2.Fiber post and its key point of application.
Chinese Journal of Stomatology 2011;46(7):442-445
6.The significances of the endoscopic diagnosis and histological assessment for chronic atrophic gastritis
Chinese Journal of Postgraduates of Medicine 2009;32(z2):52-53
Objective To explore the significances of the endoscopic diagnosis for chronic atrophic and histological assessment gastritis (CAG). Method Five hundred patients with CAG were determined by gastroscopy and the samples of gastric mucosa were examined by the pathology. Results Among 500 cases of CAG by gastroscopy, 429 cases were similar with the pathologic results and the coincidence rate of diagnosis with endoscopy and pathology was 85.8%(429/500), 370 cases had a change of atrophic gastritis in cirumjacent mucosa. Conclusion The coincidence rate of diagnosis under endoscopy and pathology is quite good in CAG.
7.The clinical meaning of 1h-plasma glucose cutoff value during OGTT in the screening of diabetes and IGR
Chinese Journal of Diabetes 2010;18(3):204-206
Objective To determine 1 hour plasma glucose cutoff value during OGTT to screen diabetes and IGR and its relationship with islet β cell function and insulin sensitivity. Methods 4731 subjects were recruited to perform an OGTT.The cutoff value of 1h-plasma glucose during OGTT was analyzed by receiver operating characteristic curve (ROC curve).And according to the two cutoff values,we classified all the subjects to three groups,and compared HOMA-IR,HOMA-β,insulinogenic index and shape index among groups,then analyzed its correlation with each parameter. Results According to ROC results, to diagnose type 2 diabetes mellitus,the optimal cutoff value of 1h plasma glucose during OGTT was 12.935mmol/L,with sensitivity of 81.52%,specificity of 86.94%. To diagnose impaired glucose regulation(IGR),the optimal cutoff value of 1h plasma glucose was 9.815mmol/L,with sensitivity of 74.96% and specificity of 77.86%. We classified all the subjects to three groups, and among the three groups the insulinogenic index, shape index, HOMA-IR, HOMA-β showed statistically significant difference (all P<0.01). There was a negative correlation of OGTT-1hPG with insulinogenic index and HOMA-β(all P<0.01) and a positive correlation of OGTT-1h PG with shape index and HOMA-IR (all P<0.01). Conclusions To diagnose type 2 diabetes mellitus,the optimal cutoff value of 1h plasma glucose during OGTT is 12.935mmol/L.To diagnose impaired glucose regulation(IGR),the optimal cutoff value of 1h plasma glucose is 9.815mmol/L.And 1h PG can reflect the islet β-cell function and insulin resistance.
8.Metastasis-related genes in human colorectal cancer:a literature review
International Journal of Surgery 2011;38(2):117-120
Colorectal cancer is one of the most commonly seen malignant neoplasms in digestive tract.Most patients with colorectal cancer died of metastasis.The details of the metastasis-associated mechanisms are not elucidated completely.Recently,many genes that are involved in this course were detected.In this paper,the latest advances in those metastasis-associated genes and coding genes including C-myc,Ras,Her-2 ,p53,deleted in colorectal cancer gene (DDC),phosphatase and tensin homologue (PTEN),nm23 and other code genes,such as CD44,matrix metalloproteinases (MMPs) and mucins will be reviewed.