The management of in vitro diagnostic(IVD)reagents in hospitals often faces issues such as the lack of a unified coding system,unclear consumption patterns,and unknown cost-to-income ratios.It is necessary to employ information systems to achieve comprehensive,detailed,and traceable management of IVD reagents.An information management system for IVD reagents based on unique coding is introduced,which integrates admission,acceptance,and consumption processes through unique codes.The system calculates the income per experimental item based on the consumption of IVD reagents and the charge for each experimental item.The system enhances the efficiency of the IVD reagent supply chain management and promotes detailed oversight of IVD reagent usage.

Objective To investigate the correlation of serum 25-hydroxy-vitamin D (25-OH-D) with lipid profiles in middle-aged and elderly patients.Methods A total of 284 patients aged over 40 years and admitted in our hospital from May 2016 to May 2017 were selected and divided into four groups according to 25-OH-D levels as the group of normal level which was not less than 30 ng/ml,the group of slight deficiency which was between 20 and 29 ng/ml,the group of moderate deficiency which was between 10 and 19 ng/ml,and the group of severely deficiency which was under 10 ng/ml.Fasting blood draw were taken to detect liver and renal functions,lipids,calcium,phosphorus and 25-OH-D levels.The level of lipids between groups was compared by one-way ANOVA,and the association between lipid profiles and 25-OH-D levels was assessed by Pearson correlation and multiple linear regression.Results The levels of triglyceride (TG),low density lipoprotein cholesterin (LDL-C) and total cholesterol/high density lipoprotein cholesterol (TC/HDL-C) were significantly higher and the HDL-C levels were significantly lower in the groups of severely deficiency,moderate deficiency and slight deficiency than in the normal group (P=0.035,P=0.015,P=0.013).The levels of serum 25-OH-D were significantly higher in HDL-C ≥ 1.04 mmol/L group than in H DL-C＜ 1.04 mmol/L group (Female P =0.007,male P=0.034).The correlation analysis showed that serum 25-OH-D level was positively associated with HDL-C (female r =0.309,P=0.002,male r =0.241,P=0.002).The multiple linear regression analysis showed that 25-OH-D level was positively correlated with HDL-C,after adjusting age,BMI,liver and kidney function,serum calcium and serum phosphorus (femaleβ =0.259,P =0.047,maleβ =0.217,P =0.049).Conclusion The incidence of vitamin D deficiency is high in middle-aged and elderly patients,and the level of serum 25-OH-D is positively correlated with HDL-C.

Objective : To investigate the correlation between nocturnal sleep duration combined with snoring in the first trimester of pregnancyand small for gestational age(SGA) ，large for gestational age(LGA) ． Methods : Multi- variate Logistic regression model was used to analyze the association between nocturnal sleep duration ，snoring， their combined effects and SGA，LGA. Results : Compared to nocturnal sleep duration 7 to 9 h in the first trimester of pregnancy，sleep duration＜7 h was positively correlated with SGA in male newborn( OR = 4. 22，95% CI : 1. 69 - 10. 52) ; After stratified by snoring，the sleep duration of snoring women＜7 h was positively correlated with SGA ( OR = 5. 68，95% CI : 1. 02－31. 51) ，and the sleep duration of non-snoring women＜7 h was positively correlated with LGA ( OR = 2. 10，95% CI : 1. 16 －3. 81) ． Conclusion Sleep duration＜7 h in the first trimester of preg- nancy is a risk factor for SGA and LGA，and snoring may enhance the association between sleep duration＜7 h in the first trimester of pregnancy and SGA．Pregnant women should keep adequate nocturnal sleep duration to reduce the risk of abnormal neonatal weight.