ray image, so as to provide evidence for clinical diagnosis and treatment.

METHODSFrom Jun. 2007 to Dec. 2007, 78 patients (108 knees) with knee osteoarthritis were reviewed, including 65 females (89 knees) and 13 males (19 knees), ranging in age from 41 to 77 years. According to the standards for the differentiation of syndrome in the treatment of knee osteoarthritis defined in Principle of Clinical Research for New Traditional Herbs, the patients were divided into three types: Type I, insufficiency of the liver and kidney, with stagnation of tendons and muscles, 43 knees; Type II, insufficiency of the spleen and kidney, with dampness infusion into bone and joints, 26 knees; Type I, deficiency of the liver and kidney, with inter-obstruction of phlegm and stasis 39 knees. Normotopia and lateral plain film of knee joint of weigh loading and in erect position, and patellofemoral Skyline plain flim was taken. Joint space narrow, osteophyte generation, subchondral osteosclerosis and subchondral cystic degeneration were evaluated. All data were analyzed by K independent samples nonparametric test in order to find out the correlation between syndrome differ classification of knee osteoarthritis and X-ray image.

RESULTSIt was shown that after K independent samples nonparametric test about syndrome differ classification of knee osteoarthritis and X-ray image: there were significant differences among three types about lateral patella osteophyte, condyles of tibia osteophyte and Type II was the most serious, Type I was secondary, Type II was the lightest. Other index had no obvious difference among the three groups.

CONCLUSIONThere is certain correlation between syndrome differ classification of knee osteoarthritis and X-ray image. There are significant differences among three types about lateral patella osteophyte, condyles of tibia osteophyte, the Type II is the most serious,Type I is secondary, Type II is the lightest. Consequently, it can be deduced that worse osteophyte is one of accordances of Type II-insufficiency of the spleen and kidney, with dampness infusion into bone and joints. And, the Type II is more serious stage in radiologic manifestation.

Adult ; Aged ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged ; Osteoarthritis, Knee ; classification ; diagnosis ; diagnostic imaging ; Radiography

OBJECTIVETo study and compare the difference on the therapeutical effectiveness between paper splint adduction fixation and plaster abduction fixation in Bennett fracture.

METHODSIn the study, seventy outpatient were selected from October 2005 to April 2007, and devided into two groups randomly involving experiment group (35 cases with paper splint adduction fixation) and control group (35 cases with plaster abduction fixation). After the fracture clinical healed and removed fixation, the patients had been followed up 6 months. At the 6th, 8th, 12th, 16th, 20th, 24th week after fracture, the fracture hand had been scored and compared according to Gabriele's score system.

RESULTSAt the 8th, 12th, 16th and 20th week, the excellent rate of experiment group was higher than control group, there was significant difference (P<0.05) At 6th week and 24th week there was no significant difference (P>0.05). At 8th, 12th, 16th, 20th and 24th week, the functional score of experiment group was higher than control group, there was significant difference (P<0.05); At 6th week there was no significant difference (P>0.05).

CONCLUSIONThe paper splint adduction fixation could promote recovery of the hand function in Bennett fracture. In addition, the paper splint adduction fixation is comfortable to recipient. It could be spreaded in clinic as a effective fixation method.

Adolescent ; Adult ; Casts, Surgical ; External Fixators ; Female ; Fracture Fixation ; Fracture Healing ; Fractures, Bone ; therapy ; Humans ; Male ; Metacarpal Bones ; injuries ; Middle Aged ; Splints ; Treatment Outcome

To evaluate the effect of Tripterygium Glycosides Tablets extract in the treatment of rheumatoid arthritis( RA). Clinical trials of treating rheumatoid arthritis with Tripterygium Glycosides Tablets published by Meta-analysis were retrieved from EMbase,PubMed,Clinical Trials,Web of Science,Cochrane Library,CNKI,Wanfang,VIP,CBM and Chi CTR,and comprehensively analyzed. A total of 3 studies were enrolled,the modified Sharp score( m TSS),tender join joint erosions( JE) and joint space narrowing( JSN) of Tripterygium Glycosides Tablets group were significant superior to those of control group,including positive drugs methotrexate( MTX) and salazopyridine( SSZ)( P<0. 01). Tripterygium Glycosides Tablets had an effect in treating RA. Due to the small sample size,this study shall be verified with high-quality,large-sample-size double-blinded RCTs.
Antirheumatic Agents ; pharmacology ; Arthritis, Rheumatoid ; drug therapy ; Glycosides ; pharmacology ; Humans ; Tablets ; Tripterygium ; chemistry