1.Study on the Antioxidation Activity of Different Processed Products of Polygonum Multiflorum Thunb and Its Crude
Jin GU ; Ping LIU ; Fengcai MA
China Pharmacy 2001;0(11):-
OBJECTIVE:To study the antioxidation activity of different processed products of polygonum multiflorum thunb and its crude.METHODS:The capabilities of different processed products of polygonum multiflorum thunb and its crude in eliminating free radical were studied and compared by chemical luminescent technique.RESULTS:The luminescent inhibi?tion ratio was used to represent the activity of superoxide dismutase(SOD),the result showed that the ratio of luminescent in?hibition of the crude sample of polygonum multiflorum thunb ranked the top,i.e.the crud sample had the highest antioxidation activity,then the black bean product,product that steamed in clear soup and that steamed in black bean alcohol solu?tion.CONCLUSION:If one can develop a preparation method in which only the purgative component of polygonum multiflo?rum thunb were destroyed while the effective components remained,the tonification function of which can be enhanced and the anti-aging effect of which can be brought into full play.
2.Correlation between blood pressure variability and different types of stroke
Shihua SUI ; Hua XIN ; Fengcai GU ; Lihua DONG ; Xiuli JIANG ; Jiaping ZHENG
Chinese Journal of Neuromedicine 2017;16(3):300-304
Objective To explore the relationship between blood pressure variability and different types of stroke.Methods One hundred and twenty-five ischemic stroke subjects,78 hemorrhagic stroke patients and 66 non-stroke individuals,collected in our hospital from January 1,2013 to December 31,2015,were enrolled according to the inclusion and exclusion criteria.All indicators of blood pressure variability were calculated from 24 h ambulatory blood pressure,including nighttime blood pressure fall (BPF),moming surge in blood pressure (MBPS),standard deviation (SD),weighted SD (wSD),and coefficient of variation (CV).Results As compared with non-stroke subjects,ischemic and hemorrhagic stroke individuals had significantly increased systolic MBPS (P<0.05),and the systolic MBPS of ischemic stroke group was significantly lower than those of hemorrhagic stroke group (P<0.05).CV,wSD and BPF of systolic blood pressure (SBP) in the ischemic and hemorrhagic groups were significantly higher than those in the non-stroke subjects (P<0.05);CV and SBPF of diastolic blood pressure in hemorrhagic group were significantly different as compared those in the non-stroke subjects (P<0.05).The factors which were significantly associated with ischemic stroke in Logistic regression,included high-density lipoprotein,nighttime SBP,wSD of SBP,CV of SBP,while smoking,nighttime SBP,wSD of SBP,MBPS,and CV of SBP were observed as important influence factors for hemorrhagic stoke patients.Conclusion Whether ischemic stroke,or hemorrhagic stroke are associated with short-term blood pressure variability.
3.Analysis of virulence genes and the chromosomal 16S rRNA gene polymorphism of Yersinia enterocolitic in Jiangsu Province,2015
Lu ZHOU ; Chen DONG ; Hui GUO ; Yinhua WU ; Yongjie ZHANG ; Jing AI ; Ling GU ; Changjun BAO ; Minghao ZHOU ; Fengcai ZHU ; Zhongming TAN
Chinese Journal of Infectious Diseases 2018;36(1):34-37
Objective To reveal the virulence genes and the polymorphisms of chromosomal 16S rRNA gene of Yersinia enterocolitic strains isolated from different districts in Jiangsu Province,2015. Methods Five virulence genes(ail,virF,yadA,ystA and ystB)of Yersinia enterocolitic strains isolated from different districts in Jiangsu Province were detected by using polymerase chain reaction(PCR),and phylogenetic analysis of chromosomal 16S rRNA gene was performed by amplification and sequencing. Results In this study,73 Yersinia enterocolitic strains were collected in Jiangsu Province in 2015.Among them,56(76.7%)strains carried virulence genes,and ail-virF-yadA -ystA -ystB+were the dominate types in diarrhea patients and other hosts.All strains can be clustering into 4 groups according to the phylogenetic analysis of chromosomal 16S rRNA gene.Conclusions The non-pathogenic Yersinia enterocolitic(ystB+)is the dominant strain in Jiangsu province,and the pathogenic strains are also found in this region.The result of phylogenetic analysis of chromosomal 16S rRNA gene and the profiles of virulence genes are highly consistent.