Adjuvants, Immunologic ; therapeutic use ; Animals ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Phytotherapy ; Systemic Inflammatory Response Syndrome ; complications ; drug therapy

Through learning philosophy,human beings can overcome the fear of death and gain the wisdom of life.With the rapid development of modem high-tech,some people advocate to pursue the immortality of individual life using science and technology.This is the most restless thoughts,originating from the false belief of dogmatic rationalism:with the development of science and technology,human beings are possible to fully grasp the mysteries of the nature (including human body).In fact,nature as well as human body is always hidden in infinite mystery.The pursuit of immortality is from the pursuit of meaning.Setting up morality,making contribution,and achieving glory by writing are the legitimate ways for human beings to pursuit immortality as cultural animals.One just can pursue immortality in the cultural sense,but cannot pursue the immortality of individual life.

Dental Restoration, Permanent ; Humans ; Prosthesis Coloring

Acute Disease ; Aged, 80 and over ; Fibrin Fibrinogen Degradation Products ; analysis ; Humans ; Male ; Pulmonary Embolism

Objective To introduce the development of an adjustable and bed- type table for pleural puncture and observe its clinical effect. Methods 100 patients who were to undergo pleural puncture were divided into the experimental group and the control group with 50 cases in each group.The experimen-tal group adopted the adjustable and bed-type table for pleural puncture, while the control group used the conventional method.The pulse,respiration and artery blood oxygen saturation degree were observed. The ef-feet of puncture was also compared. Results The pulse and respiration increased and the artery blood oxygen saturation degree decreased after puncture,which were significantly different between the two groups. One- time success rate of puncture,comfort degree and satisfaction degree of patients in the experimental group were better than those of the control group. Conclusions Adjustable and bed- type table for pleu-ral puncture can reduce the uncomfort of patients and increase the success rate of puncture and satisfaction degree of patients.

Objective To study the correlation between human leukocyte antigen (HLA)-DRB1 alleles and anti neutrophil cytoplasmatic antibodies (ANCA) in Han and Uygur ulcerative colitis (UC)patients in Xinjiang region.Methods The serum ANCA was determined by indirect immunofluorescence assay in 62 Uygur UC patients,58 Han UC patients,188 Uygur and 184 Han healthy control individuals.HLA-DRB1 typing was performed by polymerase chain reaction-sequence based typing (PCR-SBT).The allele frequency of HLA-DRB1 was compared in ANCA positive and negative Han and Uygur patients as well as healthy controls.Stratified analysis was performed according to UC clinical type,severity and involvement.SPSS 17.0 software was applied for x2 test.Once P＜0.05,the odds ratio (OR) and 95％ confidence intervals (95％CI) was calculated.Results The positive rate of ANCA in Uygur UC patients (53.2％,33/62) was significantly higher than that of Han patients (34.5％,20/58) and the difference was statistically significant (x2=4.269,P =0.045).In Uygur,the gene frequency of HLA-DRB1 * 13 in ANCA positive UC patients (0.202)was significantly higher than that of ANCA negative patients (0.017) (x2 =10.092,P=0.016,OR=16.000,95％CI:2.892 to 88.524) and healthy controls (0.075) (x2=9.351,P＝0.040,OR=3.407,95％CI:1.666 to 6.971).The gene frequency of HLA-DRB1 * 13 in ANCA positive pancolitis type UC patients (9/15) was significantly higher than that of ANCA negative pancolitis type UC patients (1/14) and the difference was statistically significant (x2=8.955,P =0.040,OR =19.500,95％CI:2.787 to 136.461).However,in Han patients,there were no significant differences of HLA-DRB1 alleles frequencies among ANCA positive patients,ANCA negative patients and healthy controls (all P＞0.05),and the results of stratified analysis were same.Conclusions In Uygur UC patients of Xinjiang region,HLA-DRB1 * 13 may correlated with ANCA and with ANCA of pancolitis type UC patients.There is no such correlation in Han patients of Xinjiang region.

Recently,there had been many researches about the effects of brain nat-riuretic peptide(BNP)and N-terminal pro-brain natriuretic peptide(NT-proBNP)on diagnosis and differential diagnosis of cadiovascular disease,risk classification,assessment of the treatment,prognosis and screening.Some results had been applied to clinical.This article reviews the progress of BNP and NT-proBNP on pe-rioperative monitoring for congenital heart defect.

Objective To investigate the clinical efficacy and safety of montelukast combined with budesonide in the treatment of children with asthma. Methods 70 cases of children with asthma were randomly divided into group A and group B, included 35 cases in each group. Group A was treated with single budesonide and Group B was given montelukast combined with budesonide. The clinical efficacy of two groups of asthma was compared, the body temperature returned to normal time, the time of wheezing disappeared, the normal time of the laboratory index, the normal time of the chest radiograph, the inflammatory factors and the lung function indexes and the side effects. Results The clinical curative effect of group B was higher than that of group A(P<0.05); Body temperature in group B returned to normal time, the time of wheezing disappeared, the normal time of laboratory index was shorter than that of group A(P<0.05); Inflammatory factors and lung function were similar. After intervention, the inflammatory factors and lung function of group B were better than those of group A(P<0.05). There were no obvious side effects in the two groups. Conclusion The clinical efficacy and safety of montelukast combined with budesonide in the treatment of children with asthma can improve the symptoms of children, cause the symptoms to recite in a short time, reduce the inflammatory factors, improve lung function, no obvious adverse reactions, safety effective.

Objective To explore the controlling level of fasting blood glucose(FBG) and glucosylated hemoglobin(GH) in order to stop occurrence of nephropathy in diabetic mellitus.Methods Data was collected by retrospective study,analyzed by non-conditional Logistic regression.Then the controlling levels of blood glucose and glucosylated hemoglobin were studied by regression equation.Results It was regarded that under 6.8 mmol/L of FBG and 5.9% of GH,diabetic nephropathy can be prevented;while under 6.0 mmol/L of FBG and 5.3% of GH,the onset of diabetic nephropathy was strictly controlled.Conclusion it is more important to control strictly on the threshold of fasting blood glucose and glucosylated hemoglobin for prevention of diabetic nephropathy.

Objective The aim of this paper is to develop a holistic mathematical model to quantify the correlation between skin thermal sensation and noxious stimuli,since skin thermal pain is one of the most common problems in everyday life and the understanding of the underlying physical mechanisms is still not clear.Methods The model is developed by considering the biothermomechanical behaviour of skin tissue and by incorporating the current understanding of biophysical and neurophysiological mechanisms of pain sensation.Results The proposed model consisted of three interconnected sub-models: peripheral modulation of noxious stimuli,which converts the energy from a noxious thermal stimulus into electrical energy via nerve impulses;transmission,which transports these neural signals from the site of transduction in the skin to the spinal cord and brain;and modulation and perception in the spinal cord and brain.The model predictions agree well with existing experimental data.Conclusion With this model,a direct relationship has been built between the level of thermal pain sensation and the character of noxious stimuli.