Objective To explore the effects of exogenous methionine on arsenical distribution in liver,blood and brain of mice exposed to sodium arsenite through drinking water. Methods The female Kunming mice were randomly divided into control group, the alone arsenic exposure group , the low level methionine intervention group, the moderate level methionine intervention group and the high level methionine intervention group, eight mice in each group . The mice in the experimental groups were exposed to sodium arsenite through drinking water at 50 mg/L arsenic for four consecutive weeks. And at the fourth week the 5 groups were treated intraperitoneally with saline solution (control and As group),100 mg/kg b.w,200 mg/kg b.w or 400 mg/kg b.w methionine,respectively . Twenty-four hours after cessation of methionine administration,mice were anaesthetized and rapidly dissected. The samples of blood,liver and brain were removed immediately for arsenic species analysis. Levels of inorganic arsenic (iAs),monomethylarsonic acid (MMA) and dimethylarsenic acid (DMA) were determined by HG-AAS method. Then total arsenic speciation( TAs), primary methylation ratio( PMR)and secondary methylation ratio( SMR)in each tissue were calculated. Results Compared with the control group, the levels of iAs, MMA, DMA and TAs in liver, brain and blood, were significantly higher in all experimental groups ( P

Moral consciousness is closely related to ethical culture,and the level of moral consciousness and its cultivation among medical staff are crucial for developing the national healthcare industry.Starting from the development of moral consciousness theories at home and abroad,this paper clarified the concept of moral consciousness,and systematically expounded the concept of medical staff's moral consciousness based on this.The medical staff's moral consciousness was scientifically analyzed from five dimensions,including moral awareness,moral emotional consciousness,moral value consciousness,moral behavioral consciousness,and moral developmental consciousness.Combining the actual situation,the current state where the overall medical staff's moral consciousness is improving while there are cases of moral misconduct is analyzed.From the understanding of the value of labor,the shaping of family relationships,the construction of the social environment,the promotion of traditional culture,and the improvement of safeguard policies,five aspects are explored to seek paths for cultivating and enhancing the medical staff's moral consciousness,providing new ideas for the cultivation of medical staff's moral consciousness.