Objective To design and develop an intelligent material cabinet system in the department to execute informatized management of auto replenishment,quality safety and statistical query.Methods The intelligent material cabinet system had the functions of auto replenishment after inventory prewarning,recalling material record after login of an authorized user,and quality control of enterprise qualification and expiration prewarning.Mircosoft.Net technology framework,C/S architecture design and MS SQL Server database were involved in to develop the system,which was composed of a weighing cell,an electronic display screen,a material tray,an intelligent material cabinet and etc.The cabinet system had uniprocessor and network versions,and realized medical material fine management based on the hospital intranet.Results The cabinet system contributed to standardized operation,high-efficiency transport and quality safety.Conclusion The cabinet system behaves well in standardized,streamlined and informatized medical material management,and thus is worthy promoting practically.

Objective:To investigate the effects of strain force on t he expression of osteoclast differentiation factor(ODF) and osteoclasto-genesis i nhibitory factor(OCIF) in human periodontal ligament cells (HPDLCs). Met hods: HPDLCs were subjected to cyclic strain force for 0, 6, 12 and 24 h ours, mRNA expression of ODF and OCIF were determined by RT-PCR. Result s:After treatment of the cells for 0,6,12 and 24 hours the ODF/?-actio n values were 0.7280?0.0261,0.6831?0.0411,0.5801?0.2230 and 0.4572?0.0373( P0.05) respectively.Conclusion:Strain force may decrease the expression of ODF and increase the expression of OCIF.

Objective:To establish the cephalometric norms of soft tissue of adults in Xi'an area with normal occlusion.Methods:120 college students with normal occlusion(60 male and 60 female), aged from 18-22 years old in Xi'an city were selected.Lateral cephalometric film was taken by cephalometer for all the subjects at intercuspal occlusion.Then the films were traced on vitriolic paper, and the points were put into computer through digitizier. Statistic analysis were made and the data were compared with norms of adolescents already obtained.Results:Studied by Holdaway analysis,in the males FH-PgG' and Li-Pg' Ls of adults were bigger than those of adolescents, while Ss-Ls,Sn-H,Ls-Si and H-N'pg' were smaller(P0.05).Conclusion:The 3 sets of norms of soft tissue analysis obtained through this study may be applied as the norms of adults with normal occlusion.

AIM: To isolate three kinds of bufadienolides composition from Venenum bufonis in order to investigate their antitumor activity in vitro.METHODS: Alcohol extraction and isolation by Silica gel colume were employed in this study.Their antitumor activities in vitro were evaluated by MTT colorimetric method.RESULTS: With such methods,three kinds of bufadienolides,including Bufalin,cinobufagin,and resibufogenin with purity above 90% were prepared.The in-vitro results showed that three kinds of bufadienolides had prominent inhibition effect on human lung cancer A549 cells,human breast cancer MDA-MB-435 cells in the range of 0.001 ?g/mL ～ 100 ?g/mL.CONCLUSION: Isolation by Silica gel colume can be used to separate three kinds of bufadienolides from Venenum bufonis and its constituents has prominent anti-cancer effects.

Objective:To observe the histological character of distraction osteogenesis(DO) in the mandible of goat using an intraoral tooth-supported distraction device. Methods:8 goats (7-9 months of age) were divided into 4 groups with 2 goats per group. After a bilateral mandibular corticectomy between the second and third premolars, self-produced intraoral tooth-supported distraction devices were cemented. 5 days after operation,the distraction devices were begun to be activated 0.25 mm every 12 hours to advance the anterior segment 8 mm in 16 days. The animals of 32 days group were injected with tetracycline fluorescence labeing at 10 ml/kg once perweek from the beginning of DO.The animals were sacrificed on day 8,16,32 and 48 separately post activation, and tetracycline fluorescence labeling,HE staining and Mallory's 3-color staining were performed. Results:Tetracycline fluorescence labeling showed that there was green-yellow fluorescence labeling new bone within the distraction gap; HE and Mallory's trichrome staining showed that new bone gradually formed from bilateral sides, gradually blending and remodeling. The fiber bundles and newly formed trabeculas and various cells in early phrases showed to be orientation-directed along the axis of distraction force. Conclusion: New bone can be formed and regenerated along the axis of distraction force within the distraction gap.

[Summary] The basic data and serum targets of 3 349 residents were collected by multi stage stratified cluster random sampling and analyzed by correlation and regression analysis to access its association with cardiovascular risk factors. The result showed that morbidity of hyperuricemia was 18. 85% . The risk of hyperuricemia was raised in people with high triglycerides, high low-density lipoprotein-cholesterol ( LDL-C), low high-density lipoprotein-cholesterol(HDL-C), and low estimated glomerular filtration rate(eGFR). The people with hyperuricemia are usually accompanied with many cardiovascular risk factors.

Attenuation reflectance Fourier transformation infrared spectrometry(ATR FTIRs) combined with clustering analysis was used to identify genus Zanthoxlum .The dendrogram of clustering analysis showed that there were obvious difference between genus different species of Zanthoxlum . The results are consistent with that of morphologic study and analyzing.This method is rapid, simple, effective and can be used for the identification of crude drugs.

Objective: To study the effects of TNF, IL-1 and IL-6 on bone resorption in cultured calvaria of newborn mice. Methods: Calvaria of newborn mice was cultured and exposed to TNF, IL-1 or IL-6 at various dosages for 48 hours (treated grooups), or without the above agents(control). Calcium concentration in culture medium was determined by atomic absorption spectrum apparatus. The calcium concentration of the treated groups versus that of the control was used as the absorption index. Results: The absorption indexes in the medium of treated groups were 1.92～3. 14 or 1. 85 ～ 3. 34 when the bone was exposed to TNF or IL-6 at 10 ～ 320 ng/ml, those were 1.36 ～ 2.32 when the bone was exposed to IL-1 at 2～64 ng/ ml. Conclusion: TNF, IL-1 and IL-6 may stimulate bone resorption of calvaria in newborn mice.

Objective: To observe the proliferation of periodontal ligament fibroblasts(PDLFs) under mechanical stretching. Methods: PDLFs were stretched by 6 cycles/min(5 seconds stretching and 5 seconds relaxing) with 12% stretching force through self-produced cultured cell loading system. At experimental time point 24,48 and 96 hours, the cells were counted and flow cytometry was employed to observe the proliferation of PDLFs. Results: 48 h and 96 h after stretch treatment the cells in experimental groups were significantly more than those in control groups respectively (P

Objective To explore the relationship of serum uric acid level with estimated glomerular filtration rate (eGFR) of elderly patients with hypertention based on a retrospective cohort study.Method The subjects included 465 cases who had a readmission after 3 years of follow-up in an original cohort of 1648 patients with diagnosis of essential hypertension in Fujian Provincial Hospital from August 2007 to September 2009.Multiple regression analysis was performed to examine the effect of serum uric acid level on renal function.Results Four hundred and sixty-five subjects were followed up for an average of 3.9 years.Mean patient age was 68.3 ± 9.7 years.There was no significant difference in uric acid between the baseline and 3 years later (P ＞ 0.05).Multiple regression analysis showed that after adjustment for age,gender,diabetes,body mass index,blood pressure etc,each 100 μmol/L-higher uric acid at baseline was associated with 4.40 ml· min-1· (1.73m2)-1 decrease in eGFR[95％ confidence interval (CI):-6.25--2.55,P ＜ 0.01].According to the alteration of the serum uric acid,all patients were divided into the group with decreased uric acid and the group with increase uric acid.The eGFR was lower in patients with increased uric acid than that in patients with decreased uric acid 3 years later [(70.63±21.54) ml· min-1 · (1.73m2)-1 vs (79.62±21.16) ml· min-1· (1.73 m2)-1,P ＜ 0.01] and there was no significant difference at baseline between the two groups (P ＞ 0.05).Multiple logistic regression analysis showed that after adjusting for aging,gender,diabetes,alteration of blood pressure etc,baseline uric acid was associated with a higher risk for eGFR decreasing more than 10 ml· min-1· (1.73 m2)-1 3 years later [hazard ratio (HR)=2.11,95％CI:1.24-3.59,P ＜ 0.01]; increased uric acid 3 years later resulted in a higher risk for renal function deterioration (HR=2.60,95％ CI:1.67-4.07,P ＜ 0.01).Conclusions Elderly hypertensive patients with baseline hyperuricemia have a lower eGFR,resulting an increased risk of chronic kidney disease.While the patients with declined uric acid had a lesser imparied renal function.It suggests that the improvement of uric acid may help to slow down the deterioration of renal function in elderly hypertensive patients.