Based on the analysis of Medical Independent Colleges,this article is trying to discuss how to set up majors innovatively,reform curriculum and teaching plans effectively By doing this,it aims to set up a bettor education model of Medical Independent Colleges with characteristics of the running of such Medical Independent Colleges.Wishing it can serve as an talent training model for the colleges of the same kind

The G protein-coupled receptor, GPR40, is a specific receptor for free fatty acids. Singnaling pathways are activated in islet ?-cells by fatty acids as binding to GPR40. Fatty acids regulate insulin secretion and cause ?-cell hyperplasia through GPR40. GPR40 also mediates responses to antidiabetic drugs like thiazolidinediones. GPR40 agonists and/or antagonists show potential effect in the development of new anti-diabetic drugs.

BACKGROUND:Induced pluripotent stem cell (iPSC) technique is a newborn technology reprogramming human somatic cells into pluripotent stem cells, which can be used in disease modeling, drug screening and cell therapy. OBJECTIVE: To analyze the feasibility and advances of iPSC application in Alzheimer's disease, and conclude the insufficient and future of this technology. METHODS:CNKI and PubMed were searched for relevant articles concerning Alzheimer's disease and iPSCs, and the retrieval results were screened by relativity and repeatability. Finally, 30 articles were included in result analysis. RESULTS AND CONCLUSION: This review concludes the superiority of iPSC technology in the treatment of neurodegenerative diseases and in vivo harvest of nerve cells. The use of inducible pluripotent stem cells differentiated from patient's own cells is more practicable, but there are still many problems to solve at this stage, such as high-efficient and stable directional differentiation, safety of induced pluripotent stem cells, the most appropriate donor cells, and ethical disputes.

Objective To analyze surgical diagnosis and treatment effect of 25 cases with gastric stump carcinoma.Methods The clinical manifestations and therapies of 25 cases with gastric stump carcinoma in our hospital from 1992 to 2003 were analyzed retrospectively.We sum up the surgical methods and postoperative survival rate.Results The postoperative survival rates of 1,3 and 5 years in 25 cases with gastric stump carcinoma were 60.2%,34.2% and 18.6% respectively,and were 81.4%,48.2% and 36.7% respectively in cases treated with radical resection.Conclusion No specific symptoms were identified,endoscopy examination periodically is the key point to detect gastric stump carcinoma.Radical resection is the most effective surgical style for surgical treatment of gastric stump carcinoma.

It has been indicated that the oncogene and anti-oncogene are closely related to the development and progression of cancer.With the development of molecular biology,detection of oncogene and anti-oncogene has become an important approach for clinical warning and diagnosing of cancer.Since the establishment of the molecular model of colon cancer by Fearon and Vogelstein in 1990,the genetics of colorectal cancer has gained major advances in early diagnosis.Early detection of related gene mutations is helpful for the early warning of colorectal cancer,especially for palients with hereditary cancer(the detection rate is fairly high).This review summarizes the progression of study on biomarkers of colorectal cancer.

Adenoma, Pleomorphic ; surgery ; Adult ; Female ; Humans ; Male ; Middle Aged ; Nasopharyngeal Neoplasms ; surgery

Objective:To investigate the effects of strain force on t he expression of osteoclast differentiation factor(ODF) and osteoclasto-genesis i nhibitory factor(OCIF) in human periodontal ligament cells (HPDLCs). Met hods: HPDLCs were subjected to cyclic strain force for 0, 6, 12 and 24 h ours, mRNA expression of ODF and OCIF were determined by RT-PCR. Result s:After treatment of the cells for 0,6,12 and 24 hours the ODF/?-actio n values were 0.7280?0.0261,0.6831?0.0411,0.5801?0.2230 and 0.4572?0.0373( P0.05) respectively.Conclusion:Strain force may decrease the expression of ODF and increase the expression of OCIF.

Objective To compare and analysis clinicopathological characteristics,and to investigate progno-sis factors of gastric cancer in young patients.Methods Clinicopathological data of 103 gastric cancer in young patients (YGC,18-44 years) who underwent surgery,endoscopic and pathology diagnosis in the affiliated Jincheng Coal General Hospital of Shanxi Medical University from January 2010 to December 2014 were analyzed retrospective-ly.A total of 315 gastric cancer in older patients ( OGC,≥60 years) during the same period patients were selected and compared to the young gastric cancer patients.Results The male to female ratios was 1 1.5 and the percentage of female patients was predominant in the 103 YGC patients,and there was statistically significant different (χ2 =32.03,P<0.01).The first clinical symptoms were upper abdominal pain and hemorrhagic anemia in most of the YGC group.Gastric antruma was most common in the occurrence site of the tumor of the YGC group.The incidence of the BorrmannⅢtype andⅣtype in YGC patients was statistically higher than that of the OGC group.With regard to his-tological type,the most frequency type in the YGC group was diffuse adenocarcinoma (83%),which was statistically significant different.As compared with the OGC patients,poorly differentiated adenocarcinoma and ring cell carcinoma were predominant pathological type in YGC (χ2 =41.51,P<0.01).Nothing can be compared with T3 stage and T4 stage of the depth of invasion,and clinical stage wereⅢstage andⅣstage in most of the YGC group (χ2 =48.78, P<0.01).Patients with a family history of cancer in YGC were higher than OGC,which was statistically different (χ2 =17.39,P<0.05).There were no statistical significant difference in tumor size,Hp infection rate,level of albu-min,level of serum CEA,vascular cancer embolus and incisal edge between the two groups.On univariate and multiva-riate analysis showed that the depth of invasion,degree of differentiation,lymph node metastasis,clinical stage and sur-gical methods were the independent risk factors associated with the prognosis of YGC.Conclusion The YGC patients are usually female,obviously hereditary tendency,and tumor most locate at gastric antruma.The first clinical symptoms are lacking in specific,but upper abdominal pain and hemorrhagic anemia in most of the YGC patients.Ⅲstage andⅣstage was most common of clinical stage.The YGC patients are usually poorly differentiation,highly ma-lignant,early metastasis and poorer prognosis.

In order to better accommodate heterogeneous quality of service (QoS) in wireless networks, an algorithm called QeS-aware power and admission controls (QAPAC) is proposed. The system is modeled as u non- cooperative game where the users adjust their transmit powers to maximize the utility, thus restraining the interferences. By using adaptive utility functions and tunable pricing parameters according to QoS levels, this algorithm can well meet different QoS reqniremcnts and improve system capacity compared with those that ignore the QoS differ- ences.

Objective: To evaluate the application value and potential faults of Dual-source CT in carotid arterial angiography.Methods: We retrospectively analyzed the images of 477 patients with symptomatic carotid atherosclerosis detected by dual-source CT angiography(CTA) from February 2007 to January 2008,and evaluated the quality of the images,which were classified into 3 quality grades: excellent(with clear display of the lesion and no noticeable motion artifacts,good(with a few motion artifacts but still diagnostically applicable),and poor(with heavy motion artifacts,unclear display and no diagnostic value).Results: Of the 477 images,420(88.1%) were of excellent quality,44(9.2%) of good quality and 13(2.7%) of poor quality.Among the total number of cases,134(28.1%) were shown to be normal and 34(7.1%) abnormal in anatomic structure.Atheromatous plaques were detected in 295 cases(61.8%),carotid artery stenting in 11(2.3%),internal carotid artery occlusion in 1,common carotid artery occlusion in 1,and cervical tumor in 3.Conclusion: Dual-source CT,faster,effective and minimally invasive,is particularly valuable in the diagnosis of carotid arterial lesion and stenosis.