1.Influence of neo-adjuvant chemotherapy on progrsssive gastric cancer operation withi multi-disciplinary team
Fengqiang ZHOU ; Yanmei QI ; Huiguang GUO ; Hong XU ; Shilu JIN
Chinese Journal of Primary Medicine and Pharmacy 2012;19(3):373-375
Objective To discuss the influence of the progress and result in gastic cancer operation through application of neo-adjuvant chemotherapy in multi-disciplinary team (MDT).Methods Clinical data of the patients treated in MDT model 45 cases and non-MDT model(78 cases) were respectively analyzed,and the index about pathologic change,histologic transform and operative result between the two groups were compared.Results In the index of pathologic change,the incidence of abdominal adherence and ascites and pyloric obstruction in MDT model group were obviously less than non-MDT model group( P <0.05 ).In the index of histologic transform,texture of mesentery in MDT model group was more fragile than non-MDT model group( P <0.05).In the index of operative results,the operative duration and intra-operative bleeding in MDT model group were less than non-MDT model group (P <0.05).Conclusion Neo-adjuvant chemotherapy has certain influence in gastric caneer operation,but the successful operations were performed by standard and correct procedures.Therefore,optimizing combined therapy in MDT model and constructing preoperative evaluation system with neo-adjuvant chemotherapy.
2.Quantitative evaluation of myocardium deformation in patients with hypertrophic cardiomyopathy by cardiovascular magnetic resonance feature tracking
Fengqiang JIN ; Anna MOU ; Weilin TIAN ; Hui CHEN ; Qingwei SONG ; Ailian LIU ; Zhiyong LI
Chinese Journal of Medical Imaging Technology 2017;33(5):703-707
Objective To explore the value of cardiovascular magnetic resonance feature tracking (CMR-FT) in quantita tive evaluation of myocardium deformation in patients with hypertrophic cardiomyopathy (HCM).Methods Sixteen HCM patients (HCM group) and 18 healthy volunteers (control group) were enrolled and measured with CMR-FT.The differences of left ventricular (LV) end diastolic volume (LVEDV),LV end systolic volume (LVESV),LV ejection fraction (LVEF),left ventricular mass (LVMASS) and LV global radial strain (RS),LV global circumferential strain (CS) were compared between the two groups.The correlations between segmental wall thickness and segmental RS and CS were studied.And the correlation among global RS,CS and LVEDV,LVESV,LVEF,LVMASS were analyzed.Results LVMASS in HCM group was higher than that in control group ([133.74±79.13]g vs [76.87±14.15]g,P=0.01).No sig nificant differences of LVEDV,LVESV,LVEF were found between HCM group and control group (all P>0.05).Global RS and CS were significantly lower in HCM group than those in control group (RS:[27.05 ± 13.35]% vs [40.62 ± 4.92] %,P<0.01;CS:[-8.68± 5.56] % vs [-20.73 ± 1.56] %,P<0.01).No significant correlations was observed between segmental wall thickness and segmental RS (r=-0.41,P<0.01),CS (r=0.28,P<0.01),respectively.In HCM group,no significant correlations was observed between global RS (r=-0.36,-0.41,0.22,-0.36),CS (r=0.34,0.10,0.22,0.42) and LVEDV,LVESV,LVEF,LVMASS,respectively (all P>0.05).Conclusion CMR-FT is conducive to quantitative evaluate myocardial deformation in HCM patients.